{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T05:08:54Z","timestamp":1777784934530,"version":"3.51.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,11,20]],"date-time":"2020-11-20T00:00:00Z","timestamp":1605830400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Artif Organs"],"published-print":{"date-parts":[[2021,6]]},"abstract":"\n Introduction:<\/jats:title>\n \n Axial-flow and centrifugal-flow left ventricular assist devices (LVAD) have been utilized in the management of heart failure, but it remains unknown whether these devices differ in end-organ perfusion. Our goal was to evaluate the association between device type and regional cerebral oxygen saturation (rSO\n 2<\/jats:sub>\n ), and determine if this confers any benefit in short-term postoperative outcomes.\n <\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n Adult patients who underwent primary LVAD implantation at our institution from 2014 to 2019 were retrospectively analyzed. Patients were stratified into axial-flow and centrifugal-flow groups. Intraoperative rSO\n 2<\/jats:sub>\n readings were used to calculate the change in mean rSO\n 2<\/jats:sub>\n from pre- to post-bypass. Multivariable modeling was performed to compare delta rSO\n 2<\/jats:sub>\n between groups, and to analyze the association between LVAD type and postoperative outcomes.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n There were 152 patients included, of which 76 had an axial-flow device and 76 had a centrifugal-flow device implanted. The rSO\n 2<\/jats:sub>\n level increased from pre-bypass to post-bypass on average 3.5% (CI: 2.1 to 5.0) for the axial group compared to 0.1% (CI: \u22121.2 to 1.4) for the centrifugal group, which was a significant difference (\u03b2\u2009=\u2009\u22122.22, CI: \u22124.21 to \u22120.32, p\u2009=\u20090.022). Axial devices approached significance for lower odds of postoperative complications (OR: 0.35, CI: 0.11 to 1.06, p\u2009=\u20090.063), and were associated with significantly shorter ICU LOS (\u03b2\u2009=\u2009\u22120.36, CI: \u22120.60 to \u22120.11, p\u2009=\u20090.004).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n \n Axial devices resulted in a greater increase in rSO\n 2<\/jats:sub>\n than centrifugal pumps after separation from CPB. Further investigation is warranted to evaluate the effect of LVAD selection on long-term end-organ perfusion and subsequent patient outcomes.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/0391398820973679","type":"journal-article","created":{"date-parts":[[2020,11,20]],"date-time":"2020-11-20T03:57:08Z","timestamp":1605844628000},"page":"404-410","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Finding a proper \u201cMate\u201d: Comparison of left ventricular assist devices using cerebral oximetry"],"prefix":"10.1177","volume":"44","author":[{"given":"Morgan L","family":"Montgomery","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Perioperative and Pain Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5464-0423","authenticated-orcid":false,"given":"Blaine","family":"Stannard","sequence":"additional","affiliation":[{"name":"Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siarhei","family":"Dzedzik","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Perioperative and Pain Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hung-Mo","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anelechi","family":"Anyanwu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew A","family":"Levin","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Perioperative and Pain Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muoi","family":"Trinh","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Perioperative and Pain Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,11,20]]},"reference":[{"key":"bibr1-0391398820973679","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.779"},{"key":"bibr2-0391398820973679","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcm.2019.05.013"},{"key":"bibr3-0391398820973679","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivz202"},{"key":"bibr4-0391398820973679","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2019.12.005"},{"key":"bibr5-0391398820973679","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.118.037231"},{"key":"bibr6-0391398820973679","doi-asserted-by":"publisher","DOI":"10.1532\/HSF98.20041062"},{"key":"bibr7-0391398820973679","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000246814.29362.f4"},{"key":"bibr8-0391398820973679","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1900486"},{"key":"bibr9-0391398820973679","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2017.08.029"}],"container-title":["The International Journal of Artificial Organs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0391398820973679","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0391398820973679","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0391398820973679","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:42:21Z","timestamp":1777491741000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0391398820973679"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,20]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1177\/0391398820973679"],"URL":"https:\/\/doi.org\/10.1177\/0391398820973679","relation":{},"ISSN":["0391-3988","1724-6040"],"issn-type":[{"value":"0391-3988","type":"print"},{"value":"1724-6040","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,20]]}}}