{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T16:35:39Z","timestamp":1787934939884,"version":"build-2784847793"},"reference-count":20,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Artif Organs"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>There has been an exponential increase in the utilization of temporary mechanical support devices for bridging Status 2 heart transplant candidates. The aim of our study is to determine outcomes in dual organ heart\/kidney recipients for patients bridged with an Impella 5.5 versus IABP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We evaluated the UNOS database and analyzed Status 2 patients who underwent dual organ heart\/kidney transplantation after being bridged with an Impella 5.5 or IABP from October 2019 (time of Impella 5.5 FDA approval) until March 2024.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 457 patients who underwent Heart\/Kidney transplant (HKT) were identified, of which 73% (334\/457) were bridged with an IABP and 27% (123\/457) with an Impella 5.5. Within the IABP cohort, 37% (122\/334) were on dialysis pre-transplant compared to 43% (53\/123) in the Impella group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.409). Patients in the Impella group had worse functional status, liver function, and filling pressures. There was no difference in the need for dialysis post-transplant (32% vs 29%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.613). Survival at 30, 180, and 360\u2009days and the rates of primary graft dysfunction, acute, and chronic rejection were similar between the two groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Both IABP and Impella appear to be safe for bridging dual organ heart and kidney transplant candidates, with comparable post-transplant heart and kidney graft function, complications, and survival up to 2\u2009years. Patients receiving Impella 5.5 appear to be sicker and as a result, this percutaneous temporary mechanical circulatory support device may confer some advantages, especially for patients with dual organ failure who undergo transplantation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03913988251334952","type":"journal-article","created":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T04:42:07Z","timestamp":1747370527000},"page":"325-331","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Impella 5.5 versus intra-aortic balloon pump for bridging dual organ heart-kidney transplants: Analysis of the UNOS database"],"prefix":"10.1177","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4877-1683","authenticated-orcid":false,"given":"Athanasios","family":"Tsiouris","sequence":"first","affiliation":[{"name":"Department of Surgery, Division of Cardiac Surgery, University of Mississippi Medical Center, Jackson, MS, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel A","family":"Hernandez","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, University of Mississippi Medical Center, Jackson, MS, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seth T","family":"Lirette","sequence":"additional","affiliation":[{"name":"Department of Data Science, University of Mississippi Medical Center, Jackson, MS, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashok Kumar","family":"Coimbatore Jeyakumar","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Cardiac Surgery, University of Mississippi Medical Center, Jackson, MS, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lampros","family":"Papadimitriou","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, University 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