{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T04:58:52Z","timestamp":1777784332881,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2004,8,1]],"date-time":"2004-08-01T00:00:00Z","timestamp":1091318400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Artif Organs"],"published-print":{"date-parts":[[2004,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Evaluation of the respiratory pattern selected by the Adaptive Support Ventilation (ASV) in ventilated patients with acute, chronic respiratory failure and normal lungs and in a physical lung model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>We tested ASV both on patients and in a physical lung model, with a normal level of minute ventilation and with minute ventilation increased by 30%. In each patient, respiratory pattern, mechanics and blood gases were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>General ICU of a University Hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In patients with normal lungs, mean values\u00b1SD were: tidal volume (Vt) 558.1\u00b1142.4mL, respiratory rate (RR) 12.6\u00b11.3b\/min and inspiratory time\/total time ratio (Ti\/Ttot) 42.4\u00b14.1%; in COPD, mean values\u00b1SD were: Vt 724\u00b1171mL, RR 9.2\u00b12.7b\/min and Ti\/Ttot 26.6\u00b110.5%; in restrictive ones, mean values\u00b1SD were: Vt 550.2\u00b177.0mL, RR 15.8\u00b12.6b\/min, Ti\/Ttot 47.5\u00b12.5%. In the lung model, at a normal setting, mean values\u00b1SD were: Vt 523\u00b118.5mL, RR 14\u00b10.0b\/min, Ti\/Ttot 44.0%, in COPD, mean values\u00b1SD were: Vt 678\u00b10.0mL, RR 9\u00b10.0b\/min, Ti\/Ttot 20\u00b10.7%, in restrictive one, mean values\u00b1SD were: Vt 513\u00b112.8mL, RR 15\u00b10.0b\/min, Ti\/Ttot 48\u00b11.5%. In model hyperventilation conditions in a normal setting a Vt of 582\u00b116.6mL, RR 16\u00b10.0b\/min, Ti\/Ttot 48\u00b10.0% were selected, in the obstructive setting Vt 883\u00b10.0mL, RR 9\u00b10.0b\/min, Ti\/Ttot 20\u00b10.0% and in a restrictive one Vt 545\u00b18.4mL, RR 18\u00b10.0b\/min, Ti\/Ttot 50\u00b10.0%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In normal patients ASV selected a ventilatory pattern close to the physiological one, in COPD almost a high expiratory time pattern and in restrictive ones a reduced tidal volume pattern. In the model the selection was similar. In the hyperventilation test, ASV chose a balanced increase in both Vt and RR.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/039139880402700809","type":"journal-article","created":{"date-parts":[[2018,1,12]],"date-time":"2018-01-12T01:53:04Z","timestamp":1515721984000},"page":"709-716","source":"Crossref","is-referenced-by-count":20,"title":["Evaluation of Adaptive Support Ventilation in Paralysed Patients and in a Physical Lung Model"],"prefix":"10.1177","volume":"27","author":[{"given":"M.","family":"Belliato","sequence":"first","affiliation":[{"name":"Ist Anesthesia and Reanimation Service, IRCCS Policlinico San Matteo di Pavia, Pavia - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Palo","sequence":"additional","affiliation":[{"name":"Ist Anesthesia and Reanimation Service, IRCCS Policlinico San Matteo di Pavia, Pavia - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Pasero","sequence":"additional","affiliation":[{"name":"3rd Anesthesia and Reanimation, San Giovanni Battista Maggiore Hospital, Molinette, Torino - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.A.","family":"Iotti","sequence":"additional","affiliation":[{"name":"Anesthesia and Reanimation, SS. Antonio e Biagio e C. Arrigo Hospital, Alessandria - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Mojoli","sequence":"additional","affiliation":[{"name":"Ist Anesthesia and Reanimation Service, IRCCS Policlinico San Matteo di Pavia, Pavia - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Braschi","sequence":"additional","affiliation":[{"name":"Ist Anesthesia and Reanimation Service, IRCCS Policlinico San Matteo di Pavia, Pavia - Italy"},{"name":"Chair of Anesthesia and Reanimation, University of Pavia, Pavia - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2004,8,1]]},"reference":[{"key":"bibr1-039139880402700809","doi-asserted-by":"publisher","DOI":"10.1016\/S1078-5337(05)70040-X"},{"key":"bibr2-039139880402700809","first-page":"255","volume":"46","author":"Branson R.D.","year":"2001","journal-title":"Respir Care"},{"key":"bibr3-039139880402700809","doi-asserted-by":"publisher","DOI":"10.1016\/S1078-5337(05)70041-1"},{"key":"bibr4-039139880402700809","doi-asserted-by":"publisher","DOI":"10.1007\/s001340051001"},{"key":"bibr5-039139880402700809","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12329-X"},{"key":"bibr6-039139880402700809","doi-asserted-by":"publisher","DOI":"10.1016\/S1078-5337(05)70049-6"},{"key":"bibr7-039139880402700809","first-page":"A123","volume":"124","author":"Olivei M.","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"key":"bibr8-039139880402700809","doi-asserted-by":"publisher","DOI":"10.1016\/S1078-5337(05)70044-7"},{"key":"bibr9-039139880402700809","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/136.1.225"},{"key":"bibr10-039139880402700809","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.149.3.7509706"},{"key":"bibr11-039139880402700809","doi-asserted-by":"publisher","DOI":"10.1016\/0010-4809(74)90027-5"},{"key":"bibr12-039139880402700809","doi-asserted-by":"publisher","DOI":"10.1007\/BF01707409"},{"key":"bibr13-039139880402700809","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200005043421801"},{"key":"bibr14-039139880402700809","first-page":"991","volume":"126","author":"Kimball Wr","year":"1982","journal-title":"Am Rev Respir Dis"},{"key":"bibr15-039139880402700809","first-page":"592","volume":"2","author":"Otis A.B.","year":"1950","journal-title":"J Appl Phys"},{"key":"bibr16-039139880402700809","doi-asserted-by":"publisher","DOI":"10.1007\/s001340000632"},{"key":"bibr17-039139880402700809","first-page":"A3","volume":"159","author":"Galbusera C.","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"key":"bibr18-039139880402700809","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1963.18.3.519"},{"key":"bibr19-039139880402700809","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1979.47.2.319"},{"key":"bibr20-039139880402700809","doi-asserted-by":"publisher","DOI":"10.1109\/10.277271"}],"container-title":["The International Journal of Artificial Organs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/039139880402700809","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/039139880402700809","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:40:29Z","timestamp":1777491629000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/039139880402700809"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,8]]},"references-count":20,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2004,8]]}},"alternative-id":["10.1177\/039139880402700809"],"URL":"https:\/\/doi.org\/10.1177\/039139880402700809","relation":{},"ISSN":["0391-3988","1724-6040"],"issn-type":[{"value":"0391-3988","type":"print"},{"value":"1724-6040","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,8]]}}}