{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:21:09Z","timestamp":1777490469766,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100003554","name":"Lundbeck Foundation","doi-asserted-by":"publisher","award":["R310-2018-3711"],"award-info":[{"award-number":["R310-2018-3711"]}],"id":[{"id":"10.13039\/501100003554","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013327","name":"H. Lundbeck A\/S","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013327","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      The HEAD-WINd\n                      <jats:sup>\u00ae<\/jats:sup>\n                      study was designed to examine the burden, characteristics and lived experiences of headache disorders in the Danish adult population. By integrating data from surveys, a smartphone application, and national health and social registries, the study addresses limitations of prior epidemiological research.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A random sample of Danish residents aged 18\u201375\u00a0years were invited to participate (\u201cbase population\u201d). Two nested cohorts were recruited using a population-based approach: (i) a survey cohort consisting of individuals reporting active headache disorders (\u201cheadache population\u201d) and (ii) a smartphone application cohort, derived from the headache population, which was followed longitudinally for 12\u00a0weeks. Data from these cohorts were enriched with data from national health and social registries, including information on medication use, hospital records, socioeconomic status and healthcare utilization. An adapted version of the Headache-Attributed Restriction, Disability, Social Handicap and Impaired Participation (HARDSHIP) questionnaire was used to classify multiple headache disorders and assess headache-attributed burden.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 100,030 invited individuals, 28,617 (28.6%) completed the general survey. Among them, 15,571 (54.4%) reported experiencing headache in the preceding year; 14,074 (90.4%) completed the headache-specific survey. In total, 663 individuals (4.7%) participated in the app-based longitudinal study. The mean\u00a0\u00b1\u00a0SD participant age was 53.2\u00a0\u00b1\u00a015.5\u00a0years, 57.4% were women and the mean\u00a0\u00b1\u00a0SD body mass index was 26.8\u00a0\u00b1\u00a07.4\u2005kg\/m\u00b2.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      HEAD-WINd\n                      <jats:sup>\u00ae<\/jats:sup>\n                      has established a comprehensive, population-based cohort of Danish residents, including individuals both with and without headache disorders. This resource provides a framework for generating population-level insights into the burden and management of headache disorders.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03331024251404430","type":"journal-article","created":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T11:27:31Z","timestamp":1769599651000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["HEAD-WINd\n                    <sup>\u00ae<\/sup>\n                    : A nationwide cohort study of headache disorders in danish adults using survey, smartphone and registry data"],"prefix":"10.1177","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-3662-5582","authenticated-orcid":false,"given":"Thien Phu","family":"Do","sequence":"first","affiliation":[{"name":"Copenhagen University Hospital\u00a0\u2013\u00a0Rigshospitalet"},{"name":"Danish Knowledge Center on Headache Disorders, Copenhagen University Hospital\u00a0\u2013\u00a0Rigshospitalet, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0538-1204","authenticated-orcid":false,"given":"Signe Marie","family":"Aagaard","sequence":"additional","affiliation":[{"name":"Copenhagen University Hospital\u00a0\u2013\u00a0Rigshospitalet"},{"name":"Danish Knowledge Center on Headache Disorders, Copenhagen University Hospital\u00a0\u2013\u00a0Rigshospitalet, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6268-727X","authenticated-orcid":false,"given":"H\u00e5kan","family":"Ashina","sequence":"additional","affiliation":[{"name":"Copenhagen University Hospital\u00a0\u2013\u00a0Rigshospitalet"},{"name":"Translational Research Center, Copenhagen University Hospital \u2013 Rigshospitalet, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy J.","family":"Steiner","sequence":"additional","affiliation":[{"name":"Copenhagen University Hospital\u00a0\u2013\u00a0Rigshospitalet"},{"name":"NorHead, Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway"},{"name":"Division of Brain Sciences, Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arun","family":"Micheelsen","sequence":"additional","affiliation":[{"name":"H. 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