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In this setting, treatment is mainly supportive as there is no consensus on antiviral therapy based on non-nucleoside reverse transcriptase inhibitors. Single-pass albumin dialysis is a liver-support technique for patients suffering from liver failure, that has shown effectiveness in the removal of both water-soluble and albumin-bound toxins, which accumulate due to impairment of the liver\u2019s cleansing function. We report here the case of a 62-year-old male who presented with a severe acute hepatitis B infection, liver failure, and marked hyperbilirubinemia. Treatment with single-pass albumin dialysis combined with a hemoperfusion device was successful in improving clinical, physiological, and laboratory parameters.<\/jats:p>","DOI":"10.1177\/03913988221143142","type":"journal-article","created":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T01:03:06Z","timestamp":1670547786000},"page":"81-84","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Efficacy of hemoperfusion with Seraph-100 in series with single pass albumin dialysis in acute hepatitis B infection: A case report"],"prefix":"10.1177","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0608-7608","authenticated-orcid":false,"given":"Luca","family":"Piscitani","sequence":"first","affiliation":[{"name":"Nephrology and Dialysis Unit, Department of Medicine, S. 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