{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T02:54:29Z","timestamp":1787799269621,"version":"build-2784847793"},"reference-count":35,"publisher":"SAGE Publications","issue":"4-5","license":[{"start":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T00:00:00Z","timestamp":1632700800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Hormonal and menstrual factors are known to influence migraines in women. However, studies in the postmenopausal period are relatively insufficient for clinical translation. This study investigated the influence of endogenous and exogenous hormonal factors on migraines in spontaneous menopausal women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We obtained and analyzed the data related to hormonal factors from the Korean Health Examination database. A migraine diagnosis was identified using the Korean National Health Insurance Service database between 2009 and 2018. We observed migraine occurrence in spontaneous postmenopausal women. Study populations were divided into two groups depending on new diagnosis of migraine during the follow up periods. We investigated the association between endogenous and exogenous hormonal factors and migraine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>1,114,742 spontaneous postmenopausal women were enrolled. Migraine risk tended to increase in the shorter lifetime number of years of menstruation group compared to the group with lifetime number of years of menstruation \u226540 years. All of the hormone replacement therapy (HRT) groups showed higher risk compared with the non-HRT group. Migraine risk tends to increase with greater postmenopausal years compared to the postmenopausal &lt;5 years group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our study suggests that female hormonal factors, including endogenous and exogenous estrogen exposure, may be associated with migraine occurrence in spontaneous menopausal women.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03331024211044441","type":"journal-article","created":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T22:13:11Z","timestamp":1632780791000},"page":"376-384","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["The influence of endogenous and exogenous hormonal factors on migraine in spontaneous postmenopausal women: A nationwide population-based study in South Korea"],"prefix":"10.1177","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2077-309X","authenticated-orcid":false,"given":"Seonghoon","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Neurology, Uijeongbu St. Mary\u2019s Hospital, the Catholic University of Korea, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si Baek","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Neurology, Uijeongbu St. Mary\u2019s Hospital, the Catholic University of Korea, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun Jeong","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Neurology, Uijeongbu St. Mary\u2019s Hospital, the Catholic University of Korea, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongbang","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurology, Uijeongbu St. Mary\u2019s Hospital, the Catholic University of Korea, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyungdo","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Statistics and Actuarial Science, College of Natural Sciences, Soongsil University, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong Wook","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Neurology, Uijeongbu St. Mary\u2019s Hospital, the Catholic University of Korea, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,9,27]]},"reference":[{"key":"bibr1-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.23903"},{"key":"bibr2-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1607393"},{"key":"bibr3-03331024211044441","unstructured":"Research on the menopause.\n                      World Health Organ Tech Rep Ser\n                      1981; 670: 1\u2013120."},{"key":"bibr4-03331024211044441","first-page":"773","volume":"7","author":"Ripa P","year":"2015","journal-title":"Int J Womens Health"},{"key":"bibr5-03331024211044441","doi-asserted-by":"publisher","DOI":"10.3109\/13697130009167613"},{"key":"bibr6-03331024211044441","doi-asserted-by":"publisher","DOI":"10.3109\/13697139909038065"},{"key":"bibr7-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1159\/000336838"},{"key":"bibr8-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2003.03092.x"},{"key":"bibr9-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-015-2155-8"},{"key":"bibr10-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2000.00027.x"},{"key":"bibr11-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5594.735"},{"key":"bibr12-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2016.164"},{"key":"bibr13-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2006.01557.x"},{"key":"bibr14-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1089\/154099903322643956"},{"key":"bibr15-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1080\/14656566.2017.1414182"},{"key":"bibr16-03331024211044441","first-page":"799","volume":"46","author":"Cheol Seong S","year":"2017","journal-title":"Int J Epidemiol"},{"key":"bibr17-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182535d20"},{"key":"bibr18-03331024211044441","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2020.35.e406"},{"key":"bibr19-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmi018"},{"key":"bibr20-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13381"},{"key":"bibr21-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2011.371"},{"key":"bibr22-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-007-9574-z"},{"key":"bibr23-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-018-3333-2"},{"key":"bibr24-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2006.00309.x"},{"key":"bibr25-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0762-05.2005"},{"key":"bibr26-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2006.00370.x"},{"key":"bibr27-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2435457100"},{"key":"bibr28-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1016\/j.spen.2016.01.005"},{"key":"bibr29-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000000091"},{"key":"bibr30-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1016\/0378-5122(93)90121-W"},{"key":"bibr31-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2007.02.006"},{"key":"bibr32-03331024211044441","first-page":"1495","volume":"81","author":"Santoro N","year":"1996","journal-title":"J Clin Endocrinol Metabol"},{"key":"bibr33-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1111\/head.12763"},{"key":"bibr34-03331024211044441","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2003.03005.x"},{"key":"bibr35-03331024211044441","doi-asserted-by":"publisher","DOI":"10.2147\/NDT.S285863"}],"container-title":["Cephalalgia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03331024211044441","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03331024211044441","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03331024211044441","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:49:16Z","timestamp":1777387756000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03331024211044441"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,27]]},"references-count":35,"journal-issue":{"issue":"4-5","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["10.1177\/03331024211044441"],"URL":"https:\/\/doi.org\/10.1177\/03331024211044441","relation":{},"ISSN":["0333-1024","1468-2982"],"issn-type":[{"value":"0333-1024","type":"print"},{"value":"1468-2982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,27]]}}}