{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T04:55:03Z","timestamp":1777784103623,"version":"3.51.4"},"reference-count":30,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2003,10,1]],"date-time":"2003-10-01T00:00:00Z","timestamp":1064966400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Artif Organs"],"published-print":{"date-parts":[[2003,10]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To study the effect of MARS on serum electrolytes during liver failure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Twenty-three patients admitted to a quaternary health care facility from September 2000 to May 2002, 22 adults and 1 child, 11 males (48%) and 12 females (52%), age 15\u201370 (median 53), treated with MARS for: 12 acute-on-chronic liver failure (52%); 4 fulminant hepatic failure (17%); 3 intractable pruritus (13%); 2 primary-non-function (9%); 2 following major liver resection (9%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Procedures<\/jats:title>\n                    <jats:p>Sodium, potassium, chloride, phosphorus, calcium, and magnesium were measured in the serum, ultrafiltrate and albumin circuit before and after MARS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Statistical methods<\/jats:title>\n                    <jats:p>A comparison of electrolyte concentrations, before and after MARS, was performed using a paired t test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main findings<\/jats:title>\n                    <jats:p>Serum electrolyte concentrations before and after MARS, while statistically significant in some cases, were very small, and of no clinical relevance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>MARS exchanges potassium, chloride, calcium, and magnesium by ultrafiltration; sodium by the albumin dialysis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/039139880302601008","type":"journal-article","created":{"date-parts":[[2018,1,19]],"date-time":"2018-01-19T01:20:51Z","timestamp":1516324851000},"page":"918-923","source":"Crossref","is-referenced-by-count":5,"title":["Changes in Serum Electrolytes during Treatment of Patients in Liver Failure with Molecular Adsorbent Recirculating System"],"prefix":"10.1177","volume":"26","author":[{"given":"C.","family":"Doria","sequence":"first","affiliation":[{"name":"Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, Pennsylvania - USA"},{"name":"Department of Surgery, Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione IsMeTT, UPMC Italy, Palermo - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.R.","family":"Doyle","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care Medicine, Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione IsMeTT - UPMC Italy, Palermo - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Mandal\u00e0","sequence":"additional","affiliation":[{"name":"Department of Surgery, Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione IsMeTT, UPMC Italy, Palermo - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.R.","family":"Marino","sequence":"additional","affiliation":[{"name":"Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, Pennsylvania - USA"},{"name":"Department of Surgery, Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione IsMeTT, UPMC Italy, Palermo - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Caruana","sequence":"additional","affiliation":[{"name":"Department of Surgery, Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione IsMeTT, UPMC Italy, Palermo - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Gruttadauria","sequence":"additional","affiliation":[{"name":"Department of Surgery, Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione IsMeTT, UPMC Italy, Palermo - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Lauro","sequence":"additional","affiliation":[{"name":"Department of Surgery, Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione IsMeTT, UPMC Italy, Palermo - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Magnone","sequence":"additional","affiliation":[{"name":"Department of Surgery, Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione IsMeTT, UPMC Italy, Palermo - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. 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