{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:08:56Z","timestamp":1777489736496,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"1_suppl","license":[{"start":{"date-parts":[[1983,8,1]],"date-time":"1983-08-01T00:00:00Z","timestamp":428544000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[1983,8]]},"abstract":"<jats:p>In this multicentric random double-blind study versus placebo, the therapeutic activity of timed-release dihydroergotamine preparation 10 mg\/per os\/day has been tested in 90 patients affected by common migraine. The drug presented a prophylactic effect on recurrent headache, mainly on night and awakening migraine. A low incidence of side-effects with no weight changes or other effects on physiologic events was registered.<\/jats:p>\n                  <jats:p>Les r\u00e9sultas obtenus dans cette \u00e9tude contr\u00f4l\u00e9e, en double aveugle, sur une serie de 90 malades porteurs de \u2018migraine commune\u2019, montre que la dihydroergotamine retard est active. Cette substance sembre r\u00e9ellment pr\u00e9venir les crises du r\u00e9veil et de la nuit. La tol\u00e9rance clinique a \u00e9t\u00e9 exellente.<\/jats:p>\n                  <jats:p>In questo studio multicentrico in doppio cieco randomizzato versus placebo \u00e8 stata valutata l'attivit\u00e0 terapeutica di una diidroergotamina a liberazione programmata (10 mg\/per os\/die) in 90 pazienti affetti da emicranie comune. Il farmaco ha dimostrato di possedere un effetto sulle cefalee ricorrenti e soprattutto sulla emicrania notturna e del risveglio. Sono state registrate una bassa incidenza di effetti collaterali e nessuna variazione del peso corporeo e di altri parametri fisiologici.<\/jats:p>","DOI":"10.1177\/03331024830030s124","type":"journal-article","created":{"date-parts":[[2017,7,17]],"date-time":"2017-07-17T03:43:56Z","timestamp":1500263036000},"page":"151-155","source":"Crossref","is-referenced-by-count":9,"title":["Ergot derivatives in the prophylaxis of migraine: a multicentric study with a timed-release dihydroergotamine formulation"],"prefix":"10.1177","volume":"3","author":[{"given":"N.","family":"Martucci","sequence":"first","affiliation":[{"name":"Headache Centres, University of L'Aquila, Parma, Pavia, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Manna","sequence":"additional","affiliation":[{"name":"Headache Centres, University of L'Aquila, Parma, Pavia, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Mattesi","sequence":"additional","affiliation":[{"name":"Headache Centres, University of L'Aquila, Parma, Pavia, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Troiani","sequence":"additional","affiliation":[{"name":"Headache Centres, University of L'Aquila, Parma, Pavia, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. C.","family":"Manzoni","sequence":"additional","affiliation":[{"name":"Headache Centres, University of L'Aquila, Parma, Pavia, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Lanfranchi","sequence":"additional","affiliation":[{"name":"Headache Centres, University of L'Aquila, Parma, Pavia, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Bono","sequence":"additional","affiliation":[{"name":"Headache Centres, University of L'Aquila, Parma, Pavia, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Micieli","sequence":"additional","affiliation":[{"name":"Headache Centres, University of L'Aquila, Parma, Pavia, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1983,8,1]]},"reference":[{"key":"bibr1-03331024830030S124","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.1979.hed1903133.x"},{"key":"bibr2-03331024830030S124","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.1976.hed1605226.x"},{"key":"bibr3-03331024830030S124","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.1978.hed1802095.x"},{"key":"bibr4-03331024830030S124","first-page":"325","volume-title":"Advances in neurology.","volume":"33","author":"Horowski R","year":"1982"},{"key":"bibr5-03331024830030S124","first-page":"763","volume":"29","author":"Johnson A M","year":"1973","journal-title":"Experientia"},{"key":"bibr6-03331024830030S124","first-page":"173","volume-title":"Advances in neurology.","volume":"33","author":"Polleri A","year":"1982"},{"key":"bibr7-03331024830030S124","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.1979.hed1905273.x"},{"key":"bibr8-03331024830030S124","first-page":"385","volume":"10","author":"Loew D M","year":"1979","journal-title":"J Pharmacol (Paris)"},{"key":"bibr9-03331024830030S124","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-66775-6_3"},{"key":"bibr10-03331024830030S124","first-page":"343","volume-title":"Advances in neurology.","volume":"33","author":"M\u00fcller-Schwainitzer E","year":"1982"},{"key":"bibr11-03331024830030S124","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.1981.tb00004.x"},{"key":"bibr12-03331024830030S124","first-page":"2617","volume":"29","author":"Boudouresque J","year":"1978","journal-title":"La Vie M\u00e9dicale"},{"key":"bibr13-03331024830030S124","author":"Aylward M","year":"1982","journal-title":"Simbec Research Laboratories Limited"},{"key":"bibr14-03331024830030S124","first-page":"15","volume":"3","author":"Cremont F C","year":"1979","journal-title":"Medecin du Nord et d l'Est"},{"key":"bibr15-03331024830030S124","first-page":"2088","volume":"16","author":"Dauverchain J","year":"1980","journal-title":"Lyon M\u00e9dical Medicine du Sud-Est"},{"key":"bibr16-03331024830030S124","first-page":"91","volume":"13","author":"Flamant M P","year":"1980","journal-title":"Bourdeux Med"},{"key":"bibr17-03331024830030S124","first-page":"3","volume":"8","author":"Micieli G","year":"1982","journal-title":"Farmaci"},{"key":"bibr18-03331024830030S124","first-page":"1931","volume":"16","author":"Serratrice G","year":"1980","journal-title":"Lyon Medit Med Medec de Sud-Est"},{"key":"bibr19-03331024830030S124","first-page":"363","volume":"240","author":"Schott B","year":"1978","journal-title":"Lyon Medical"}],"container-title":["Cephalalgia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03331024830030S124","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03331024830030S124","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:44:28Z","timestamp":1777387468000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03331024830030S124"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,8]]},"references-count":19,"journal-issue":{"issue":"1_suppl","published-print":{"date-parts":[[1983,8]]}},"alternative-id":["10.1177\/03331024830030S124"],"URL":"https:\/\/doi.org\/10.1177\/03331024830030s124","relation":{},"ISSN":["0333-1024","1468-2982"],"issn-type":[{"value":"0333-1024","type":"print"},{"value":"1468-2982","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,8]]}}}