{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T22:04:09Z","timestamp":1788559449860,"version":"build-2803163510"},"reference-count":32,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2019,3,6]],"date-time":"2019-03-06T00:00:00Z","timestamp":1551830400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Fundo de Incentivo \u00e0 Pesquisa e Eventos - Hospital de Clinicas de Porto Alegre"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Artif Organs"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:p>\n                    Some biomaterial scaffolds can positively interfere with tissue regeneration and are being developed to successfully repair the tissue function. The possibility of using epithelial cells combined with biomaterials appears to be a new option as therapeutic application. This combination emerges as a possibility for patients with Mayer\u2013Rokitansky\u2013Kuster\u2013Hauser syndrome which requires vaginal repair and can be performed with tissue-engineered solution containing cells and biomaterials. It is expected that tissue-engineered solution containing cells and biomaterials would promote tissue repair in a more efficient, modern, and safe way. This study tested the efficiency of tissue-engineered solution containing human malignant melanoma cell line (HMV-II) and different biomaterials, including Cellprene\n                    <jats:sup>\u00ae<\/jats:sup>\n                    , Membracel\n                    <jats:sup>\u00ae<\/jats:sup>\n                    , and poly lactic-co-glycolic acid\/epoxidized polyisoprene. The cells adhered better on poly lactic-co-glycolic acid\/epoxidized polyisoprene, and it was found that tissue-engineered solution may also contain mesenchymal stem cells cultivated on poly lactic-co-glycolic acid\/epoxidized polyisoprene. Histological, immunofluorescence, and scanning electron microscopy analyses were performed. These initial in vitro results suggest that tissue-engineered solution containing cells and poly lactic-co-glycolic acid\/epoxidized polyisoprene is a potential for tissue reconstruction.\n                  <\/jats:p>","DOI":"10.1177\/0391398819833383","type":"journal-article","created":{"date-parts":[[2019,3,6]],"date-time":"2019-03-06T06:02:12Z","timestamp":1551852132000},"page":"307-314","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Tissue-engineered solution containing cells and biomaterials\u2014an in vitro study: A perspective as a novel therapeutic application"],"prefix":"10.1177","volume":"42","author":[{"given":"Nicole Andr\u00e9a Corbellini","family":"Henckes","sequence":"first","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias da Sa\u00fade\u2014Ginecologia e Obstetr\u00edcia, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, 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