{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T14:43:14Z","timestamp":1793889794328,"version":"4.8.0"},"reference-count":18,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Real-world data on the effectiveness and safety of lasmiditan, a new medication for acute migraine attacks, is necessary.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a prospective, observational, multi-center, real-world study. A total of 48 patients with migraine (44 females, 44.6\u2009\u00b1\u200912.9 years old) were included in this study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty-three patients (47.9%) reported they were headache-free two hours after taking lasmiditan and were categorized into the responder group. In total, 44 patients (91.7%) experienced at least one side effect within two hours of taking the medication. Dizziness, somnolence, malaise, nausea, and palpitations were reported by 56.3% (n\u2009=\u200927), 45.8% (n\u2009=\u200922), 37.5% (n\u2009=\u200918), 20.8% (n\u2009=\u200910), and 14.6% (n\u2009=\u20097) of patients respectively. Of 48 patients, 20 (41.7%) indicated that they preferred lasmiditan to their previous acute treatment. There were no predictive factors for efficacy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This real-world study demonstrated the efficacy and safety of lasmiditan. More than 90% of patients experienced side effects from lasmiditan. Approximately 40% of patients preferred lasmiditan despite the occurrence of side effects.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03331024241258695","type":"journal-article","created":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T03:38:37Z","timestamp":1718077117000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Efficacy and tolerability of 100\u2005mg of lasmiditan for migraine: A multi-center, prospective observational real-world study in Japan"],"prefix":"10.1177","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6976-1081","authenticated-orcid":false,"given":"Ryotaro","family":"Ishii","sequence":"first","affiliation":[{"name":"Department of Neurology, Kyoto Prefectural University of Medicine, Kyoto, Japan"},{"name":"Department of Neurology, Kyoto Okamoto Memorial Hospital, \rKyoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Ishizuchi","sequence":"additional","affiliation":[{"name":"Department of Neurology, Keio University School of Medicine, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narumi","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Neurology, Keio University School of Medicine, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryosuke","family":"Fukazawa","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kyoto Prefectural University of Medicine, Kyoto, Japan"},{"name":"Department of Neurology, Saiseikai Shiga Hospital, Shiga, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meesha","family":"Trivedi","sequence":"additional","affiliation":[{"name":"Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Nakahara","sequence":"additional","affiliation":[{"name":"Department of Neurology, Keio University School of Medicine, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsubasa","family":"Takizawa","sequence":"additional","affiliation":[{"name":"Department of Neurology, Keio University School of Medicine, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,6,11]]},"reference":[{"key":"bibr1-03331024241258695","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-2982.1997.1701015.x"},{"key":"bibr2-03331024241258695","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2004.04004.x"},{"key":"bibr3-03331024241258695","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-019-1012-1"},{"key":"bibr4-03331024241258695","doi-asserted-by":"publisher","DOI":"10.1177\/0333102410370873"},{"key":"bibr5-03331024241258695","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awz134"},{"key":"bibr6-03331024241258695","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000006641"},{"key":"bibr7-03331024241258695","doi-asserted-by":"publisher","DOI":"10.1111\/head.14122"},{"key":"bibr8-03331024241258695","doi-asserted-by":"publisher","DOI":"10.1111\/head.13897"},{"key":"bibr9-03331024241258695","doi-asserted-by":"crossref","first-page":"5274","DOI":"10.1007\/s12325-022-02289-w","volume":"39","author":"Takeshima T","year":"2022","journal-title":"Adv 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