{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:33:48Z","timestamp":1777491228299,"version":"3.51.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2021,1,11]],"date-time":"2021-01-11T00:00:00Z","timestamp":1610323200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2021,6]]},"abstract":"\n Background<\/jats:title>\n The objective of this study was to assess whether migraine-related outcomes changed during intelligent lockdown when compared with the prior period.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n This was a cohort study evaluating the first month of intelligent lockdown in the Netherlands (12 March to 8 April 2020) compared with one baseline month (13 February to 11 March 2020). We identified 870 migraine patients treated at the Leiden Headache Center with headache e-diaries during the period of interest. Adherence to the e-diary had to be \u226580%, yielding 592 enrolled patients.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Intelligent lockdown led to a decrease in monthly migraine days (\u22120.48; 95% CI: \u22120.78 to \u22120.18, p\u2009=\u20090.002) and acute medication days (\u22120.48; 95% CI: \u22120.76 to \u22120.20, p\u2009<\u20090.001), and an increase in general well-being (0.11; 95% CI: 0.06 to 0.17, p\u2009<\u20090.001). No differences in non-migrainous headache days and pain coping were observed. Consistent results were found in a subset that was followed for 4 months.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Our findings imply that intelligent lockdown measures can improve migraine disability despite of the potential negative effects of COVID-19 and lockdown. We hypothesise that this effect is a combined result of working from home, scaling down demanding social lives, and freedom to choose how to organise one\u2019s time.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/0333102420981739","type":"journal-article","created":{"date-parts":[[2021,1,14]],"date-time":"2021-01-14T19:55:19Z","timestamp":1610654119000},"page":"865-870","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":56,"title":["Effect of lockdown during COVID-19 on migraine: A longitudinal cohort study"],"prefix":"10.1177","volume":"41","author":[{"given":"Iris E","family":"Verhagen","sequence":"first","affiliation":[{"name":"Department of Neurology, Leiden University Medical Center, Leiden, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daphne S","family":"van Casteren","sequence":"additional","affiliation":[{"name":"Department of Neurology, Leiden University Medical Center, Leiden, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone","family":"de Vries Lentsch","sequence":"additional","affiliation":[{"name":"Department of Neurology, Leiden University Medical Center, Leiden, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gisela M","family":"Terwindt","sequence":"additional","affiliation":[{"name":"Department of Neurology, Leiden University Medical Center, Leiden, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,1,11]]},"reference":[{"key":"bibr1-0333102420981739","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2020.1452"},{"key":"bibr2-0333102420981739","doi-asserted-by":"publisher","DOI":"10.1111\/head.13810"},{"key":"bibr3-0333102420981739","doi-asserted-by":"publisher","DOI":"10.1177\/0333102411418846"},{"key":"bibr4-0333102420981739","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2006.01155.x"},{"key":"bibr5-0333102420981739","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00034.2015"},{"key":"bibr6-0333102420981739","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(14)70220-0"},{"key":"bibr7-0333102420981739","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.53.3.537"},{"key":"bibr8-0333102420981739","doi-asserted-by":"publisher","DOI":"10.1177\/0333102417738202"},{"key":"bibr9-0333102420981739","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000003376"}],"container-title":["Cephalalgia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0333102420981739","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0333102420981739","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0333102420981739","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:49:01Z","timestamp":1777387741000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0333102420981739"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,11]]},"references-count":9,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1177\/0333102420981739"],"URL":"https:\/\/doi.org\/10.1177\/0333102420981739","relation":{},"ISSN":["0333-1024","1468-2982"],"issn-type":[{"value":"0333-1024","type":"print"},{"value":"1468-2982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,11]]}}}