{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:35:39Z","timestamp":1777491339608,"version":"3.51.4"},"reference-count":34,"publisher":"SAGE Publications","issue":"4-5","license":[{"start":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T00:00:00Z","timestamp":1632700800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:p>New daily persistent headache is described as an enigmatic condition with daily headache from onset. It has posed challenges diagnostically and therapeutically.<\/jats:p>\n                  <jats:p>Methods: We conducted a study of patients referred to headache services based in Central and North-East London, United Kingdom, meeting the International Classificaiton of Headache Disorders \u2013 3 criteria for New daily persistent headache. Information on demographics, phenotype and treatment responses were collected. The syndrome of the daily headache was also classified according any other ICHD-3-defined syndrome.<\/jats:p>\n                  <jats:p>Results: Of 162 patients, females comprised 68.5% with median age of onset 35 years. The daily headache experienced was chronic migraine in 89.7% and tension-type headache in 8.8%. Thunderclap-onset New daily persistent headache occurred in 14.8%. More than one headache syndrome was experienced in 15.4%, including cough, hypnic, sexual and stabbing headache. All aura types were experienced, most commonly brainstem aura in 39%. Prior headache was reported 53.7%. A persisting sub-form was present in 51.2%, relapsing remitting in 12.3% and 14.0% reported improvement; 19.8% were lost to follow-up. Only 11.1% reported an antecedent trigger. The most common premorbid disorders were psychiatric in 35.7%. A fifth improved on preventative medication, most commonly amitriptyline, propranolol and topiramate.<\/jats:p>\n                  <jats:p>Conclusion: Our cohort of New daily persistent headache is consistent with a mode of onset of migraine and tension-type headache which occurs in predisposed individuals.<\/jats:p>","DOI":"10.1177\/03331024211044440","type":"journal-article","created":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T22:13:11Z","timestamp":1632780791000},"page":"385-395","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":20,"title":["Time to retire \u2018New daily persistent headache\u2019: Mode of onset of chronic migraine and tension-type headache"],"prefix":"10.1177","volume":"42","author":[{"given":"Rhannon","family":"Lobo","sequence":"first","affiliation":[{"name":"National Hospital for Neurology and Neurosurgery, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Shanxi Provincial People\u2019s Hospital, Taiyuan, 030012, Shanxi Province, China"},{"name":"Section for Nutrition Research, Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sean","family":"Lobo","sequence":"additional","affiliation":[{"name":"Faculty of Life Science and Medicine, King's College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9495-9006","authenticated-orcid":false,"given":"Anish","family":"Bahra","sequence":"additional","affiliation":[{"name":"National Hospital for Neurology and Neurosurgery, London, UK"},{"name":"Department of Neurology, Barts Health NHS Trust, Whipps Cross Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,9,27]]},"reference":[{"key":"bibr1-03331024211044440","first-page":"318","volume":"26","author":"Vanast WJ.","year":"1986","journal-title":"Headache"},{"key":"bibr2-03331024211044440","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2004.02.006"},{"key":"bibr3-03331024211044440","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2008.01647.x"},{"key":"bibr4-03331024211044440","doi-asserted-by":"publisher","DOI":"10.1177\/0333102417738202"},{"key":"bibr5-03331024211044440","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000137039.08724.18"},{"key":"bibr6-03331024211044440","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2004.00771.x"},{"key":"bibr7-03331024211044440","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-004-0310-8"},{"key":"bibr8-03331024211044440","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.1996.3606349.x"},{"key":"bibr9-03331024211044440","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181dad5de"},{"key":"bibr10-03331024211044440","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-019-1022-z"},{"key":"bibr11-03331024211044440","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2009.01842.x"},{"key":"bibr12-03331024211044440","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2007.01288.x"},{"key":"bibr13-03331024211044440","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2011.01872.x"},{"key":"bibr14-03331024211044440","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000335946.53860.1d"},{"key":"bibr15-03331024211044440","doi-asserted-by":"publisher","DOI":"10.1097\/01.wco.0000227040.16071.a9"},{"key":"bibr16-03331024211044440","doi-asserted-by":"publisher","DOI":"10.1177\/0333102418769948"},{"key":"bibr17-03331024211044440","doi-asserted-by":"publisher","DOI":"10.1177\/0333102418806869"},{"key":"bibr18-03331024211044440","doi-asserted-by":"publisher","DOI":"10.1186\/1129-2377-14-100"},{"key":"bibr19-03331024211044440","doi-asserted-by":"publisher","DOI":"10.1002\/ejp.1000"},{"key":"bibr20-03331024211044440","doi-asserted-by":"publisher","DOI":"10.1177\/0333102420920644"},{"key":"bibr21-03331024211044440","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2011.02046.x"},{"key":"bibr22-03331024211044440","unstructured":"British Association for the Study of Headache Guideline Group. 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