{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T18:46:40Z","timestamp":1791312400825,"version":"4.3.1"},"reference-count":32,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Sports Med"],"published-print":{"date-parts":[[2002,1]]},"abstract":"<jats:p>We evaluated the durability of autologous chondrocyte transplantation grafts in 61 patients treated for isolated cartilage defects on the femoral condyle or the patella and followed up for a mean of 7.4 years (range, 5 to 11). Durability was determined by comparing the clinical status at the long-term follow-up with that found 2 years after the transplantation. After 2 years, 50 of the 61 patients had good or excellent clinical results, and 51 of 61 had good or excellent results at 5 to 11 years later. Grafted areas from 11 of the patients were evaluated with an electromechanical indentation probe during a second-look arthroscopy procedure (mean follow-up, 54.3 months; range, 33 to 84); stiffness measurements were 90% or more of those of normal cartilage in eight patients. Eight of twelve 2-mm biopsy samples taken from these patients showed hyaline characteristics with safranin O staining and a homogeneous appearance in polarized light. Three fibrous and eight hyaline biopsy specimens stained positive to aggrecan and to cartilage oligomeric matrix protein. Hyaline-like specimens stained positive for type II collagen, and fibrous, for type I collagen. Autologous chondrocyte transplantation for the treatment of articular cartilage injuries has a durable outcome for as long as 11 years.<\/jats:p>","DOI":"10.1177\/03635465020300011601","type":"journal-article","created":{"date-parts":[[2017,7,19]],"date-time":"2017-07-19T00:42:31Z","timestamp":1500424951000},"page":"2-12","source":"Crossref","is-referenced-by-count":749,"title":["Autologous Chondrocyte Transplantation"],"prefix":"10.1177","volume":"30","author":[{"given":"Lars","family":"Peterson","sequence":"first","affiliation":[{"name":"Gothenburg Medical Center, Gothenburg University,Gothenburg, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mats","family":"Brittberg","sequence":"additional","affiliation":[{"name":"Kungsbacka Hospital, Gothenburg University,Gothenburg, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Illka","family":"Kiviranta","sequence":"additional","affiliation":[{"name":"Department of Surgery, Jyv\u00e4skyl\u00e4 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