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The CT group showed a higher prevalence of personality disorders (PDs), particularly Cluster B (12% vs. 4%) and Cluster C (60% vs. 34%), as well as psychopathologies (94% vs. 75%);\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.001). The CT group also exhibited greater anxiety, depression, alexithymia and exposure to current stressful life events (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.001). CT participants were more frequently women, had an earlier migraine onset and a higher intake of acute medications. In the multivariate analysis, only Cluster C PDs (i.e., obsessive\u2013compulsive PD), psychopathologies (i.e., anxiety disorders), stressful life events, difficulty identifying feelings (alexithymia), and female sex remained significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      CT is associated with psychological comorbidities, an earlier onset of migraine and a higher intake of acute medications, leading to a more complex migraine phenotype\n                      <jats:bold>.<\/jats:bold>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03331024251358503","type":"journal-article","created":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T07:02:56Z","timestamp":1753945376000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Childhood traumas delineate a distinct psychological and clinical profile in adults with migraine: The hidden burden"],"prefix":"10.1177","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0151-3962","authenticated-orcid":false,"given":"Sara","family":"Bottiroli","sequence":"first","affiliation":[{"name":"University of Pavia"},{"name":"Mondino Foundation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6034-9288","authenticated-orcid":false,"given":"Martina","family":"Cangelosi","sequence":"additional","affiliation":[{"name":"University of Pavia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Allena","sequence":"additional","affiliation":[{"name":"Mondino Foundation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9415-4948","authenticated-orcid":false,"given":"Roberto De","family":"Icco","sequence":"additional","affiliation":[{"name":"University of Pavia"},{"name":"Mondino Foundation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6355-7947","authenticated-orcid":false,"given":"Daniele","family":"Martinelli","sequence":"additional","affiliation":[{"name":"Mondino Foundation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0117-7126","authenticated-orcid":false,"given":"Gloria","family":"Vaghi","sequence":"additional","affiliation":[{"name":"University of Pavia"},{"name":"Mondino Foundation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Guaschino","sequence":"additional","affiliation":[{"name":"Mondino Foundation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natascia","family":"Ghiotto","sequence":"additional","affiliation":[{"name":"Mondino Foundation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8257-2886","authenticated-orcid":false,"given":"Grazia","family":"Sances","sequence":"additional","affiliation":[{"name":"Mondino Foundation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1513-2113","authenticated-orcid":false,"given":"Cristina","family":"Tassorelli","sequence":"additional","affiliation":[{"name":"University of Pavia"},{"name":"Mondino Foundation"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,7,31]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30085-1"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-005-0416-7"},{"key":"e_1_3_2_4_2","first-page":"1","article-title":"Applying a biopsychosocial model to migraine: rationale and clinical implications","volume":"23","author":"Rosignoli C","year":"2022","unstructured":"Rosignoli C, Ornello R, Onofri A, et al. 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