{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T04:55:37Z","timestamp":1777784137465,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2003,2,1]],"date-time":"2003-02-01T00:00:00Z","timestamp":1044057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Artif Organs"],"published-print":{"date-parts":[[2003,2]]},"abstract":"<jats:p>The aim of this study was to verify if the degree of pre-HD acidosis and its correction post-HD is related to body fluid expansion during the interdialytic period.<\/jats:p>\n                  <jats:p>Twelve uremic patients without major problems, with stable hematocrit, with regular and similar HD-session characteristics, but widely varying amounts of body fluid expansion in the interdialytic period were included.<\/jats:p>\n                  <jats:p>\n                    Blood samples were collected from arterial line pre-and post-HD, anaerobically in heparinized syringes, for determination of HCO\n                    <jats:sub>3<\/jats:sub>\n                    <jats:sup>-<\/jats:sup>\n                    , pH and PaCO\n                    <jats:sub>2<\/jats:sub>\n                    (radiometer Copenhagen ABL 300 Acid-Base Laboratory), in two similar HD-sessions for each patient (12 patients, 24 HD-sessions). The percentage (%) of body weight gain in the interdialytic period was also estimated. For each patient, the mean value of parameters studied in the two HD-sessions was used for the evaluation of findings. According to mean values (\u00b1SD) of HCO\n                    <jats:sub>3<\/jats:sub>\n                    <jats:sup>-<\/jats:sup>\n                    , pH and PaCO\n                    <jats:sub>2<\/jats:sub>\n                    Pre-HD (18.26\u00b11.99 mmol\/L, 7.31\u00b10.03, 36.27\u00b12.5 mmHg respectively) and post-HD (26.37\u00b11.7, 7.43\u00b10.03, 38.43\u00b12.10 respectively) patients are acidotic pre-HD and slightly alkalemic post-HD. Correlation between the percentage (%) of interdialytic body weight gain (IBWG) and the values of HCO\n                    <jats:sub>3<\/jats:sub>\n                    <jats:sup>-<\/jats:sup>\n                    , pH and PaCO\n                    <jats:sub>2<\/jats:sub>\n                    , Pre-HD (r=-0.814, p &lt;0.001; r=-0.931, p &lt;0.001; r=0,100 NS; respectively) and post-HD (r=-0.958, p &lt;0.001; r=-0.937, p &lt;0.001; r=-0.504 NS; respectively) indicates a significant and negative relationship of IBWG% with HCO\n                    <jats:sub>3<\/jats:sub>\n                    <jats:sup>-<\/jats:sup>\n                    and pH pre- and post-HD, but not with PCO\n                    <jats:sub>2<\/jats:sub>\n                    .\n                  <\/jats:p>\n                  <jats:p>\n                    In conclusion, the negative relationship of IBWG% with HCO\n                    <jats:sub>3<\/jats:sub>\n                    <jats:sup>-<\/jats:sup>\n                    and pH pre- and post-HD indicates that the body fluid expansion during the interdialytic period contributes to a dilutional acidosis pre-HD, but not to a contraction alkalosis post-HD, by the elimination of fluid during the HD-session.\n                  <\/jats:p>","DOI":"10.1177\/039139880302600207","type":"journal-article","created":{"date-parts":[[2018,1,19]],"date-time":"2018-01-19T01:22:28Z","timestamp":1516324948000},"page":"135-138","source":"Crossref","is-referenced-by-count":0,"title":["Pre-HD Dilution Acidosis, without Post-HD Contraction Alkalosis in Uremic Patients"],"prefix":"10.1177","volume":"26","author":[{"given":"B.","family":"Agroyannis","sequence":"first","affiliation":[{"name":"Department of Nephrology, Aretaieion University Hospital, Athens - Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Fourtounas","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Aretaieion University Hospital, Athens - Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Tzanatos","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Aretaieion University Hospital, Athens - Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Kapetanaki","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Aretaieion University Hospital, Athens - Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Dalamangas","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Aretaieion University Hospital, Athens - Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.V.","family":"Vlahakos","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Aretaieion University Hospital, Athens - Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2003,2,1]]},"reference":[{"key":"bibr1-039139880302600207","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1975.114"},{"key":"bibr2-039139880302600207","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1594.1982.tb04133.x"},{"issue":"41","key":"bibr3-039139880302600207","first-page":"S179","volume":"43","author":"Zuccelli P.","year":"1993","journal-title":"Kidney Int"},{"key":"bibr4-039139880302600207","doi-asserted-by":"publisher","DOI":"10.1042\/cs1010329"},{"key":"bibr5-039139880302600207","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199702000-00028"},{"key":"bibr6-039139880302600207","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199710000-00054"},{"key":"bibr7-039139880302600207","first-page":"M372","volume":"37","author":"Rault R.","year":"1991","journal-title":"ASAIO Trans"},{"key":"bibr8-039139880302600207","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V3111804"}],"container-title":["The International Journal of Artificial Organs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/039139880302600207","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/039139880302600207","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:39:39Z","timestamp":1777491579000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/039139880302600207"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,2]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2003,2]]}},"alternative-id":["10.1177\/039139880302600207"],"URL":"https:\/\/doi.org\/10.1177\/039139880302600207","relation":{},"ISSN":["0391-3988","1724-6040"],"issn-type":[{"value":"0391-3988","type":"print"},{"value":"1724-6040","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,2]]}}}