{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T21:28:16Z","timestamp":1793741296637,"version":"4.6.1"},"reference-count":38,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100004336","name":"Novartis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004336","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007819","name":"Allergan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007819","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To estimate the prevalence, burden and current treatment of disabling primary headaches in a large sample of the Greek population aged 18\u201370 years old.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This is an observational descriptive study, with cross-sectional design performed by quantitative computer-assisted telephone interviews, using a validated 37-item questionnaire for headaches. The prevalence, burden, and current treatment of primary headaches (ICHD-3) were recorded along with participants\u2019 treatment preferences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Out of 10,008 interviewed participants, 1197 (12.0%) reported headaches affecting performance. The annual prevalence of migraine was 8.1% (95% confidence interval, 7.6\u20138.7, corresponding to 0.6 million Greeks), of chronic migraine 1.0% (95% confidence interval, 0.8\u20131.2, corresponding to 0.1 million), and of tension-type headache 3.8% (95% confidence interval, 3.4\u20134.2, corresponding to 0.3 million). The participants with headaches reported 0.5 headache-induced lost workdays per month (corresponding to 5.8 million lost workdays annually) and reductions in performance on 2.8 workdays per month (corresponding to 30.9 million workdays annually). In all, 43.4% of headache participants felt bad\/ashamed because of headaches and 21.9% sought professional treatment, most often from a private neurologist. 83.8% of headache participants had never taken pharmacological prophylaxis, and only 5.5% were currently under preventative treatment. For both prophylactic and acute treatment, headache participants prefer oral medication to injection or stimulation devices.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>More than 10% of the Greek adult population up to 70 years old experience disabling headaches, causing a dramatic work loss. More than 80% of these have never taken pharmacological prophylaxis. Thus, enriching the quality of life of people with headaches relies crucially on expanding awareness about headaches and their treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0333102421989630","type":"journal-article","created":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T23:34:45Z","timestamp":1612222485000},"page":"810-820","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["A population-based survey for disabling headaches in Greece: Prevalence, burden and treatment preferences"],"prefix":"10.1177","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2587-6255","authenticated-orcid":false,"given":"Theodoros S","family":"Constantinidis","sequence":"first","affiliation":[{"name":"Hellenic Headache Society, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chryssa","family":"Arvaniti","sequence":"additional","affiliation":[{"name":"Second Neurology Department, Attikon Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaos","family":"Fakas","sequence":"additional","affiliation":[{"name":"Neurology Department, 401 Army General Hospital of Athens, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jobst","family":"Rudolf","sequence":"additional","affiliation":[{"name":"Department of Neurology, Papageorgiou General Hospital, Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evangelos","family":"Kouremenos","sequence":"additional","affiliation":[{"name":"251 Air Forces General Hospital of Athens, Neurology Department, Leof. Pan. Kannelopoulou, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ermioni","family":"Giannouli","sequence":"additional","affiliation":[{"name":"Department of Neurology, Athens Medical Center, 5\u20137 Distomou, Marousi, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimos D","family":"Mitsikostas","sequence":"additional","affiliation":[{"name":"First Neurology Department, Aeginition Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,2,1]]},"reference":[{"key":"bibr1-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.1996.3603168.x"},{"key":"bibr2-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.1996.3609561.x"},{"key":"bibr3-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.1994.hed3409539.x"},{"key":"bibr4-0333102421989630","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1468-2982.1988.0801001.x","volume":"8","year":"1988","journal-title":"Cephalalgia"},{"key":"bibr5-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.1999.3910728.x"},{"key":"bibr6-0333102421989630","first-page":"1","volume":"24","author":"Headache Classification Committee of the International Headache Society.","year":"2004","journal-title":"Cephalalgia"},{"key":"bibr7-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1177\/0333102417738202"},{"key":"bibr8-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000000438"},{"key":"bibr9-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-015-0522-1"},{"key":"bibr10-0333102421989630","unstructured":"Hellenic Statistical Authority. 2011 population and housing census, http:\/\/www.statistics.gr\/en\/2011-census-pop-hous (2011, accessed 31 July 2018)."},{"key":"bibr11-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1177\/0333102413485658"},{"key":"bibr12-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1007\/s10194-010-0217-0"},{"key":"bibr13-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.51.1.21"},{"key":"bibr14-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2001.01147.x"},{"key":"bibr15-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1177\/0333102412438977"},{"key":"bibr16-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2006.00297.x"},{"key":"bibr17-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.53.3.537"},{"key":"bibr18-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1007\/s10194-011-0414-5"},{"key":"bibr19-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1159\/000008143"},{"key":"bibr20-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30322-3"},{"key":"bibr21-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.59.2.232"},{"key":"bibr22-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2005.00977.x"},{"key":"bibr23-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2004.00680.x"},{"key":"bibr24-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1177\/0333102419829909"},{"key":"bibr25-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2016.93"},{"key":"bibr26-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/837613"},{"key":"bibr27-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2006.01210.x"},{"key":"bibr28-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1159\/000116244"},{"key":"bibr29-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2007.01380.x"},{"key":"bibr30-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2008.01836.x"},{"key":"bibr31-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000233786.72356.3e"},{"key":"bibr32-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000150901.47293.BC"},{"key":"bibr33-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-2982.2003.00585.x"},{"key":"bibr34-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-016-2572-3"},{"key":"bibr35-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2011.03612.x"},{"key":"bibr36-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30322-3"},{"issue":"10","key":"bibr37-0333102421989630","volume":"19","author":"Katsarava Z","year":"2018","journal-title":"J Headache Pain"},{"key":"bibr38-0333102421989630","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-017-0813-3"}],"container-title":["Cephalalgia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0333102421989630","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0333102421989630","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0333102421989630","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:49:24Z","timestamp":1777387764000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0333102421989630"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,1]]},"references-count":38,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1177\/0333102421989630"],"URL":"https:\/\/doi.org\/10.1177\/0333102421989630","relation":{},"ISSN":["0333-1024","1468-2982"],"issn-type":[{"value":"0333-1024","type":"print"},{"value":"1468-2982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,1]]}}}