{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T16:02:21Z","timestamp":1791820941401,"version":"4.3.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014476","name":"Pfizer Pharmaceuticals","doi-asserted-by":"publisher","award":["---"],"award-info":[{"award-number":["---"]}],"id":[{"id":"10.13039\/100014476","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013327","name":"H. Lundbeck A\/S","doi-asserted-by":"publisher","award":["---"],"award-info":[{"award-number":["---"]}],"id":[{"id":"10.13039\/501100013327","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006676","name":"Lilly Deutschland","doi-asserted-by":"publisher","award":["---"],"award-info":[{"award-number":["---"]}],"id":[{"id":"10.13039\/100006676","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008792","name":"Novartis Pharma","doi-asserted-by":"publisher","award":["---"],"award-info":[{"award-number":["---"]}],"id":[{"id":"10.13039\/100008792","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006259","name":"Teva Pharmaceutical Industries","doi-asserted-by":"publisher","award":["---"],"award-info":[{"award-number":["---"]}],"id":[{"id":"10.13039\/100006259","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The Migraine Disability Assessment (MIDAS) is widely used. However, there are limited data on how much a reduction in the MIDAS score indicates a change that matters to the patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data from the DMKG (i.e. German Migraine and Headache Society) Headache Registry were used to determine the minimal important difference (MID) of the MIDAS, using the Patient Global Impression of Change (PGIC) as anchor and applying average change and receiver operating characteristic curve methods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In total, 1218 adult migraine patients (85.6% female, 40.2\u2009\u00b1\u200912.8 years, baseline MIDAS 44.2\u2009\u00b1\u200947.4, follow-up MIDAS 36.5\u2009\u00b1\u200945.3) were included. For patients with baseline MIDAS &gt;20 (MIDAS grade IV, n\u2009=\u2009757), different methods using PGIC \u201csomewhat improved\u201d as anchor yielded percent change MIDs of the MIDAS between \u221229.4% and \u221233.2%. For baseline MIDAS between 6 and 20 (grades II and III, n\u2009=\u2009334), using PGIC \u201cmuch improved\u201d as anchor, difference change MIDs were between \u22123.5 and \u22124.5 points.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Based on the above results, we estimated the MID of the MIDAS at \u221230% for patients with a baseline MIDAS &gt;20, and at \u22124 points for those with a baseline MIDAS of 6\u201320, for a tertiary headache care population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>The DMKG Headache Registry is registered with the German Clinical Trials Register (DRKS 00021081).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03331024241261077","type":"journal-article","created":{"date-parts":[[2024,7,21]],"date-time":"2024-07-21T09:51:10Z","timestamp":1721555470000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Minimal important difference of the Migraine Disability Assessment (MIDAS): Longitudinal data from the DMKG Headache Registry"],"prefix":"10.1177","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9510-7158","authenticated-orcid":false,"given":"Ruth","family":"Ruscheweyh","sequence":"first","affiliation":[{"name":"Department of Neurology, LMU University Hospital, LMU Munich, Munich, Germany"},{"name":"German Migraine and Headache Society, Frankfurt, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie","family":"F\u00f6rderreuther","sequence":"additional","affiliation":[{"name":"Department of Neurology, LMU University Hospital, LMU Munich, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Freilinger","sequence":"additional","affiliation":[{"name":"Department of Neurology, Klinikum Passau, Passau, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charly","family":"Gaul","sequence":"additional","affiliation":[{"name":"Headache Center Frankfurt, Frankfurt, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0995-5482","authenticated-orcid":false,"given":"Gudrun","family":"Go\u00dfrau","sequence":"additional","affiliation":[{"name":"Interdisciplinary Pain Center, University Hospital and Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim Patrick","family":"J\u00fcrgens","sequence":"additional","affiliation":[{"name":"Department of Neurology, Headache Center North-East, University Medical Center Rostock, Rostock, Germany"},{"name":"Department of Neurology, KMG Klinikum G\u00fcstrow, G\u00fcstrow, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torsten","family":"Kraya","sequence":"additional","affiliation":[{"name":"Department of Neurology, Hospital Sankt Georg Leipzig gGmbH, Leipzig, Germany"},{"name":"Department of Neurology, Headache Center Halle, University Hospital Halle, Halle, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Neeb","sequence":"additional","affiliation":[{"name":"Helios Global Health, Berlin, Germany"},{"name":"Department of Neurology, Charit\u00e9 Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Ruschil","sequence":"additional","affiliation":[{"name":"Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University Hospital Tuebingen, Tuebingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9742-6080","authenticated-orcid":false,"given":"J\u00f6rg","family":"Scheidt","sequence":"additional","affiliation":[{"name":"Institute for Information Systems, University of Applied Sciences Hof, Hof, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Dresler","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Psychotherapy, Tuebingen Center for Mental Health, University Hospital Tuebingen, Tuebingen, Germany"},{"name":"German Center for Mental Health (DZPG), Partner Site Tuebingen, Tuebingen, Germany"},{"name":"LEAD Graduate School & Research Network, University of Tuebingen, Tuebingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,7,21]]},"reference":[{"key":"bibr1-03331024241261077","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.53.5.988"},{"key":"bibr2-03331024241261077","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18010246"},{"key":"bibr3-03331024241261077","doi-asserted-by":"publisher","DOI":"10.1177\/0333102420941839"},{"key":"bibr4-03331024241261077","doi-asserted-by":"publisher","DOI":"10.1177\/0333102418758283"},{"key":"bibr5-03331024241261077","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(15)00249-5"},{"key":"bibr6-03331024241261077","doi-asserted-by":"publisher","DOI":"10.1177\/0333102418789072"},{"key":"bibr7-03331024241261077","doi-asserted-by":"publisher","DOI":"10.1016\/0197-2456(89)90005-6"},{"key":"bibr8-03331024241261077","doi-asserted-by":"publisher","DOI":"10.4065\/77.4.371"},{"key":"bibr9-03331024241261077","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-021-01339-y"},{"key":"bibr10-03331024241261077","volume":"57","author":"Lipton RB","year":"2017","journal-title":"Headache (Abstracts AHS 2017)"},{"key":"bibr11-03331024241261077","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2007.03.012"},{"key":"bibr12-03331024241261077","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-022-01447-3"},{"key":"bibr13-03331024241261077","doi-asserted-by":"publisher","DOI":"10.1177\/0333102417738202"},{"key":"bibr14-03331024241261077","unstructured":"Guy W.\n                      ECDEU assessment manual for psychopharmacology\n                      . Rockville, MD: US Department of Health, Education, and Welfare, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration. National Institute of Mental Health, Psychopharmacology Research Branch, Division of Extramural Research Programs, 1976."},{"key":"bibr15-03331024241261077","doi-asserted-by":"publisher","DOI":"10.1177\/03635465231152484"},{"key":"bibr16-03331024241261077","doi-asserted-by":"publisher","DOI":"10.1186\/s12955-020-01344-w"},{"key":"bibr17-03331024241261077","doi-asserted-by":"publisher","DOI":"10.1586\/erp.11.9"},{"key":"bibr18-03331024241261077","doi-asserted-by":"publisher","DOI":"10.4097\/kja.21209"},{"key":"bibr19-03331024241261077","doi-asserted-by":"publisher","DOI":"10.1111\/head.14153"},{"key":"bibr20-03331024241261077","doi-asserted-by":"crossref","unstructured":"Diener H-C, F\u00f6rderreuther S, Kropp P.\n                      Therapie der Migr\u00e4neattacke und Prophylaxe der Migr\u00e4ne, S1-Leitlinie, 2022, DGN und DMKG\n                      , www.dgn.org\/leitlinien (accessed 30 January 2023).","DOI":"10.1007\/s42451-023-00550-2"},{"key":"bibr21-03331024241261077","doi-asserted-by":"publisher","DOI":"10.1111\/head.13946"}],"container-title":["Cephalalgia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03331024241261077","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03331024241261077","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03331024241261077","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:46:24Z","timestamp":1777387584000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03331024241261077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":21,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1177\/03331024241261077"],"URL":"https:\/\/doi.org\/10.1177\/03331024241261077","relation":{},"ISSN":["0333-1024","1468-2982"],"issn-type":[{"value":"0333-1024","type":"print"},{"value":"1468-2982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7]]},"article-number":"03331024241261077"}}