{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T16:28:02Z","timestamp":1790958482848,"version":"4.1.0"},"reference-count":39,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T00:00:00Z","timestamp":1101859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Artif Organs"],"published-print":{"date-parts":[[2004,12]]},"abstract":"<jats:p>Cardiovascular events are the main cause of death in hemodialysis patients. Nevertheless, acute myocardial infarction may be misdiagnosed in uremic patients, because typical markers have a high rate of false positivity. A recent two-year prospective study showed that predialytic high serum concentrations of troponin T and CK-MB mass were associated with high mortality, cardiac mortality, myocardial infarction and unstable angina (MACEs). We studied 16 uremic patients (13 M; 3 W) on standard HD and 6 patients (4 M; 2 W) on on-line HDF, who had been taking folic acid for at least three months. Patients who suffered from acute or chronic cardiac ischemic disease were excluded. Anthropometric parameters, pre and post-dialytic pH, HCO3 and electrolytes did not differ between the two groups. Kt\/V and URR % were lower in conventional HD vs on-line HDF (p&lt;0.04; p&lt;0.04). ORR % was strongly elevated in on-line HDF compared with HD (p&lt;0.005). In conventional HD, ORR % was directly correlated with Kt\/V and URR% (r = 0.49, p&lt;0.04; r = 0.48, p&lt;0.04, respectively). Even in on-line HDF ORR % was directly correlated with Kt\/V and URR % (r = 0.79, p&lt;0.04; r = 0.76, p&lt;0.05, respectively). Troponin I and CK-MB mass were not significantly different in pre vs post-dialysis, both in standard HD and on-line HDF. Nevertheless, in standard HD postdialytic troponin I correlated with serum sodium concentration (r = 0.93, p &lt; 0.000), potassium (r = 0.67, p &lt; 0.004) and serum chlorine (r = 0.92, p &lt; 0.92, p &lt; 0.000). CK-MB mass showed a correlation with serum chlorine (r = 0.49, p &lt; 0.05). Postdialytic CK-MB mass correlated with serum potassium in on-line HDF (r = 0.83, p &lt; 0.03). Our data suggest that hemodialytic treatments, both standard HD and on-line HDF, do not modify serum troponin I and CK-MB mass. Consequently, we can use these parameters for the diagnostic approach in acute or chronic ischemic heart disease in hemodialysis patients.<\/jats:p>","DOI":"10.1177\/039139880402701212","type":"journal-article","created":{"date-parts":[[2018,1,19]],"date-time":"2018-01-19T01:20:33Z","timestamp":1516324833000},"page":"1083-1090","source":"Crossref","is-referenced-by-count":8,"title":["Cardiovascular Risk Markers in Hemodialysis Patients"],"prefix":"10.1177","volume":"27","author":[{"given":"S.","family":"Urso","sequence":"first","affiliation":[{"name":"Unit\u00e0 Operativa di Nefrologia e Dialisi, Ospedale S. Marta e S. Venera, Acireale (CT) - Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Garozzo","sequence":"additional","affiliation":[{"name":"Unit\u00e0 Operativa di Nefrologia e Dialisi, Ospedale S. Marta e S. 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