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However, conflicting data have left the kinematic mechanisms leading to these injuries unclear. Quantifying the influence of sagittal and coronal plane knee kinematics on in vivo ACL strain may help to elucidate noncontact ACL injury mechanisms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose\/Hypothesis:<\/jats:title>\n                    <jats:p>The purpose of this study was to measure in vivo sagittal and coronal plane knee kinematics and ACL strain during a single-leg jump. We hypothesized that ACL strain would be modulated primarily by motion in the sagittal plane and that limited coronal plane motion would be measured during this activity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design:<\/jats:title>\n                    <jats:p>Descriptive laboratory study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Seventeen healthy participants (8 male\/9 female) underwent magnetic resonance imaging (MRI) followed by high-speed biplanar radiography, obtained as participants performed a single-leg jump. Three-dimensional models of the femur, tibia, and associated ACL attachment site footprints were created from the MRIs and registered to the radiographs to reproduce the position of the knee during the jump. ACL strain, knee flexion\/extension angles, and varus\/valgus angles were measured throughout the jump. Spearman rank correlations were used to assess relationships between mean ACL strain and kinematic variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Mean ACL strain increased with decreasing knee flexion angle (\u03c1 = \u22120.3;\n                      <jats:italic>P<\/jats:italic>\n                      = .002), and local maxima in ACL strain occurred with the knee in a straight position in both the sagittal and the coronal planes. In addition, limited coronal plane motion (varus\/valgus angle) was measured during this activity (mean \u00b1 SD, \u22120.5\u00b0\u00b1 0.3\u00b0). Furthermore, we did not detect a statistically significant relationship between ACL strain and varus\/valgus angle (\u03c1 = \u22120.01;\n                      <jats:italic>P<\/jats:italic>\n                      = .9).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>ACL strain was maximized when the knee was in a straight position in both the sagittal and coronal planes. Participants remained in &lt;1\u00b0 of varus\/valgus position on average throughout the jump. As a ligament under elevated strain is more vulnerable to injury, landing on a straight knee may be an important risk factor for ACL rupture.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Relevance:<\/jats:title>\n                    <jats:p>These data may improve understanding of risk factors for noncontact ACL injury, which may be useful in designing ACL injury prevention programs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03635465221141876","type":"journal-article","created":{"date-parts":[[2023,1,10]],"date-time":"2023-01-10T07:08:17Z","timestamp":1673334497000},"page":"422-428","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Elevated In Vivo ACL Strain Is Associated With a Straight Knee in Both the Sagittal and the Coronal Planes"],"prefix":"10.1177","volume":"51","author":[{"given":"Jacqueline N.","family":"Foody","sequence":"first","affiliation":[{"name":"Department of Biomedical Engineering, Duke University, Durham, North Carolina, USA"},{"name":"Department of Orthopaedic Surgery, Duke University, Durham, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick X.","family":"Bradley","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Duke University, Durham, North Carolina, USA"},{"name":"Department of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles E.","family":"Spritzer","sequence":"additional","affiliation":[{"name":"Department of Radiology, Duke University, Durham, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jocelyn R.","family":"Wittstein","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Duke University, Durham, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis E.","family":"DeFrate","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Duke University, Durham, North Carolina, USA"},{"name":"Department of Orthopaedic Surgery, Duke University, Durham, North Carolina, USA"},{"name":"Department of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zo\u00eb A.","family":"Englander","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Duke University, Durham, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,1,10]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546509340768"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2010.01.002"},{"issue":"2","key":"e_1_3_3_4_2","first-page":"86","article-title":"Anterior cruciate ligament injury patterns among collegiate men and women","volume":"34","author":"Arendt EA","year":"1999","unstructured":"Arendt EA, Agel J, Dick R. 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