{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T04:57:26Z","timestamp":1777784246854,"version":"3.51.4"},"reference-count":33,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2004,11,1]],"date-time":"2004-11-01T00:00:00Z","timestamp":1099267200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Artif Organs"],"published-print":{"date-parts":[[2004,11]]},"abstract":"<jats:p>Fulminant hepatic failure (FHF) carries a high mortality. We aimed to review the prognostic factors and explore the potential role of Liver Dialysis (LD).<\/jats:p>\n                  <jats:p>Fifty-two patients were reviewed. The etiologies were acetaminophen toxicity (33%), viral hepatitis (18%), autoimmune (10%), idiosyncratic drug reactions (8%), others (6%) and undetermined (25%). Patients with acetaminophen had a significantly higher survival compared to the non-acetaminophen group (p=0.04). Patients with grade 3 encephalopathy had a mortality of 68%, among 5 patients with grade IV encephalopathy, 2 survived and both had had treatment with LD.<\/jats:p>\n                  <jats:p>Chi-square with Fisher's exact test was used for statistical analysis.<\/jats:p>\n                  <jats:p>Our study confirmed that the diagnosis of non-acetaminophen induced FHF and reduced initial serum factor V level are associated with fatal outcome. Timely OLT significantly improved the survival. The role of LD in hepatic regeneration or as a bridge to OLT needs to be further studied with prospective control trials.<\/jats:p>","DOI":"10.1177\/039139880402701108","type":"journal-article","created":{"date-parts":[[2018,1,19]],"date-time":"2018-01-19T01:22:13Z","timestamp":1516324933000},"page":"956-961","source":"Crossref","is-referenced-by-count":3,"title":["Fulminant Hepatic Failure and the Potential Role of Liver Dialysis"],"prefix":"10.1177","volume":"27","author":[{"given":"M.","family":"Akdogan","sequence":"first","affiliation":[{"name":"Division of Liver Transplantation, Integris Baptist Medical Center, Oklahoma City, OK - USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Aladag","sequence":"additional","affiliation":[{"name":"Division of Liver Transplantation, Integris Baptist Medical Center, Oklahoma City, OK - 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