{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T18:55:12Z","timestamp":1782845712016,"version":"3.54.5"},"reference-count":18,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Only limited data are available regarding the treatment status and response to cluster headache in an Asian population. Therefore, this study aimed to provide a real-world treatment pattern of cluster headache and the response rate of each treatment in an Asian population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients with cluster headache were recruited between September 2016 and January 2019 from 16 hospitals in Korea. At the baseline visit, we surveyed the patients about their previous experience of cluster headache treatment, and acute and\/or preventive treatments were prescribed at the physician\u2019s discretion. Treatment response was prospectively evaluated using a structured case-report form at 2\u2009\u00b1\u20092 weeks after baseline visit and reassessed after three months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 295 recruited patients, 262 experiencing active bouts were included. Only one-third of patients reported a previous experience of evidence-based treatment. At the baseline visit, oral triptans (73.4%), verapamil (68.3%), and systemic steroids (55.6%) were the three most common treatments prescribed by the investigators. Most treatments were given as combination. For acute treatment, oral triptans and oxygen were effective in 90.1% and 86.8% of the patients, respectively; for preventive treatment, evidence-based treatments, i.e. monotherapy or different combinations of verapamil, lithium, systemic steroids, and suboccipital steroid injection, helped 75.0% to 91.8% of patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our data provide the first prospective analysis of treatment responses in an Asian population with cluster headache. The patients responded well to treatment despite the limited availability of treatment options, and this might be attributed at least in part by combination of medications. Most patients were previously undertreated, suggesting a need to raise awareness of cluster headache among primary physicians.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03331024231159627","type":"journal-article","created":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T04:11:48Z","timestamp":1677643908000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Treatment pattern and response for cluster headache in Korea: A prospective multicenter observation study"],"prefix":"10.1177","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1364-1969","authenticated-orcid":false,"given":"Mi Ji","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Neurology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong Wook","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Neurology, Uijeongbu St. Mary\u2019s Hospital, Catholic University of Korea College of Medicine, Uijeongbu, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6221-1346","authenticated-orcid":false,"given":"Min Kyung","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Neurology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heui-Soo","family":"Moon","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8726-4812","authenticated-orcid":false,"given":"Pil-Wook","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Myun","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Neurology, Inje University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong-Hee","family":"Sohn","sequence":"additional","affiliation":[{"name":"Department of Neurology, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung-Kun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurology, Eulji University School of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4014-9400","authenticated-orcid":false,"given":"Byung-Su","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurology, Bundang Jesaeng General Hospital, Daejin Medical Center, Seongnam, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0994-8503","authenticated-orcid":false,"given":"Soo-Kyoung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurology and Institute of Health Science, Gyeongsang National University College of Medicine, Jinju, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae-Jin","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Neurology, Seoul Hospital, Ewha Womans University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun-Ju","family":"Choi","sequence":"additional","affiliation":[{"name":"Dr. Choi\u2019s Neurology Clinic, Jeonju, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwang-Yeol","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Neurology, Chung-Ang University Hospital, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyungmi","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Neurology, Korea University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Young","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Neurology, Seoul Medical Center, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwang-Soo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Neurology, Seoul St. Mary\u2019s Hospital, Catholic University of Korea College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dae Woong","family":"Bae","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Catholic University of Korea, St Vincent's Hospital, Suwon, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4053-3763","authenticated-orcid":false,"given":"Soo-Jin","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Neurology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,3,1]]},"reference":[{"key":"bibr1-03331024231159627","doi-asserted-by":"publisher","DOI":"10.1111\/head.12866"},{"key":"bibr2-03331024231159627","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2006.01566.x"},{"key":"bibr3-03331024231159627","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-59366-9"},{"key":"bibr4-03331024231159627","doi-asserted-by":"publisher","DOI":"10.1177\/0333102419845660"},{"key":"bibr5-03331024231159627","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-018-0911-x"},{"key":"bibr6-03331024231159627","doi-asserted-by":"publisher","DOI":"10.1177\/0333102412469738"},{"key":"bibr7-03331024231159627","doi-asserted-by":"publisher","DOI":"10.1177\/0333102420923646"},{"key":"bibr8-03331024231159627","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2003.00721.x"},{"key":"bibr9-03331024231159627","first-page":"486","volume":"56","author":"Kernick 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