{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:15:20Z","timestamp":1777490120352,"version":"3.51.4"},"reference-count":41,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Data from some population-based studies have indicated an increased risk of atrial fibrillation (AF) among patients with migraine, particularly among individuals with migraine with aura. The present study aimed to assess the association between primary headache disorders and AF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In a population-based 9-year follow-up design, we evaluated the questionnaire-based headache diagnosis, migraine and tension-type headache (TTH) included, collected in the Tr\u00f8ndelag Health Study (HUNT3) conducted in 2006\u20132008, and the subsequent risk of AF in the period until December 2015. The population at risk consisted of 39,340 individuals \u226520 years without AF at HUNT3 baseline who answered headache questionnaire during HUNT3. The prospective association was evaluated by multivariable Cox proportional hazard models with 95% confidence intervals (CIs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among the 39,340 participants, 1524 (3.8%) developed AF during the 9-year follow up, whereof 91% of these were \u226555 years. In the multivariable analyses, adjusting for known confounders, we did not find any association between migraine or TTH and risk of AF. The adjusted hazard ratios (HRs) were respectively 0.84 (95% CI = 0.64\u20131.11) for migraine, 1.16 (95% CI = 0.86\u20131.27) for TTH and 1.04 (95% CI = 0.86\u20131.27) for unclassified headache. However, in sensitivity analyses of individuals aged \u226555 years, a lower risk of AF was found for migraine (HR = 0.53; 95% CI = 0.39\u20130.73).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this large population-based study, no increased risk of AF was found among individuals with migraine or TTH at baseline. Indeed, among individuals aged \u226555 years, migraine was associated with a lower risk for AF.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03331024241254517","type":"journal-article","created":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T05:04:09Z","timestamp":1716959049000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Migraine and risk of atrial fibrillation: A 9-year follow-up based on the Tr\u00f8ndelag Health Study"],"prefix":"10.1177","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4464-4951","authenticated-orcid":false,"given":"Samita","family":"Giri","sequence":"first","affiliation":[{"name":"Department of Neuromedicine and Movement Science, NTNU \u2013 Norwegian University of Science and Technology, Trondheim, Norway"},{"name":"NorHEAD \u2013 Norwegian Centre for Headache Research, NTNU, Trondheim, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erling","family":"Tronvik","sequence":"additional","affiliation":[{"name":"Department of Neuromedicine and Movement Science, NTNU \u2013 Norwegian University of Science and Technology, Trondheim, Norway"},{"name":"NorHEAD \u2013 Norwegian Centre for Headache Research, NTNU, Trondheim, Norway"},{"name":"Department of Neurology and Clinical Neurophysiology, St Olavs University Hospital, Trondheim, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e5vard","family":"Dalen","sequence":"additional","affiliation":[{"name":"Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway"},{"name":"Clinic of Cardiology, St Olavs University Hospital, Trondheim, Norway"},{"name":"Department of Medicine, Levanger Hospital, Nord-Tr\u00f8ndelag Hospital Trust, Levanger, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanne","family":"Ellekj\u00e6r","sequence":"additional","affiliation":[{"name":"Department of Neuromedicine and Movement Science, NTNU \u2013 Norwegian University of Science and Technology, Trondheim, Norway"},{"name":"Stroke Unit, Department of Internal Medicine, St Olavs University Hospital, Trondheim, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan P","family":"Loennechen","sequence":"additional","affiliation":[{"name":"Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway"},{"name":"Clinic of Cardiology, St Olavs University Hospital, Trondheim, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Olsen","sequence":"additional","affiliation":[{"name":"NorHEAD \u2013 Norwegian Centre for Headache Research, NTNU, Trondheim, Norway"},{"name":"Department of Psychology, Norwegian University of Science and Technology, Trondheim, Norway"},{"name":"Clinic of Rehabilitation, St Olavs University Hospital, Trondheim, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Knut","family":"Hagen","sequence":"additional","affiliation":[{"name":"Department of Neuromedicine and Movement Science, NTNU \u2013 Norwegian University of Science and Technology, Trondheim, Norway"},{"name":"NorHEAD \u2013 Norwegian Centre for Headache Research, NTNU, Trondheim, Norway"},{"name":"Clinical Research Unit, St Olavs University Hospital, Trondheim, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,5,29]]},"reference":[{"key":"bibr1-03331024241254517","doi-asserted-by":"publisher","DOI":"10.1111\/ene.12701"},{"key":"bibr2-03331024241254517","doi-asserted-by":"publisher","DOI":"10.2174\/187152410791196404"},{"key":"bibr3-03331024241254517","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-021-10930-x"},{"key":"bibr4-03331024241254517","volume":"360","author":"Adelborg K","year":"2018","journal-title":"BMJ (Clinical Research 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