{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T05:03:44Z","timestamp":1777784624480,"version":"3.51.4"},"reference-count":37,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Polish National Science Center","award":["2017\/27\/B\/ST7\/03029"],"award-info":[{"award-number":["2017\/27\/B\/ST7\/03029"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Artif Organs"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The concentration of bicarbonate in dialysis fluid (Dbic) that regulates acid-base balance in dialyzed patients is individually adjusted and may be modified during a hemodialysis session. We evaluated the impact of modifications of Dbic on plasma electrolytes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Two midweek hemodialysis sessions were monitored in 25 anuric, prevalent hemodialysis patients (67.9\u2009\u00b1\u20099.3\u2009years old, 32% females). During the first session (treatment A) Dbic was constant at 33.6\u2009\u00b1\u20091.7\u2009mmol\/L, while for the second week (treatment B) it was on average 30.8\u2009\u00b1\u20092.3\u2009mmol\/L for the initial 2\u2009h and 34.0\u2009\u00b1\u20092.5\u2009mmol\/L for the last 2\u2009h.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>During treatments A and B plasma bicarbonate (Pbic) increased during the sessions and was lower for treatment B than A at 60 and 120\u2009min of dialysis. Plasma chloride decreased during treatments A and B and was significantly higher at 60 and 120\u2009min of dialysis in treatment B than in treatment A. An increase of plasma calcium was observed during both treatments and it was higher for treatment B than A at 60 and 120\u2009min. A similar profile of plasma sodium and potassium was observed during treatments A and B. The difference in Pbic correlated positively, whereas the differences in plasma chloride and calcium correlated negatively, with the difference in Dbic between treatments B and A.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Modifications of dialysate bicarbonate may influence the concentrations of some other electrolytes in plasma; for each percent of Dbic increase one may expect \u22120.27 and \u22120.16% change in plasma chloride and calcium, respectively.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03913988251337323","type":"journal-article","created":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T05:13:37Z","timestamp":1747890817000},"page":"293-301","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Change in plasma electrolyte concentrations during hemodialysis following a controlled step-up in dialysate bicarbonate concentration"],"prefix":"10.1177","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8741-7930","authenticated-orcid":false,"given":"Malgorzata","family":"Debowska","sequence":"first","affiliation":[{"name":"Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"Wieliczko","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Dialysis and Internal Disease, Medical University of Warsaw, Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8224-783X","authenticated-orcid":false,"given":"Mauro","family":"Pietribiasi","sequence":"additional","affiliation":[{"name":"Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Urszula","family":"Bialonczyk","sequence":"additional","affiliation":[{"name":"Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jolanta","family":"Malyszko","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Dialysis and Internal Disease, Medical University of Warsaw, Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6811-3472","authenticated-orcid":false,"given":"John K","family":"Leypoldt","sequence":"additional","affiliation":[{"name":"Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacek","family":"Waniewski","sequence":"additional","affiliation":[{"name":"Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,5,22]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.00010505"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(04)00936-9"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/sdi.12454"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2016070780"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbe.2024.10.002"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1109\/ACCESS.2022.3147261"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/aor.12947"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1594.2012.01524.x"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/aor.13929"},{"key":"e_1_3_2_11_2","volume-title":"Handbook of dialysis","author":"Daugirdas J","year":"2003","unstructured":"Daugirdas J, Blake P, Ing T. 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