{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T05:01:16Z","timestamp":1777784476252,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T00:00:00Z","timestamp":1698710400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Artif Organs"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:p>Severe left ventricular failure can progress to right ventricular failure, necessitating alternatives to heart transplantation, such as total artificial heart (TAH) treatment. Conventional TAHs encounter challenges associated with miniaturization and hemocompatibility owing to their reliance on mechanical valves and bearings. A magnetically levitated TAH (IB-Heart) was developed, utilizing a magnetic bearing. The IB-Heart features a distinctive biventricular shunt channel situated between the flow paths of the left and right centrifugal blood pumps, simplifying and miniaturizing its control system. However, the impact of these shunt channels remains underexplored. This study aimed to investigate the effects of shunt flow on pump characteristics and assess the IB-Heart\u2019s potential to regulate flow balance between systemic and pulmonary circulation. At a rotational speed of 2000\u2009rpm and flow rate range of 0\u201310\u2009L\/min, shunt flow exhibited a minor impact, with a 1.4\u2009mmHg (1.3%) effect on pump characteristics. Shunt flow variation of about 0.13\u2009L\/min correlated with a 10\u2009mmHg pressure difference between the pumps\u2019 afterload and preload conditions. This variance was linked to changes in the inlet flow rates of the left and right pumps, signifying the ventricular shunt structure\u2019s capacity to mirror the function of an atrial shunt in alleviating pulmonary congestion. The IB-Heart\u2019s ventricular shunt structure enables passive regulation of left-right flow balance. The findings establish a fundamental technical groundwork for the development of IB-Hearts and TAHs with similar shunt structures. The innovative coupling of centrifugal pumps and the resultant effects on flow dynamics contribute to the advancement of TAH technology.<\/jats:p>","DOI":"10.1177\/03913988231209010","type":"journal-article","created":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T01:33:35Z","timestamp":1698802415000},"page":"636-643","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Effects of biventricular shunt on pump characteristics in a maglev total artificial heart"],"prefix":"10.1177","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6573-5935","authenticated-orcid":false,"given":"Shuya","family":"Shida","sequence":"first","affiliation":[{"name":"Faculty of Science and Engineering, Toyo University, Kawagoe, Saitama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenichi","family":"Tsushima","sequence":"additional","affiliation":[{"name":"Graduate School of Science and Engineering, Ibaraki University, Hitachi, Ibaraki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Osa","sequence":"additional","affiliation":[{"name":"Graduate School of Science and Engineering, Ibaraki University, Hitachi, Ibaraki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel L","family":"Timms","sequence":"additional","affiliation":[{"name":"BiVACOR, Inc., Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toru","family":"Masuzawa","sequence":"additional","affiliation":[{"name":"Graduate School of Science and Engineering, Ibaraki University, Hitachi, Ibaraki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,10,31]]},"reference":[{"key":"bibr1-03913988231209010","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpa.2012.03.006"},{"key":"bibr2-03913988231209010","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2003.07.026"},{"key":"bibr3-03913988231209010","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2003.07.023"},{"key":"bibr4-03913988231209010","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa040186"},{"key":"bibr5-03913988231209010","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2003.07.024"},{"key":"bibr6-03913988231209010","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2009.05.035"},{"key":"bibr7-03913988231209010","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2009.05.034"},{"key":"bibr8-03913988231209010","doi-asserted-by":"publisher","DOI":"10.1109\/TBME.2009.2033389"},{"key":"bibr9-03913988231209010","unstructured":"ANSYS, Inc. 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