{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T10:12:31Z","timestamp":1775815951203,"version":"3.50.1"},"reference-count":26,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2021,12,29]],"date-time":"2021-12-29T00:00:00Z","timestamp":1640736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Urologia"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:sec><jats:title>Introduction:<\/jats:title><jats:p> Varicocele is among the most frequently encountered, surgically correctable causes of male infertility. Since varicocele is a primary abnormality of testicular vessels, a thorough understanding of haemodynamic changes in the microcirculation of varicocele testis is needed. <\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives:<\/jats:title><jats:p> To estimate changes in the microcirculation of varicocele testis and correlate them with symptomatic and semen parameters changes before and after varicocelectomy. <\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods:<\/jats:title><jats:p> This prospective, observational study includes 47 patients of age group 18\u201340\u2009years who underwent microsurgical varicocelectomy during June 2016 to April 2018 at a tertiary medical institute. Testicular haemodynamic was evaluated using a colour spectral doppler study (PSV-Peak systolic velocity\/ESV-End diastolic velocity\/RI-Resistive index\/PI-Pulsatility index). Semen analysis parameters and testicular blood flow were compared with pre-operative values. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> RI in the capsular artery of varicocele affected testis, which was 0.61\u2009\u00b1\u20090.11 (mean\u2009\u00b1\u2009SD), significantly reduced to 0.56\u2009\u00b1\u20090.09 (mean\u2009\u00b1\u2009SD) in post-operative follow-up, indicating improved perfusion. Pre-operative sperm density was noted to be 15.94\u2009\u00b1\u20097.88 (mean\u2009\u00b1\u2009SD), which improved to 28.41\u2009\u00b1\u200910.99, Progressive sperm motility from 33.81\u2009\u00b1\u200910.88 to 38.32\u2009\u00b1\u20099.21 and morphology from 36.13\u2009\u00b1\u200910.68 to 41.43\u2009\u00b1\u20099.29 on 6-month follow-ups ( p\u2009&lt;\u20090.05). <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> Varicocele testis is associated with altered testicular haemodynamic, which insults spermatogenesis. Microsurgical varicocelectomy with testicular artery and lymphatic preservation leads to correction of this altered haemodynamic state and improves the testicular microcirculation. <\/jats:p><\/jats:sec>","DOI":"10.1177\/03915603211069013","type":"journal-article","created":{"date-parts":[[2021,12,29]],"date-time":"2021-12-29T09:20:19Z","timestamp":1640769619000},"page":"164-169","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Estimation of haemodynamic changes in varicocele testis and results after microsurgical sub-inguinal varicocelectomy"],"prefix":"10.1177","volume":"90","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1925-5412","authenticated-orcid":false,"given":"Satyadeo","family":"Sharma","sequence":"first","affiliation":[{"name":"Department of Urology, All India Institute of Medical Sciences, Raipur, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajendra K","family":"Shimpi","sequence":"additional","affiliation":[{"name":"Department of Urology, Ruby Hall Clinic, Pune, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,12,29]]},"reference":[{"key":"bibr1-03915603211069013","doi-asserted-by":"publisher","DOI":"10.1016\/S0094-0143(02)00075-7"},{"key":"bibr2-03915603211069013","doi-asserted-by":"publisher","DOI":"10.4103\/1008-682X.172640"},{"key":"bibr3-03915603211069013","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2005.11.023"},{"key":"bibr4-03915603211069013","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2010.10030.x"},{"key":"bibr5-03915603211069013","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)38451-3"},{"key":"bibr6-03915603211069013","doi-asserted-by":"publisher","DOI":"10.15557\/JoU.2016.0036"},{"key":"bibr7-03915603211069013","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.20331"},{"key":"bibr8-03915603211069013","doi-asserted-by":"publisher","DOI":"10.1159\/000471687"},{"key":"bibr9-03915603211069013","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.152.2.293"},{"key":"bibr10-03915603211069013","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)32711-8"},{"key":"bibr11-03915603211069013","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2007.01.057"},{"issue":"4","key":"bibr12-03915603211069013","first-page":"231","volume":"33","author":"Dubin L","year":"1988","journal-title":"Int J Fertil"},{"key":"bibr13-03915603211069013","unstructured":"World Health Organization Department of Reproductive Health and Research. WHO laboratory manual for the examination and processing of human semen. Geneva: World Health Organization, 2010. pp.287."},{"key":"bibr14-03915603211069013","doi-asserted-by":"publisher","DOI":"10.2164\/jandrol.109.009977"},{"key":"bibr15-03915603211069013","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2005.12.033"},{"key":"bibr16-03915603211069013","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.20439"},{"key":"bibr17-03915603211069013","unstructured":"Krupin VN, Mamonov \u041cV. 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