{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:23:30Z","timestamp":1777389810173,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2015,3,29]],"date-time":"2015-03-29T00:00:00Z","timestamp":1427587200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Sports Med"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>In most treatment algorithms, osteochondral allograft (OCA) transplantation is regarded as an alternative salvage procedure when other, previous reparative treatments have failed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To compare the outcomes of a retrospective matched-pair cohort of (1) primary OCA transplantation and (2) OCA transplantation after failure of previous subchondral marrow stimulation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design:<\/jats:title>\n                    <jats:p>Cohort study; Level of evidence, 3.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      An OCA database was used to identify 46 knees that had OCA transplantation performed as a primary treatment (group 1) and 46 knees that underwent OCA transplantation after failure of previous subchondral marrow stimulation (group 2). All patients had a minimum of 2 years\u2019 follow-up. Patients in each group were matched for age (\u00b15 years), diagnosis (osteochondral lesion, degenerative chondral lesion, traumatic chondral injury), and graft size (small, &lt;5 cm\n                      <jats:sup>2<\/jats:sup>\n                      ; medium, 5-10 cm\n                      <jats:sup>2<\/jats:sup>\n                      ; large, &gt;10 cm\n                      <jats:sup>2<\/jats:sup>\n                      ). The groups had similar body mass indexes, sex distributions, and graft locations (femoral condyle, patella, and trochlea. The number and type of further surgeries after the OCA transplantation were assessed; failure was defined as any reoperation resulting in removal of the graft. Functional outcomes were evaluated by use of the modified Merle d\u2019Aubign\u00e9-Postel (18-point) scale, International Knee Documentation Committee (IKDC) subjective knee evaluation form, Knee injury and Osteoarthritis Outcomes Score (KOOS), and the Knee Society function (KS-F) scale. Patient satisfaction, according to a 5-point scale from \u201cextremely satisfied\u201d to \u201cdissatisfied,\u201d was recorded at the latest follow-up.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Eleven of 46 knees (24%) in group 1 had reoperations, compared with 20 of 46 knees (44%) in group 2 ( P = .04). The OCA was classified as a failure in 5 knees (11%) in group 1 and 7 knees (15%) in group 2 ( P = .53). At 10 years of follow-up, survivorship of the graft was 87.4% and 86% in groups 1 and 2, respectively. Both groups showed improvement in pain and function on all subjective scores from preoperatively to the latest follow-up (all P &lt; .001). Results showed that 87% of patients in group 1 and 97% in group 2 were \u201csatisfied\u201d or \u201cextremely satisfied\u201d with the OCA transplantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Favorable results were shown in both groups with significant improvement of functional scores and excellent survivorship. Despite the higher reoperation rate in the previously treated group, previous subchondral marrow stimulation did not adversely affect the survivorship and functional outcome of OCA transplantation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0363546514565770","type":"journal-article","created":{"date-parts":[[2015,3,29]],"date-time":"2015-03-29T20:12:01Z","timestamp":1427659921000},"page":"885-891","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":100,"title":["Fresh Osteochondral Allografts in the Knee"],"prefix":"10.1177","volume":"43","author":[{"given":"Guilherme C.","family":"Gracitelli","sequence":"first","affiliation":[{"name":"Shiley Center for Orthopaedic Research and Education at Scripps Clinic, La Jolla, California, USA"},{"name":"Department of Orthopaedic Surgery, Federal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gokhan","family":"Meric","sequence":"additional","affiliation":[{"name":"Shiley Center for Orthopaedic Research and Education at Scripps Clinic, La Jolla, California, USA"},{"name":"Department of Orthopaedic Surgery, Balikesir University, Balikesir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dustin T.","family":"Briggs","sequence":"additional","affiliation":[{"name":"Shiley Center for Orthopaedic Research and Education at Scripps Clinic, La Jolla, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pamela A.","family":"Pulido","sequence":"additional","affiliation":[{"name":"Shiley Center for Orthopaedic Research and Education at Scripps Clinic, La Jolla, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie C.","family":"McCauley","sequence":"additional","affiliation":[{"name":"Shiley Center for Orthopaedic Research and Education at Scripps Clinic, La Jolla, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Carlos","family":"Belloti","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Federal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William D.","family":"Bugbee","sequence":"additional","affiliation":[{"name":"Division of Orthopaedic Surgery, Scripps Clinic, La Jolla, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,3,29]]},"reference":[{"key":"bibr1-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1097\/JSM.0000000000000004"},{"key":"bibr2-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1177\/0363546513485931"},{"key":"bibr3-0363546514565770","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.L.00165"},{"key":"bibr4-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1016\/j.csm.2014.01.002"},{"key":"bibr5-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2012.12.002"},{"key":"bibr6-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199903000-00019"},{"key":"bibr7-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-8063(97)90124-9"},{"key":"bibr8-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2007.07.005"},{"key":"bibr9-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1177\/0363546512473258"},{"key":"bibr10-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1177\/0363546507299932"},{"key":"bibr11-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0b013e3181d9eea0"},{"key":"bibr12-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-010-1250-7"},{"key":"bibr13-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-008-0282-8"},{"key":"bibr14-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000165845.21735.05"},{"key":"bibr15-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1177\/0363546509352157"},{"key":"bibr16-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-198911000-00004"},{"key":"bibr17-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1177\/03635465010290051301"},{"key":"bibr18-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2006.05.003"},{"key":"bibr19-0363546514565770","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.H.00703"},{"key":"bibr20-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-012-2556-4"},{"key":"bibr21-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1177\/0363546506295178"},{"key":"bibr22-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1177\/0363546508330137"},{"key":"bibr23-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1177\/0363546508328414"},{"key":"bibr24-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1177\/0363546513516747"},{"key":"bibr25-0363546514565770","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.L.01695"},{"key":"bibr26-0363546514565770","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.1998.28.2.88"},{"key":"bibr27-0363546514565770","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-201402000-00007"},{"key":"bibr28-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1016\/j.otsr.2011.09.007"},{"key":"bibr29-0363546514565770","doi-asserted-by":"publisher","DOI":"10.1177\/0363546508322897"}],"container-title":["The American Journal of Sports Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0363546514565770","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0363546514565770","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0363546514565770","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:48:59Z","timestamp":1777369739000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0363546514565770"}},"subtitle":["Comparison of Primary Transplantation Versus Transplantation After Failure of Previous Subchondral Marrow Stimulation"],"short-title":[],"issued":{"date-parts":[[2015,3,29]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["10.1177\/0363546514565770"],"URL":"https:\/\/doi.org\/10.1177\/0363546514565770","relation":{},"ISSN":["0363-5465","1552-3365"],"issn-type":[{"value":"0363-5465","type":"print"},{"value":"1552-3365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,29]]}}}