{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:07:24Z","timestamp":1787018844550,"version":"build-2736575974"},"reference-count":20,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2018,12,6]],"date-time":"2018-12-06T00:00:00Z","timestamp":1544054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Artif Organs"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:p>\n                    Following implantation of a left ventricular assist device, the build-up and long-term maintenance of adequate exercise capacity and functional performance become crucial. The aim of this study was to observe the development of exercise-related values at different times, as well as to detect possible influencing factors. We performed a prospective single-centre study: 10 patients (63\u2009years, 100% male, body mass index\u2009=\u200927.5, 100% HeartWare) underwent the following diagnostic tests during cardiac rehabilitation and during two subsequent ambulatory visits: 6-min walking test, handgrip strength test, cardiopulmonary exercise test and Minnesota Living with Heart Failure questionnaire. Mean follow-up was 482\u2009days after left ventricular assist device implantation. Significant improvements could be observed between the end of cardiac rehabilitation and ambulatory visit 1; 6-min walking distance increased from 367 to 449\u2009m (p\u2009&lt;\u20090.01), peak VO\n                    <jats:sub>2<\/jats:sub>\n                    from 10.0 to 11.9\u2009mL\/kg\/min (p\u2009&lt;\u20090.05) and peak load from 62.4 to 83.0\u2009W (p\u2009&lt;\u20090.01). However, there were no further improvements between ambulatory visit 1 and ambulatory visit 2. In the long term, a significant mean weight gain of more than 10\u2009kg could be observed (p\u2009&lt;\u20090.01). A negative linear correlation between weight gain and absolute improvement in peak load (r\u2009=\u2009\u22120.77, p\u2009&lt;\u20090.01) and peak VO\n                    <jats:sub>2<\/jats:sub>\n                    (r\u2009=\u2009\u22120.75, p\u2009&lt;\u20090.05) could be demonstrated. In conclusion, exercise-related values following left ventricular assist device implantation initially improve significantly. Later, however, no further improvements can be observed. In the long term, pronounced weight gain is conspicuous, concomitant with a significantly lower increase in exercise values of the patients. In the future, both dietary and structured physical activity follow-up interventions should be integrated in patient routines.\n                  <\/jats:p>","DOI":"10.1177\/0391398818815492","type":"journal-article","created":{"date-parts":[[2018,12,6]],"date-time":"2018-12-06T06:49:04Z","timestamp":1544078944000},"page":"201-206","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Development of exercise-related values in heart failure patients supported with a left ventricular assist device"],"prefix":"10.1177","volume":"42","author":[{"given":"Thomas","family":"Schmidt","sequence":"first","affiliation":[{"name":"Sch\u00fcchtermann-Klinik Bad Rothenfelde, Bad Rothenfelde, Germany"},{"name":"Institute of Cardiology and Sports Medicine, German Sport University Cologne, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birna","family":"Bjarnason-Wehrens","sequence":"additional","affiliation":[{"name":"Institute of Cardiology and Sports Medicine, German Sport University Cologne, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Mommertz","sequence":"additional","affiliation":[{"name":"Sch\u00fcchtermann-Klinik Bad Rothenfelde, Bad Rothenfelde, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Schulte-Eistrup","sequence":"additional","affiliation":[{"name":"Sch\u00fcchtermann-Klinik Bad Rothenfelde, Bad Rothenfelde, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Detlev","family":"Willemsen","sequence":"additional","affiliation":[{"name":"Sch\u00fcchtermann-Klinik Bad Rothenfelde, Bad Rothenfelde, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Sindermann","sequence":"additional","affiliation":[{"name":"Sch\u00fcchtermann-Klinik Bad Rothenfelde, Bad Rothenfelde, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-Georg","family":"Predel","sequence":"additional","affiliation":[{"name":"Institute of Cardiology and Sports Medicine, German Sport University Cologne, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils","family":"Reiss","sequence":"additional","affiliation":[{"name":"Sch\u00fcchtermann-Klinik Bad Rothenfelde, Bad Rothenfelde, 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