{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T10:42:11Z","timestamp":1792579331862,"version":"4.5.0"},"reference-count":29,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T00:00:00Z","timestamp":1785456000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"national natural science foundation of china","doi-asserted-by":"publisher","award":["82302704"],"award-info":[{"award-number":["82302704"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Sports Med"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>While suprascapular nerve (SSN) entrapment is widely recognized as a complication of massive rotator cuff tears (MRCTs), its role as an independent factor affecting tendon healing remains underreported. Additionally, the therapeutic benefit of SSN release in MRCT repair remains controversial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To investigate the incidence of SSN entrapment via histological stain and whether SSN release enhances rotator cuff healing in a rat model of delayed MRCT repair.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design:<\/jats:title>\n                    <jats:p>Controlled laboratory study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A chronic MRCT model was established in rats via bilateral transection of the supraspinatus and infraspinatus tendons. After 4 weeks, 5 rats (10 shoulders) were euthanized to assess SSN entrapment incidence via immunofluorescence staining. The remaining 28 rats were randomized into 2 groups: tendon repair (TR) group (n = 14; bilateral tendon reattachment) and tendon repair + nerve release (TR+NR) group (n = 14; same repair with concurrent SSN release). Postoperative evaluations at 4 and 8 weeks included biomechanical testing (maximum load and stiffness) and histological analysis (healing quality, nerve regeneration).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      SSN entrapments were observed in 7 of 10 shoulders using Neurofilament-200 staining. The TR+NR group demonstrated significantly higher maximum load values at 8 weeks postrepair (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .05). Additionally, the TR+NR group achieved significantly superior histological scores compared to the TR group at both 4 and 8 weeks postrepair (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>SSN release significantly improved rotator cuff healing in rats with chronic MRCTs, as evidenced by enhanced biomechanical strength and histological regeneration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Relevance:<\/jats:title>\n                    <jats:p>These findings may provide some hints supporting SSN release in patients undergoing MRCT repair.<\/jats:p>\n                  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