{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T12:53:32Z","timestamp":1791723212014,"version":"4.3.4"},"reference-count":36,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2011,3,21]],"date-time":"2011-03-21T00:00:00Z","timestamp":1300665600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Sports Med"],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:p>Background: Platelet-rich plasma (PRP) has been shown to be a general stimulation for repair and 1-year results showed promising success percentages.<\/jats:p>\n                  <jats:p>Purpose: This trial was undertaken to determine the effectiveness of PRP compared with corticosteroid injections in patients with chronic lateral epicondylitis with a 2-year follow-up.<\/jats:p>\n                  <jats:p>Study Design: Randomized controlled trial; Level of evidence, 1.<\/jats:p>\n                  <jats:p>Methods: The trial was conducted in 2 Dutch teaching hospitals. One hundred patients with chronic lateral epicondylitis were randomly assigned to a leukocyte-enriched PRP group (n = 51) or the corticosteroid group (n = 49). Randomization and allocation to the trial group were carried out by a central computer system. Patients received either a corticosteroid injection or an autologous platelet concentrate injection through a peppering needling technique. The primary analysis included visual analog scale (VAS) pain scores and Disabilities of the Arm, Shoulder and Hand (DASH) outcome scores.<\/jats:p>\n                  <jats:p>Results: The PRP group was more often successfully treated than the corticosteroid group ( P &lt; .0001). Success was defined as a reduction of 25% on VAS or DASH scores without a reintervention after 2 years. When baseline VAS and DASH scores were compared with the scores at 2-year follow-up, both groups significantly improved across time (intention-to-treat principle). However, the DASH scores of the corticosteroid group returned to baseline levels, while those of the PRP group significantly improved (as-treated principle). There were no complications related to the use of PRP.<\/jats:p>\n                  <jats:p>Conclusion: Treatment of patients with chronic lateral epicondylitis with PRP reduces pain and increases function significantly, exceeding the effect of corticosteroid injection even after a follow-up of 2 years. Future decisions for application of PRP for lateral epicondylitis should be confirmed by further follow-up from this trial and should take into account possible costs and harms as well as benefits.<\/jats:p>","DOI":"10.1177\/0363546510397173","type":"journal-article","created":{"date-parts":[[2011,3,22]],"date-time":"2011-03-22T01:46:06Z","timestamp":1300758366000},"page":"1200-1208","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":459,"title":["Ongoing Positive Effect of Platelet-Rich Plasma Versus Corticosteroid Injection in Lateral Epicondylitis"],"prefix":"10.1177","volume":"39","author":[{"given":"Taco","family":"Gosens","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, St Elisabeth Hospital, Tilburg, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joost C.","family":"Peerbooms","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Haga Hospital, The Hague, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilbert","family":"van Laar","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Haga Hospital, The Hague, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenda L.","family":"den Oudsten","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, St Elisabeth Hospital, Tilburg, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2011,3,21]]},"reference":[{"key":"bibr1-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1080\/00016470410001708190"},{"issue":"405","key":"bibr2-0363546510397173","first-page":"209","volume":"46","author":"Assendelft WJ","year":"1996","journal-title":"Br J Gen Pract"},{"key":"bibr3-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1016\/S0894-1130(01)80043-0"},{"issue":"2","key":"bibr4-0363546510397173","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1002\/jor.20980","volume":"28","author":"Bosch G","year":"2010","journal-title":"J Orthop Res"},{"key":"bibr5-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibtech.2008.11.009"},{"key":"bibr6-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1053\/jhsu.2003.50041"},{"key":"bibr7-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-007-0296-x"},{"key":"bibr8-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-007-9293-x"},{"key":"bibr9-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2007.06.635"},{"key":"bibr10-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.319.7215.964"},{"key":"bibr11-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2003.05.002"},{"key":"bibr12-0363546510397173","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-199401000-00001"},{"key":"bibr13-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-939559"},{"key":"bibr14-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(98)90029-4"},{"key":"bibr15-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1177\/0363546506288850"},{"key":"bibr16-0363546510397173","doi-asserted-by":"publisher","DOI":"10.2165\/00007256-200333050-00004"},{"key":"bibr17-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1002\/jor.20054"},{"key":"bibr18-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-5919(20)30489-0"},{"key":"bibr19-0363546510397173","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-197961060-00005"},{"key":"bibr20-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1177\/0363546509355445"},{"key":"bibr21-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1002\/art.24396"},{"key":"bibr22-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1007\/s12178-008-9032-5"},{"key":"bibr23-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1001\/archfaci.7.3.163"},{"key":"bibr24-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2004.011312"},{"key":"bibr25-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1080\/07853890310004138"},{"key":"bibr26-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(01)00388-8"},{"issue":"10","key":"bibr27-0363546510397173","first-page":"2053","volume":"33","author":"Smidt N","year":"2006","journal-title":"J Rheumatol"},{"key":"bibr28-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)07811-X"},{"key":"bibr29-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/33.12.1166"},{"key":"bibr30-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1177\/0095399703258714"},{"issue":"4","key":"bibr31-0363546510397173","first-page":"443","volume":"73","author":"Thomas S","year":"2007","journal-title":"Acta Orthop Belg"},{"key":"bibr32-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1016\/S0894-1130(02)80006-0"},{"key":"bibr33-0363546510397173","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199307000-00010"},{"key":"bibr34-0363546510397173","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000195927.81845.46"},{"key":"bibr35-0363546510397173","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-143-11-200512060-00007"},{"issue":"3","key":"bibr36-0363546510397173","first-page":"227","volume":"9","author":"Wrotniak M","year":"2007","journal-title":"Ortop Traumatol Rehabil"}],"container-title":["The American Journal of Sports Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0363546510397173","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0363546510397173","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0363546510397173","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:43:20Z","timestamp":1777369400000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0363546510397173"}},"subtitle":["A Double-Blind Randomized Controlled Trial With 2-year Follow-up"],"short-title":[],"issued":{"date-parts":[[2011,3,21]]},"references-count":36,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["10.1177\/0363546510397173"],"URL":"https:\/\/doi.org\/10.1177\/0363546510397173","relation":{},"ISSN":["0363-5465","1552-3365"],"issn-type":[{"value":"0363-5465","type":"print"},{"value":"1552-3365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3,21]]}}}