{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T05:55:42Z","timestamp":1790142942031,"version":"4.0.1"},"reference-count":71,"publisher":"SAGE Publications","issue":"13","license":[{"start":{"date-parts":[[2017,8,14]],"date-time":"2017-08-14T00:00:00Z","timestamp":1502668800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Sports Med"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Platelet-rich plasma (PRP) has been applied as an adjunct to rotator cuff repair to improve tendon-bone healing and potentially reduce the incidence of subsequent tendon retears.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To investigate whether the midterm clinical and radiographic outcomes of arthroscopic supraspinatus repair are enhanced after repeated postoperative applications of PRP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design:<\/jats:title>\n                    <jats:p>Randomized controlled trial; Level of evidence, 1.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A total of 60 patients (30 control; 30 PRP) were initially randomized to receive 2 ultrasound-guided injections of PRP to the tendon repair site at 7 and 14 days after double-row arthroscopic supraspinatus repair or not. A total of 55 patients (91.7%) underwent a clinical review and magnetic resonance imaging (MRI) at a mean of 3.5 years after surgery (range, 36-51 months). Patient-reported outcome measures (PROMs) included the Constant score, Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH) questionnaire, Oxford Shoulder Score (OSS), and visual analog scale (VAS) for pain. Global rating of change (GRC) scale and patient satisfaction scores were evaluated. Structural integrity of the surgical repair was assessed via MRI using the Sugaya classification system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>At the midterm review, there was no difference between the groups for any of the PROMs. No differences between the groups were demonstrated for the subjective and range of motion subscales of the Constant score, although a significantly higher Constant strength subscale score was observed in the PRP group (3.3 points; 95% CI, 1.0-5.7; P = .006). There was no evidence for any group differences in MRI scores or retear rates, with 66.7% of PRP patients and 64.3% of control patients rated as Sugaya grade 1. Two control patients had symptomatic retears (both full thickness) within the first 16 weeks after surgery compared with 2 PRP patients, who suffered symptomatic retears (both partial thickness) between 16 weeks and a mean 3.5-year follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Significant postoperative clinical improvements and high levels of patient satisfaction were observed in patients at the midterm review after supraspinatus repair. While pain-free, maximal abduction strength was greater in the midterm after PRP treatment, repeated applications of PRP delivered at 7 and 14 days after surgery provided no additional benefit to tendon integrity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0363546517719048","type":"journal-article","created":{"date-parts":[[2017,8,14]],"date-time":"2017-08-14T16:07:47Z","timestamp":1502726867000},"page":"2965-2974","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":83,"title":["A Midterm Evaluation of Postoperative Platelet-Rich Plasma Injections on Arthroscopic Supraspinatus Repair: A Randomized Controlled Trial"],"prefix":"10.1177","volume":"45","author":[{"given":"Jay R.","family":"Ebert","sequence":"first","affiliation":[{"name":"School of Human Sciences, The University of Western Australia, Perth, Western Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Human Sciences, The University of Western Australia, Perth, Western Australia, Australia"},{"name":"Department of Orthopaedic Surgery, St John of God Subiaco Hospital, Perth, Western Australia, Australia"},{"name":"Department of Orthopaedic Surgery, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Smith","sequence":"additional","affiliation":[{"name":"School of Physiotherapy and Exercise Science and Curtin Health Innovation Research Institute, Curtin University, Perth, Western Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Nairn","sequence":"additional","affiliation":[{"name":"Perth Radiological Clinic, Perth, Western Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Breidahl","sequence":"additional","affiliation":[{"name":"Perth Radiological Clinic, Perth, Western Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming Hao","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Ackland","sequence":"additional","affiliation":[{"name":"School of Human Sciences, The University of Western Australia, Perth, Western Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,8,14]]},"reference":[{"issue":"2","key":"bibr1-0363546517719048","doi-asserted-by":"crossref","first-page":"211","DOI":"10.5312\/wjo.v6.i2.211","volume":"6","author":"Abtahi AM","year":"2015","journal-title":"World J Orthop"},{"issue":"1","key":"bibr2-0363546517719048","first-page":"25","volume":"79","author":"Antuna S","year":"2013","journal-title":"Acta Orthop Belg"},{"issue":"8","key":"bibr3-0363546517719048","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1016\/j.arthro.2011.06.010","volume":"27","author":"Barber A","year":"2011","journal-title":"Arthroscopy"},{"issue":"5","key":"bibr4-0363546517719048","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.arthro.2015.11.020","volume":"32","author":"Barber FA","year":"2016","journal-title":"Arthroscopy"},{"issue":"5","key":"bibr5-0363546517719048","first-page":"1038","volume":"87","author":"Beaton DE","year":"2005","journal-title":"J Bone Joint Surg Am"},{"key":"bibr6-0363546517719048","doi-asserted-by":"publisher","DOI":"10.1177\/0363546511424402"},{"issue":"6","key":"bibr7-0363546517719048","first-page":"1229","volume":"87","author":"Boileau P","year":"2005","journal-title":"J Bone Joint Surg Am"},{"issue":"12","key":"bibr8-0363546517719048","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.1016\/j.jse.2015.07.035","volume":"24","author":"Cai YZ","year":"2015","journal-title":"J Shoulder Elbow Surg"},{"issue":"6","key":"bibr9-0363546517719048","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/S1058-2746(98)90007-6","volume":"7","author":"Carpenter JE","year":"1998","journal-title":"J Shoulder Elbow Surg"},{"key":"bibr10-0363546517719048","doi-asserted-by":"publisher","DOI":"10.1177\/0363546510390780"},{"issue":"11","key":"bibr11-0363546517719048","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1016\/j.arthro.2012.03.007","volume":"28","author":"Chahal J","year":"2012","journal-title":"Arthroscopy"},{"issue":"4","key":"bibr12-0363546517719048","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.arthro.2013.12.018","volume":"30","author":"Charousset C","year":"2014","journal-title":"Arthroscopy"},{"issue":"2","key":"bibr13-0363546517719048","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.jse.2007.06.022","volume":"17","author":"Constant CR","year":"2008","journal-title":"J Shoulder Elbow Surg"},{"key":"bibr14-0363546517719048","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1097\/00003086-198701000-00023","volume":"214","author":"Constant CR","year":"1987","journal-title":"Clin Orthop Relat Res"},{"issue":"2","key":"bibr15-0363546517719048","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1067\/mse.2003.21","volume":"12","author":"Cummins CA","year":"2003","journal-title":"J Shoulder Elbow Surg"},{"issue":"1","key":"bibr16-0363546517719048","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.orthres.2004.05.007","volume":"23","author":"Dahlgren LA","year":"2005","journal-title":"J Orthop Res"},{"issue":"4","key":"bibr17-0363546517719048","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1302\/0301-620X.78B4.0780593","volume":"78","author":"Dawson J","year":"1996","journal-title":"J Bone Joint Surg Br"},{"issue":"6","key":"bibr18-0363546517719048","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1302\/0301-620X.83B6.0830877","volume":"83","author":"Dawson J","year":"2001","journal-title":"J Bone Joint Surg Br"},{"key":"bibr19-0363546517719048","doi-asserted-by":"publisher","DOI":"10.1177\/0363546511428866"},{"issue":"11","key":"bibr20-0363546517719048","doi-asserted-by":"crossref","first-page":"657","DOI":"10.5435\/00124635-201111000-00002","volume":"19","author":"Denard PJ","year":"2011","journal-title":"J Am Acad Orthop Surg"},{"issue":"10","key":"bibr21-0363546517719048","doi-asserted-by":"crossref","first-page":"583","DOI":"10.5435\/00124635-201110000-00002","volume":"19","author":"Edwards SL","year":"2011","journal-title":"J Am Acad Orthop Surg"},{"issue":"8","key":"bibr22-0363546517719048","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1016\/j.jse.2015.04.013","volume":"24","author":"Fermont AJ","year":"2015","journal-title":"J Shoulder Elbow Surg"},{"issue":"3","key":"bibr23-0363546517719048","doi-asserted-by":"crossref","first-page":"153","DOI":"10.2519\/jospt.2014.4832","volume":"44","author":"Fermont AJ","year":"2014","journal-title":"J Orthop Sports Phys Ther"},{"key":"bibr24-0363546517719048","doi-asserted-by":"publisher","DOI":"10.1177\/0363546516643716"},{"key":"bibr25-0363546517719048","doi-asserted-by":"publisher","DOI":"10.1177\/0363546516645518"},{"issue":"3","key":"bibr26-0363546517719048","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1148\/radiol.2015141544","volume":"276","author":"Fukawa T","year":"2015","journal-title":"Radiology"},{"issue":"2","key":"bibr27-0363546517719048","doi-asserted-by":"crossref","first-page":"219","DOI":"10.2106\/00004623-200402000-00002","volume":"86","author":"Galatz LM","year":"2004","journal-title":"J Bone Joint Surg Am"},{"issue":"7","key":"bibr28-0363546517719048","doi-asserted-by":"crossref","first-page":"2216","DOI":"10.1007\/s00167-015-3547-2","volume":"24","author":"Ganal E","year":"2016","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"issue":"10","key":"bibr29-0363546517719048","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1016\/j.arthro.2016.01.067","volume":"32","author":"Gasbarro G","year":"2016","journal-title":"Arthroscopy"},{"issue":"4","key":"bibr30-0363546517719048","doi-asserted-by":"crossref","first-page":"505","DOI":"10.2106\/00004623-200004000-00006","volume":"82","author":"Gerber C","year":"2000","journal-title":"J Bone Joint Surg Am"},{"issue":"6","key":"bibr31-0363546517719048","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.jse.2007.02.122","volume":"16","author":"Gerber C","year":"2007","journal-title":"J Shoulder Elbow Surg"},{"key":"bibr32-0363546517719048","doi-asserted-by":"publisher","DOI":"10.1177\/0363546506297539"},{"issue":"1","key":"bibr33-0363546517719048","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.csm.2008.09.002","volume":"28","author":"Gulotta LV","year":"2009","journal-title":"Clin Sports Med"},{"issue":"15","key":"bibr34-0363546517719048","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.2106\/JBJS.K.00394","volume":"94","author":"Gumina S","year":"2012","journal-title":"J Bone Joint Surg Am"},{"issue":"11","key":"bibr35-0363546517719048","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1016\/j.jse.2014.03.016","volume":"23","author":"Gumina S","year":"2014","journal-title":"J Shoulder Elbow Surg"},{"key":"bibr36-0363546517719048","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/1471-2474-7-44","volume":"7","author":"Gummesson C","year":"2006","journal-title":"BMC Musculoskelet Disord"},{"issue":"8","key":"bibr37-0363546517719048","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1007\/s00402-016-2499-4","volume":"136","author":"Gwinner C","year":"2016","journal-title":"Arch Orthop Trauma Surg"},{"key":"bibr38-0363546517719048","doi-asserted-by":"publisher","DOI":"10.1177\/1941738114548413"},{"issue":"3","key":"bibr39-0363546517719048","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.jse.2014.07.003","volume":"24","author":"Henseler JF","year":"2015","journal-title":"J Shoulder Elbow Surg"},{"issue":"9","key":"bibr40-0363546517719048","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1007\/s00264-014-2391-1","volume":"38","author":"Hernigou P","year":"2014","journal-title":"Int Orthop"},{"key":"bibr41-0363546517719048","doi-asserted-by":"publisher","DOI":"10.1177\/2325967116665595"},{"issue":"10","key":"bibr42-0363546517719048","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1038\/ni1501","volume":"8","author":"Jiang N","year":"2007","journal-title":"Nat Immunol"},{"key":"bibr43-0363546517719048","doi-asserted-by":"publisher","DOI":"10.1177\/0363546511413454"},{"key":"bibr44-0363546517719048","doi-asserted-by":"publisher","DOI":"10.1177\/0363546513497925"},{"issue":"3","key":"bibr45-0363546517719048","first-page":"472","volume":"88","author":"Jost B","year":"2006","journal-title":"J Bone Joint Surg Am"},{"issue":"4","key":"bibr46-0363546517719048","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S0004-9514(09)70015-7","volume":"55","author":"Kamper S","year":"2009","journal-title":"Aust J Physiother"},{"issue":"2","key":"bibr47-0363546517719048","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/s00256-016-2534-0","volume":"46","author":"Krepkin K","year":"2017","journal-title":"Skeletal Radiol"},{"issue":"2","key":"bibr48-0363546517719048","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.arthro.2009.11.015","volume":"26","author":"Lopez-Vidriero E","year":"2010","journal-title":"Arthroscopy"},{"key":"bibr49-0363546517719048","doi-asserted-by":"publisher","DOI":"10.1177\/0363546514541777"},{"issue":"2","key":"bibr50-0363546517719048","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.jse.2003.11.002","volume":"13","author":"Mallon WJ","year":"2004","journal-title":"J Shoulder Elbow Surg"},{"key":"bibr51-0363546517719048","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1308\/003588408X285964","volume":"90","author":"Olley LM","year":"2008","journal-title":"Ann R Coll Surg Engl"},{"issue":"8","key":"bibr52-0363546517719048","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1016\/j.jse.2016.01.036","volume":"25","author":"Pandey V","year":"2016","journal-title":"J Shoulder Elbow Surg"},{"issue":"4","key":"bibr53-0363546517719048","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.jse.2011.02.008","volume":"20","author":"Randelli P","year":"2011","journal-title":"J Shoulder Elbow Surg"},{"issue":"2","key":"bibr54-0363546517719048","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1302\/0301-620X.95B2.30246","volume":"95","author":"Robinson PM","year":"2013","journal-title":"Bone Joint J"},{"key":"bibr55-0363546517719048","doi-asserted-by":"publisher","DOI":"10.1177\/0363546512442924"},{"issue":"1","key":"bibr56-0363546517719048","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.arthro.2012.08.014","volume":"29","author":"Ruiz-Moneo P","year":"2013","journal-title":"Arthroscopy"},{"issue":"5","key":"bibr57-0363546517719048","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/j.arthro.2015.10.007","volume":"32","author":"Saltzman BM","year":"2016","journal-title":"Arthroscopy"},{"issue":"3","key":"bibr58-0363546517719048","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1136\/bjsm.2004.011312","volume":"38","author":"Scott A","year":"2004","journal-title":"Br J Sports Med"},{"issue":"1","key":"bibr59-0363546517719048","doi-asserted-by":"crossref","first-page":"10","DOI":"10.2106\/00004623-199501000-00002","volume":"77","author":"Sher JS","year":"1995","journal-title":"J Bone Joint Surg Am"},{"key":"bibr60-0363546517719048","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200705000-00006"},{"issue":"4","key":"bibr61-0363546517719048","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/S1058-2746(99)90148-9","volume":"8","author":"Tempelhof S","year":"1999","journal-title":"J Shoulder Elbow Surg"},{"key":"bibr62-0363546517719048","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/1749-799X-8-40","volume":"8","author":"van Kampen DA","year":"2013","journal-title":"J Orthop Surg Res"},{"key":"bibr63-0363546517719048","doi-asserted-by":"publisher","DOI":"10.1177\/0363546515572777"},{"issue":"2","key":"bibr64-0363546517719048","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.jse.2015.10.009","volume":"25","author":"Verhaegen F","year":"2016","journal-title":"J Shoulder Elbow Surg"},{"key":"bibr65-0363546517719048","doi-asserted-by":"publisher","DOI":"10.1177\/0363546515572602"},{"issue":"2","key":"bibr66-0363546517719048","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.arthro.2014.09.007","volume":"31","author":"Warth RJ","year":"2015","journal-title":"Arthroscopy"},{"key":"bibr67-0363546517719048","doi-asserted-by":"publisher","DOI":"10.1177\/0363546512467621"},{"issue":"4","key":"bibr68-0363546517719048","doi-asserted-by":"crossref","first-page":"101","DOI":"10.4103\/0973-6042.145232","volume":"8","author":"Werthel JD","year":"2014","journal-title":"Int J Shoulder Surg"},{"key":"bibr69-0363546517719048","doi-asserted-by":"crossref","first-page":"S198","DOI":"10.1016\/j.jse.2007.04.003","volume":"16","author":"Wurgler-Hauri CC","year":"2007","journal-title":"J Shoulder Elbow Surg"},{"issue":"2","key":"bibr70-0363546517719048","first-page":"191","volume":"50","author":"Zhang Z","year":"2016","journal-title":"Acta Orthop Traumatol Turc"},{"issue":"1","key":"bibr71-0363546517719048","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.arthro.2014.08.008","volume":"31","author":"Zhao JG","year":"2015","journal-title":"Arthroscopy"}],"container-title":["The American Journal of Sports Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0363546517719048","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0363546517719048","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0363546517719048","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:51:10Z","timestamp":1777369870000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1177\/0363546517719048"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,14]]},"references-count":71,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1177\/0363546517719048"],"URL":"https:\/\/doi.org\/10.1177\/0363546517719048","relation":{},"ISSN":["0363-5465","1552-3365"],"issn-type":[{"value":"0363-5465","type":"print"},{"value":"1552-3365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,14]]}}}