{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T21:42:00Z","timestamp":1788644520331,"version":"build-2803163510"},"reference-count":35,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2018,4,5]],"date-time":"2018-04-05T00:00:00Z","timestamp":1522886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Sports Med"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Clinically, onto-surface repair is commonly used for rotator cuff tears. The retear rate after rotator cuff repair (RCR) is relatively high, with failure occurring mostly at the tendon-bone connection site. For anterior cruciate ligament (ACL) reconstruction, into-tunnel reconstruction is commonly employed. The retear rate after ACL reconstruction is relatively low, with retears seldom occurring at the tendon-bone interface. No study on into-tunnel RCR has been conducted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Hypothesis:<\/jats:title>\n                    <jats:p>Into-tunnel RCR could promote fibrocartilage regeneration at the tendon-bone interface and has biomechanical advantage over onto-surface repair in a rabbit rotator cuff tear model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design:<\/jats:title>\n                    <jats:p>Controlled laboratory study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Thirty-six New Zealand White rabbits were used in this study. The supraspinatus tendons were cut from the footprint to create a rotator cuff tear on both shoulders. On one side, the supraspinatus was cut longitudinally into 2 halves, sutured, and pulled into 2 tunnels through the greater tuberosity (into-tunnel repair). On the other side, the tendon was reattached to the surface of the footprint with transosseous sutures (onto-surface repair). Twelve animals were sacrificed, of which 6 were used for a histological examination and the other 6 for biomechanical testing, at 4, 8, and 12 weeks, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The tendon-bone interface in the into-tunnel group showed a different healing pattern from that in the onto-surface group. In the former, most of the tendon tissue in the tunnel was replaced with newly generated fibrocartilage; the rest of the tendon fibers appeared in large bundles with direct connection to the bone. In the latter, fibrocartilage regeneration was seldom found at the tendon-bone interface; the tendon near the bone surface appeared as small fibrils. The biomechanical evaluation revealed a higher ultimate load ( P &lt; .001) and stiffness ( P &lt; .001) at the tendon-bone junction in the into-tunnel group than those in the onto-surface group at 12 weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>In a rabbit rotator cuff tear model, into-tunnel RCR could result in a different tendon-bone healing pattern, with obvious fibrocartilage regeneration at the interface and higher tendon-bone healing strength than that in onto-surface repair.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Relevance:<\/jats:title>\n                    <jats:p>New RCR patterns may be developed to improve the tendon-bone healing pattern and obtain better tendon-bone healing strength.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0363546518764685","type":"journal-article","created":{"date-parts":[[2018,4,5]],"date-time":"2018-04-05T22:21:13Z","timestamp":1522966873000},"page":"1711-1719","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":40,"title":["Into-Tunnel Repair Versus Onto-Surface Repair for Rotator Cuff Tears in a Rabbit Model"],"prefix":"10.1177","volume":"46","author":[{"given":"Xiaoxi","family":"Li","sequence":"first","affiliation":[{"name":"Department of Sports Medicine, Shanghai Sixth People\u2019s Hospital, Shanghai Jiao Tong University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine, Shanghai Sixth People\u2019s Hospital, Shanghai Jiao Tong University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine, Shanghai Sixth People\u2019s Hospital, Shanghai Jiao Tong University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine, Shanghai Sixth People\u2019s Hospital, Shanghai Jiao Tong University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinzhong","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine, Shanghai Sixth People\u2019s Hospital, Shanghai Jiao Tong University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,4,5]]},"reference":[{"key":"bibr1-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1016\/j.jse.2011.09.020"},{"issue":"6","key":"bibr2-0363546518764685","first-page":"1229","volume":"87","author":"Boileau P","year":"2005","journal-title":"J Bone Joint Surg Am"},{"key":"bibr3-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1177\/0363546510390780"},{"key":"bibr4-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1067\/mse.2003.21"},{"issue":"3","key":"bibr5-0363546518764685","first-page":"169","volume":"2","author":"Delaine-Smith RM","year":"2012","journal-title":"Muscles Ligaments Tendons J"},{"key":"bibr6-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-008-0584-0"},{"key":"bibr7-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tea.2012.0623"},{"key":"bibr8-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1177\/0363546509339582"},{"key":"bibr9-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1177\/0363546510379339"},{"key":"bibr10-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1016\/j.csm.2008.09.002"},{"key":"bibr11-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1016\/j.jse.2008.09.004"},{"key":"bibr12-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2012.05.887"},{"key":"bibr13-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1007\/BF01002502"},{"key":"bibr14-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1016\/j.jse.2012.02.007"},{"key":"bibr15-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0092427"},{"key":"bibr16-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2010.11.059"},{"key":"bibr17-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tea.2006.0415"},{"key":"bibr18-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-bioeng-071910-124656"},{"key":"bibr19-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2013.01.019"},{"issue":"3","key":"bibr20-0363546518764685","first-page":"71","volume":"15","author":"Morita Y","year":"2013","journal-title":"Acta Bioeng Biomech"},{"key":"bibr21-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1078\/0344-0338-00266"},{"key":"bibr22-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1016\/j.jse.2013.07.054"},{"key":"bibr23-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-013-1952-z"},{"key":"bibr24-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199710000-00031"},{"key":"bibr25-0363546518764685","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199604000-00021"},{"issue":"2","key":"bibr26-0363546518764685","first-page":"124","volume":"11","author":"Scott A","year":"2011","journal-title":"J Musculoskelet Neuronal Interact"},{"key":"bibr27-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0838.2007.00689.x"},{"key":"bibr28-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-008-0310-8"},{"key":"bibr29-0363546518764685","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.F.00512"},{"issue":"14","key":"bibr30-0363546518764685","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1242\/jcs.111.14.2067","volume":"111","author":"Takahashi I","year":"1998","journal-title":"J Cell Sci"},{"key":"bibr31-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2015.03.004"},{"key":"bibr32-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-bioeng-071811-150122"},{"key":"bibr33-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1002\/stem.1858"},{"key":"bibr34-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1053\/jars.2002.25966"},{"key":"bibr35-0363546518764685","doi-asserted-by":"publisher","DOI":"10.1016\/j.jse.2009.04.006"}],"container-title":["The American Journal of Sports Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0363546518764685","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0363546518764685","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0363546518764685","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:47:22Z","timestamp":1777369642000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0363546518764685"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,5]]},"references-count":35,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.1177\/0363546518764685"],"URL":"https:\/\/doi.org\/10.1177\/0363546518764685","relation":{},"ISSN":["0363-5465","1552-3365"],"issn-type":[{"value":"0363-5465","type":"print"},{"value":"1552-3365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,5]]}}}