{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T04:23:08Z","timestamp":1783052588379,"version":"3.54.6"},"reference-count":24,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Artif Organs"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To compare the effect of hemofiltration (HF) versus hemodialysis (HD) on mortality and filter lifespan in patients with acute kidney injury (AKI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Literature published between January 1990 and December 2025 was retrieved from four databases: PubMed, Embase, MEDLINE, and China National Knowledge Infrastructure (CNKI). Statistical analyses were performed using Review Manager (RevMan) software.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Eight randomized controlled trials were included. HD showed no statistically significant difference in all-cause mortality compared to HF (RR\u2009=\u20091.07, 95% CI: 0.82\u20131.40). In subgroup analyses, continuous renal replacement therapy hemodialysis (CRRT-HD) showed no statistically significant difference in mortality compared to HF (RR\u2009=\u20091.05, 95% CI: 0.80\u20131.39;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.71), nor did intermittent hemodialysis (IHD; RR\u2009=\u20091.19, 95% CI: 0.96\u20131.49;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.12). Regarding filter lifespan, no significant difference was found in the overall analysis (SMD\u2009=\u20090.46, 95% CI: \u22120.29 to 1.22). However, in a single study under matched treatment doses, HD significantly prolonged filter lifespan (SMD\u2009=\u20091.00, 95% CI: 0.47\u20131.53). No significant difference was found between HDF and HF (SMD\u2009=\u2009\u22120.10, 95% CI: \u22120.37 to 0.18).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Current evidence shows no significant difference in mortality between HF and HD for AKI. Under matched doses, HD showed a significant advantage in prolonging filter lifespan, but this finding is based on a single study and requires confirmation. The evidence remains limited, highlighting the need for large-scale trials to assess patient-centered outcomes and operational indicators like filter lifespan.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03913988261427372","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T06:08:17Z","timestamp":1773641297000},"page":"155-166","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of the impact of hemodialysis versus hemofiltration on filter lifespan in acute kidney injury: A meta-analysis"],"prefix":"10.1177","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-2597-9595","authenticated-orcid":false,"given":"Qiaojiao","family":"Hua","sequence":"first","affiliation":[{"name":"Department of Emergency, Hangzhou First People\u2019s Hospital Affiliated to West Lake University School of Medicine, Hangzhou, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luhua","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Hangzhou First People\u2019s Hospital Affiliated to West Lake University School of Medicine, Hangzhou, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijun","family":"Zhong","sequence":"additional","affiliation":[{"name":"Department of Emergency, Hangzhou First People\u2019s Hospital Affiliated to West Lake University School of Medicine, Hangzhou, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinbo","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Oncology, Hangzhou First People\u2019s Hospital Affiliated to West Lake University School of Medicine, Hangzhou, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,3,15]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)02385-7"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2023.1104787"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.2174\/1871526519666190617154137"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.2147\/RMHP.S401205"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.30599"},{"issue":"2","key":"e_1_3_2_7_2","article-title":"Low-volume home haemodialysis and in-centre haemodialysis: comparison of dialysis adequacy in obese individuals","volume":"15","author":"Alalwan AA","year":"2023","unstructured":"Alalwan AA, Abou Trabeh A, Ahamed MMS, et al. 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Comparing renal replacement therapy modalities in critically ill patients with acute kidney injury: a systematic review and network meta-analysis. Crit Care Explor 2021; 3(5): e0399.","journal-title":"Crit Care Explor"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2018.09.004"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/sdi.12967"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/hdi.12545"},{"issue":"9831","key":"e_1_3_2_24_2","first-page":"2254","article-title":"Extracorporeal organ support in critical illness","volume":"379","author":"Bouman CS","year":"2012","unstructured":"Bouman CS, van der Hoeven JG, Pickkers P. Extracorporeal organ support in critical illness. 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