{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:01:50Z","timestamp":1790208110670,"version":"4.1.0"},"reference-count":15,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2022,12,10]],"date-time":"2022-12-10T00:00:00Z","timestamp":1670630400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Artif Organs"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Assessment of the results of the ProtekDuo cannula applied for dedicated right ventricular support with oxygenator in ARDS secondary to COVID-19.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Systematic literature search in NHS library, Medline (Pubmed) and EMBASE using appropriate keywords as well as PICOS and PRISMA approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Out of 285 publications found, 5 publications met the search criteria and were included in this review. A total of 194 patients with ARDS secondary to COVID-19 underwent ProtekDuo placement to establish a combination of respiratory [veno-venous extracorporeal membrane oxygenation (V-V ECMO)] and right ventricular support. Patients treated using the ProtekDuo cannula had survival rates between 59% and 89% throughout the five studies, and a significant survival benefit when compared to an invasive ventilation group or compared to dual site V-V ECMO or other double lumen ECMO cannulas. One study focused on extubation and discontinuation of ventilator support, which could be achieved in 100% of ProtekDuo patients. An association for reduced incidence of acute kidney injury (AKI) and use of continuous renal replacement therapy (CRRT) could be shown when the ProtekDuo was used.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Only limited literature is available for the ProtekDuo in V-P ECMO configuration in the setting of COVID-19 ARDS and should be interpreted with caution. Data on the ProtekDuo is suggestive for lower rates of mortality, AKI and CRRT as compared to other respiratory support modalities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03913988221142904","type":"journal-article","created":{"date-parts":[[2022,12,10]],"date-time":"2022-12-10T04:29:07Z","timestamp":1670646547000},"page":"93-98","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":32,"title":["The ProtekDuo in ECMO configuration for ARDS secondary to COVID-19: A systematic review"],"prefix":"10.1177","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2406-655X","authenticated-orcid":false,"given":"Marc O","family":"Maybauer","sequence":"first","affiliation":[{"name":"Nazih Zuhdi Transplant Institute, Advanced Cardiac and Specialty Critical Care, Oklahoma City, OK, USA"},{"name":"Department of Anaesthesiology and Intensive Care Medicine, Philipps University, Marburg, Germany"},{"name":"Critical Care Research Group, Prince Charles Hospital, University of Queensland, Brisbane, QLD, Australia"},{"name":"Department of Anesthesiology, Division of Critical Care Medicine, University of Florida College of Medicine, Gainesville, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Capoccia","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk M","family":"Maybauer","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine, Philipps University, Marburg, Germany"},{"name":"Critical Care Research Group, Prince Charles Hospital, University of Queensland, Brisbane, QLD, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Lorusso","sequence":"additional","affiliation":[{"name":"ECLS Centrum, Cardio -Thoracic Surgery Department, Heart & Vascular Center, Maastricht University Medical Center, Maastricht (MUMC), The Netherlands; and Cardiovascular Research Institute (CARIM), Maastricht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justyna","family":"Swol","sequence":"additional","affiliation":[{"name":"Department of Pneumology, Allergology and Sleep Medicine, Paracelsus Medical University, Nuremberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph M","family":"Brewer","sequence":"additional","affiliation":[{"name":"Nazih Zuhdi Transplant Institute, Advanced Cardiac and Specialty Critical Care, Oklahoma City, OK, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,12,10]]},"reference":[{"key":"bibr1-03913988221142904","doi-asserted-by":"publisher","DOI":"10.1177\/02676591221090607"},{"key":"bibr2-03913988221142904","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-019-2334-8"},{"key":"bibr3-03913988221142904","doi-asserted-by":"publisher","DOI":"10.1177\/0885066621993739"},{"key":"bibr4-03913988221142904","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000097"},{"key":"bibr5-03913988221142904","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0000000000000227"},{"key":"bibr6-03913988221142904","doi-asserted-by":"publisher","DOI":"10.4103\/aca.aca_49_21"},{"issue":"9","key":"bibr7-03913988221142904","first-page":"623","volume":"44","author":"Maybauer MO","year":"2021","journal-title":"Int J Artif Organs"},{"key":"bibr8-03913988221142904","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2020.3950"},{"key":"bibr9-03913988221142904","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2021.03.017"},{"key":"bibr10-03913988221142904","doi-asserted-by":"publisher","DOI":"10.1111\/aor.14213"},{"key":"bibr11-03913988221142904","doi-asserted-by":"publisher","DOI":"10.1111\/aor.14381"},{"key":"bibr12-03913988221142904","doi-asserted-by":"publisher","DOI":"10.1177\/03913988221121355"},{"key":"bibr13-03913988221142904","doi-asserted-by":"publisher","DOI":"10.1111\/aor.14370"},{"key":"bibr14-03913988221142904","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2021.0284"},{"key":"bibr15-03913988221142904","first-page":"790","volume":"74","author":"Page MJ","year":"2021","journal-title":"BMJ"}],"container-title":["The International Journal of Artificial Organs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03913988221142904","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03913988221142904","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03913988221142904","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:40:43Z","timestamp":1777491643000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03913988221142904"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,10]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.1177\/03913988221142904"],"URL":"https:\/\/doi.org\/10.1177\/03913988221142904","relation":{},"ISSN":["0391-3988","1724-6040"],"issn-type":[{"value":"0391-3988","type":"print"},{"value":"1724-6040","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,10]]}}}