{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:08:45Z","timestamp":1777489725868,"version":"3.51.4"},"reference-count":5,"publisher":"SAGE Publications","issue":"1_suppl","license":[{"start":{"date-parts":[[1983,8,1]],"date-time":"1983-08-01T00:00:00Z","timestamp":428544000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[1983,8]]},"abstract":"<jats:p>The present study takes into consideration some of the symptoms comprised in the Periodic Syndrome. These include motion-sickness, cyclic vomiting, recurrent abdominal pains and paroxysmal vertigo. Particular consideration is given to the chronological and long-term aspects of such symptoms. Among 247 migraine sufferers in the pediatric age group, 173 subjects who complained of at least one of these symptoms were chosen. Results of the data show that motion-sickness is the first to manifest itself (mean age of onset 2 years), and has a tendency to continue into the headache period; cyclic vomiting appears in the third year of life, and terminates sooner than the other symptoms. At the mean age of five years abdominal pains start, and at seven, paroxysmal vertigo. Headache is the final symptom in this group. The sequentiality of such disturbances in each subject leads to the assumption that the Periodic Syndrome is the expression of a single disorder which manifests itself polymorphously as a rather precisely timed process.<\/jats:p>\n                  <jats:p>\n                    Parmi les sympt\u00f4mes qui constituent le syndrome periodique de l'enfance, nous prenons en consid\u00e9ration, dans cette \u00e9tude, le mal d'auto, les vomissements cycliques, les douleurs abdominales r\u00e9currentes et les vertiges paroxystiques; nous en consid\u00e9rons particuli\u00e8rement les aspects chronologiques et l'\u00e9volution \u00e0 long terme. Il s'agit de 173 sujets, choisis parmi 247 migraineux en \u00e2ge \u00e9volutif, qui ont pr\u00e9sent\u00e9 au moins un des sympt\u00f4mes que nous avons \u00e9tudi\u00e9s. L'analyse des donn\u00e9es r\u00e9v\u00e8le que le mal d'auto est le premier qui se manifeste (au cours de la 2\n                    <jats:sup>\u00e8Me<\/jats:sup>\n                    ann\u00e9e) et qu'il tend \u00e0 continuer au-del\u00e0 du moment o\u00f9 apparait la c\u00e9phal\u00e9e; au cours de la 3\n                    <jats:sup>eMe<\/jats:sup>\n                    ann\u00e9e apparaissent les vomissements cycliques cui cessent plus t\u00f4t que les autres troubles; par la suite, vers l'\u00e2ge de 5 ans, commencent les douleurs abdominales et vers 7 ans les vertiges paroxystiques; enfin apparait la c\u00e9phal\u00e9e. L'observation de la s\u00e9quence de ces troubles chez les diff\u00e9rents sujets nous am\u00e8ne \u00e0 penser que le Syndrome p\u00e9riodique est l'expression d'un potentiel pathog\u00e8ne unique qui s'exprime \u00e0 travers des aspects polymorphes selon une s\u00e9quence temporelle assez pr\u00e9cise.\n                  <\/jats:p>\n                  <jats:p>Fra i sintomi che costituiscono la Sindrome periodica dell'infanzia, nel presente studio prendiamo in esame il mal d'auto, i vomiti ciclici, i dolori addominali ricorrenti e le vertigini parossistiche, considerandone in particolare gli aspetti cronologici e di evoluzione a lungo termine. Si tratta di 173 soggetti, scelti fra 247 emicranici in et\u00e0 evolutiva che hanno lamentato almeno uno dei sintomi da noi considerati. Dall'analisi dei dati emerge che il mal d'auto si manifesta per primo (Il anno di vita) e tende a protrarsi oltre il momento d'insorgenza della cefalea; nel III anno compaiono i vomiti ciclici che si estinguono pi\u00f9 precocemente degli altri disturbi; successivamente, verso i 5 anni, iniziano i dolori addominali e verso i 7 anni le vertigini parossistiche. Infine compare la cefalea. L'osservazione della sequenzialit\u00e0 di tali disturbi nei singoli soggetti ci fa pensare che la Sindrome periodica sia l'espressione di un unico potenziale patogeno che si estrinseca in aspetti polimorfi con una sequenza temporale abbastanza precisa.<\/jats:p>","DOI":"10.1177\/03331024830030s112","type":"journal-article","created":{"date-parts":[[2017,7,17]],"date-time":"2017-07-17T03:43:56Z","timestamp":1500263036000},"page":"91-93","source":"Crossref","is-referenced-by-count":9,"title":["The periodic syndrome in pediatric migraine sufferers"],"prefix":"10.1177","volume":"3","author":[{"given":"Giovanni","family":"Lanzi","sequence":"first","affiliation":[{"name":"Department of Child Neuropsychiatry, University of Pavia, Via Palestro 3, 27100 Pavia, Italy;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umberto","family":"Balottin","sequence":"additional","affiliation":[{"name":"Department of Child Neuropsychiatry, University of Pavia, Via Palestro 3, 27100 Pavia, Italy;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Fazzi","sequence":"additional","affiliation":[{"name":"Department of Child Neuropsychiatry, University of Pavia, Via Palestro 3, 27100 Pavia, Italy;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca Burgio","family":"Rosano","sequence":"additional","affiliation":[{"name":"Department of Child Neuropsychiatry, University of Pavia, Via Palestro 3, 27100 Pavia, Italy;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1983,8,1]]},"reference":[{"key":"bibr1-03331024830030S112","first-page":"1","volume":"30","author":"Wyllie W G","year":"1933","journal-title":"Br J Child Dis"},{"key":"bibr2-03331024830030S112","volume-title":"La cefalea essenziale nell'et\u00e0 evolutiva.","author":"Lanzi G","year":"1980"},{"key":"bibr3-03331024830030S112","volume-title":"Background to migraine.","author":"Cockrane AL","year":"1970"},{"key":"bibr4-03331024830030S112","first-page":"187","volume-title":"Advances in neurology.","volume":"33","author":"Del Bene E","year":"1982"},{"key":"bibr5-03331024830030S112","first-page":"104","volume":"13","author":"Lanzi G","year":"1981","journal-title":"Gaslini"}],"container-title":["Cephalalgia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03331024830030S112","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03331024830030S112","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:44:26Z","timestamp":1777387466000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03331024830030S112"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,8]]},"references-count":5,"journal-issue":{"issue":"1_suppl","published-print":{"date-parts":[[1983,8]]}},"alternative-id":["10.1177\/03331024830030S112"],"URL":"https:\/\/doi.org\/10.1177\/03331024830030s112","relation":{},"ISSN":["0333-1024","1468-2982"],"issn-type":[{"value":"0333-1024","type":"print"},{"value":"1468-2982","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,8]]}}}