{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T22:53:28Z","timestamp":1782168808009,"version":"3.54.5"},"reference-count":25,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Lilly, Teva, Novartis, Pfizer, Lundbeck","award":["N\/A. See text in manuscript under \"funding\""],"award-info":[{"award-number":["N\/A. See text in manuscript under \"funding\""]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>It has long been proposed that some individuals with migraine are especially prone to experience headache on weekends, however, results have been contradictory. Electronic headache diaries offer the possibility to analyze this question more thoroughly in larger populations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Two non-overlapping samples of individuals with migraine from the DMKG-App electronic headache diary were investigated. Cluster analysis and logistic regression were performed to study existence, prevalence and predictive factors of weekend headache.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We included 1793 and 5840 patients with \u226535 headache day entries in the two samples (\u201cregistry sample\u201d and \u201capp-only sample\u201d), respectively. In both samples, cluster analysis identified a cluster of patients with headache occurring preferably on weekends, accounting for 14\u201315% of all patients, and 18% of individuals with episodic migraine. Compared to the three other clusters identified (an early week cluster, a midweek cluster and a flat cluster without preference for a specific day), the weekend cluster was more frequent in working patients (p\u2009&lt;\u20090.001, OR = 3.57 to 3.97) and in patients with lower headache frequencies (p\u2009&lt;\u20090.001, OR = 0.86). A small association with older age (p\u2009&lt;\u20090.001, OR = 1.01) was limited to the app-only sample. Longitudinal analysis showed that headache patterns of single patients were variable over time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Results from two large samples corroborate that there is a subgroup of individuals with migraine prone to weekend headache. Association with working status supports the notion that release from stress could be a trigger factor in these patients, although change in sleep, caffeine and alcohol intake and other factors might also contribute.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03331024261444664","type":"journal-article","created":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T08:52:58Z","timestamp":1781772778000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Weekend headache in migraine \u2013 fact or fiction? An observational study from DMKG-app data"],"prefix":"10.1177","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9510-7158","authenticated-orcid":false,"given":"Ruth","family":"Ruscheweyh","sequence":"first","affiliation":[{"name":"LMU University Hospital, LMU Munich"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Dresler","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Psychotherapy, Tuebingen Center for Mental Health, University Hospital Tuebingen, Tuebingen, Germany"},{"name":"German Center for Mental Health (DZPG), Partner Site Tuebingen, Tuebingen, Germany"},{"name":"LEAD Graduate School &amp; Research Network, University of Tuebingen, Tuebingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gudrun","family":"Gossrau","sequence":"additional","affiliation":[{"name":"University Hospital and Faculty of Medicine Carl Gustav Carus, TU Dresden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torsten","family":"Kraya","sequence":"additional","affiliation":[{"name":"Hospital Sankt Georg Leipzig gGmbH"},{"name":"Headache Center Halle, Department of Neurology, University Hospital Halle, Halle, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Neeb","sequence":"additional","affiliation":[{"name":"University Hospital Brandenburg an der Havel, Brandenburg Medical School Theodor Fontane"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9758-1494","authenticated-orcid":false,"given":"Bianca","family":"Raffaelli","sequence":"additional","affiliation":[{"name":"Charit\u00e9-Universit\u00e4tsmedizin Berlin, Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t zu Berlin"},{"name":"Clinician Scientist Program, Berlin Institute of Health (BIH), Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1442-9997","authenticated-orcid":false,"given":"Victoria","family":"Ruschil","sequence":"additional","affiliation":[{"name":"University Hospital Tuebingen"},{"name":"Center of rare diseases, University Hospital Tuebingen, Tuebingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9742-6080","authenticated-orcid":false,"given":"J\u00f6rg","family":"Scheidt","sequence":"additional","affiliation":[{"name":"University of Applied Sciences Hof"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,6,18]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.1999.3901011.x"},{"key":"e_1_3_4_3_2","volume-title":"Headaches and other head pains","author":"Wolff H.","year":"1980","unstructured":"Wolff H. 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