{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T18:51:12Z","timestamp":1788375072824,"version":"build-2803163510"},"reference-count":26,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T00:00:00Z","timestamp":1710460800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Urologia"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:sec><jats:title>Background:<\/jats:title><jats:p> It is important to note that the causative agents and patterns of antibiotic resistance vary between urinary tract infections (UTIs) acquired in the community and those acquired in a hospital setting. Therefore, the aim of this study was to compare the types of organisms and patterns of antibiotic resistance in adult patients with community-acquired urinary tract infections (CA-UTIs) and hospital-acquired urinary tract infections (HA-UTIs). <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> Retrospectively, we collected urine samples from patients at An-Najah National University Hospital who experienced nonrecurring urinary tract infections (UTIs) between January 2019 and December 2020. The data were subsequently analyzed using IBM-SPSS<jats:sup>\u00ae<\/jats:sup> 21.0 software to determine the distribution of microorganisms and evaluate the rates of antibiotic resistance. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> A total of 798 nonrepetitive UTI patients were included in our study, in which more than half of the UTIs occurred in female patients (472; 59.1%), and most of the UTIs were of community origin (611; 76.6%). Both community-acquired urinary tract infections (CA-UTIs) and hospital-acquired urinary tract infections (HA-UTIs) were more common in female patients (45.6% and 13.5%, respectively). Escherichia coli was the most commonly isolated urinary pathogen in both the CA-UTIs and HA-UTIs. The five most common isolated urinary pathogens were E. coli, Klebsiella pneumoniae, Enterococcus faecalis, E. faecium, and Pseudomonas aeruginosa. Among the isolated bacteria, 28.2% were extended-spectrum beta-lactamase (ESBL)-producing bacteria, 4.1% were carbapenem-resistant Enterobacterales (CRE), and 6.5% were vancomycin-resistant Enterococci. The most commonly isolated urinary pathogens from HA-UTIs showed higher resistance rates against all the tested antibiotics except for E. faecium, which showed greater resistance to tetracycline (42.5%) and quinupristin\/dalfopristin (17.5%) in CA-UTIs. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p> There are similarities in the etiological profiles of CA-UTI and HA-UTI, but the resistance rates are high, and urine culture is essential for the correct treatment of individual cases, even in primary care. <\/jats:p><\/jats:sec>","DOI":"10.1177\/03915603241236361","type":"journal-article","created":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T12:53:35Z","timestamp":1710507215000},"page":"394-402","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Spectrum and antibiotic resistance in community- and hospital-acquired urinary tract infections among adults: Experience from a large tertiary care center in a developing country"],"prefix":"10.1177","volume":"91","author":[{"given":"Aya","family":"Herbawi","sequence":"first","affiliation":[{"name":"Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2889-1138","authenticated-orcid":false,"given":"Adham","family":"Abu Taha","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine"},{"name":"Department of Pathology, An-Najah National University Hospital, Nablus, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Banan M.","family":"Aiesh","sequence":"additional","affiliation":[{"name":"Department of Infection Control, An-Najah National University Hospital, Nablus, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Sabateen","sequence":"additional","affiliation":[{"name":"Department of Infection Control, An-Najah National University Hospital, Nablus, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sa\u2019ed H.","family":"Zyoud","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine"},{"name":"Clinical Research Center, An-Najah National University Hospital, Nablus, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,3,15]]},"reference":[{"key":"bibr1-03915603241236361","doi-asserted-by":"crossref","DOI":"10.1177\/1756287219832172","volume":"11","author":"Medina M","year":"2019","journal-title":"Ther Adv Urol"},{"key":"bibr2-03915603241236361","doi-asserted-by":"publisher","DOI":"10.1159\/000049840"},{"key":"bibr3-03915603241236361","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2010.11.005"},{"key":"bibr4-03915603241236361","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2019.02.007"},{"key":"bibr5-03915603241236361","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2012.09.015"},{"key":"bibr6-03915603241236361","first-page":"17","volume":"43","author":"Mancini A","year":"2020","journal-title":"New Microbiol"},{"key":"bibr7-03915603241236361","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2014.06.013"},{"key":"bibr8-03915603241236361","doi-asserted-by":"publisher","DOI":"10.1086\/423844"},{"key":"bibr9-03915603241236361","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2008.03.002"},{"key":"bibr10-03915603241236361","unstructured":"Clinical and Laboratory Standards Institute: performance standards for antimicrobial susceptibility testing: 20th informational supplement. 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