{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T09:27:42Z","timestamp":1792661262776,"version":"4.5.0"},"reference-count":38,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[1997,9,1]],"date-time":"1997-09-01T00:00:00Z","timestamp":873072000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Sports Med"],"published-print":{"date-parts":[[1997,9]]},"abstract":"<jats:p>We conducted a randomized double-blind study of 32 subjects with acute ankle sprains to compare treatment with hyperbaric oxygen at 2 atmospheres absolute pressure (N = 16) (treatment group) with treatment with air at 1.1 atmosphere absolute pressure (N = 16) (control group) in a hyperbaric chamber. Each group received three treatments at their respective pres sures : one for 90 minutes and two for 60 minutes each. Mean age, severity grade, and time to treatment (treat ment group, 34.3 \u00b1 6.3 hours; control group, 32.6 \u00b1 4.6 hours) were similar in both groups. Joint function measured by a functional index improved from 0.40 \u00b1 0.2 to 6.3 \u00b1 0.4 with hyperbaric oxygen and from 0.8 \u00b1 0.3 to 5.3 \u00b1 0.6 with air. The change from initial to final evaluation was significantly greater in the treatment group. Foot and ankle volume by water displacement decreased from 1451 \u00b1 57 ml to 1425 \u00b1 63 ml with hyperbaric oxygen and from 1403 \u00b1 50 ml to 1371 \u00b1 45 ml with air (no difference was noted between hy perbaric oxygen treatment and air treatment using a two-way analysis of variance). Subjective pain index fell from 3.3 \u00b1 0.5 to 0.8 \u00b1 0.3 with hyperbaric oxygen and from 2.6 \u00b1 0.3 to 0.3 \u00b1 0.2 with air. No differences were noted in passive or active range of motion when comparing hyperbaric oxygen treatment with air treat ment. Time to recovery was the same in both groups (treatment, 16.0 \u00b1 6.3 days; control, 15.4 \u00b1 2.8 days). Regression analysis to determine the influence of time to treatment, initial severity of injury, hyperbaric oxy gen, and age showed no effect of hyperbaric oxygen treatment on time to recovery.<\/jats:p>","DOI":"10.1177\/036354659702500506","type":"journal-article","created":{"date-parts":[[2007,6,21]],"date-time":"2007-06-21T20:46:52Z","timestamp":1182458812000},"page":"619-625","source":"Crossref","is-referenced-by-count":45,"title":["Hyperbaric Oxygen Therapy For Acute Ankle Sprains"],"prefix":"10.1177","volume":"25","author":[{"given":"Charles N.","family":"Borromeo","sequence":"first","affiliation":[{"name":"Department of Orthopedics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey L.","family":"Ryan","sequence":"additional","affiliation":[{"name":"Department of Orthopedics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul A.","family":"Marchetto","sequence":"additional","affiliation":[{"name":"Department of Orthopedics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russell","family":"Peterson","sequence":"additional","affiliation":[{"name":"Peterson Consulting, West Chester, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfred A.","family":"Bove","sequence":"additional","affiliation":[{"name":"Section of Cardiology, Temple University Medical School, Philadelphia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1997,9,1]]},"reference":[{"key":"atypb1","unstructured":"Boerema I., Meyne NG, Brummelkamp WK, et al Life without blood. 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