{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T19:44:26Z","timestamp":1780083866933,"version":"3.54.0"},"reference-count":50,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T00:00:00Z","timestamp":1724284800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100009388","name":"Jazan University","doi-asserted-by":"publisher","award":["ISP-23-82"],"award-info":[{"award-number":["ISP-23-82"]}],"id":[{"id":"10.13039\/100009388","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Urologia"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:p> This study systematically reviewed the scientific literature on natural remedies for male sexual dysfunction (MSD), including conditions like erectile dysfunction, premature ejaculation, and reduced libido. Limited scientific evidence exists regarding the efficacy and safety of these natural products. To ensure an objective assessment, the study used the Scopus database, followed the PRISMA guidelines, and employed a comprehensive search strategy involving relevant vital concepts, controlled vocabularies, and specific inclusion\/exclusion criteria. The analysis included 1504 documents from 624 journals, spanning from 1967 to 2023. The literature showed an annual growth rate of 2.46%, with an average document age of 10.2\u2009years and an average of 23.54 citations per document. India had the highest publication count (319), followed by the United States (164). Conceptual Mapping categorized themes into basic, motor, niche, emerging, and declining categories, including nitric oxide, oxidative stress, phytotherapy, herbal medicine, Asparagus racemosus, and dopamine. This mapping provided a holistic understanding of the field, identified research gaps, and guided the development of new interventions or treatment strategies for MSD. Trend topics include molecular coupling, Ashwagandha, phytochemistry, phosphodiesterase-5, and arginase. The study findings will assist healthcare professionals in making informed decisions when recommending or advising patients about the use of these remedies. <\/jats:p>","DOI":"10.1177\/03915603241273882","type":"journal-article","created":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T18:20:58Z","timestamp":1724350858000},"page":"647-658","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["A systematic literature review of natural products for male sexual dysfunction"],"prefix":"10.1177","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6145-4466","authenticated-orcid":false,"given":"Siddig Ibrahim","family":"Abdelwahab","sequence":"first","affiliation":[{"name":"Health Research Centre, Jazan University, Jazan, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manal Mohamed Elhassan","family":"Taha","sequence":"additional","affiliation":[{"name":"Health Research Centre, Jazan University, Jazan, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,8,22]]},"reference":[{"key":"bibr1-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1038\/aja.2010.135"},{"key":"bibr2-03915603241273882","first-page":"28","volume":"503","author":"Rew KT","year":"2021","journal-title":"FP essentials"},{"key":"bibr3-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2019.106495"},{"key":"bibr4-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1016\/j.pop.2019.02.006"},{"key":"bibr5-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1016\/S0094-0143(05)70137-3"},{"key":"bibr6-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2016.09.018"},{"key":"bibr7-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1016\/j.ucl.2022.02.001"},{"key":"bibr8-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2020.113536"},{"key":"bibr9-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2019.01.046"},{"issue":"1","key":"bibr10-03915603241273882","first-page":"3","volume":"68","author":"Malviya N","year":"2011","journal-title":"Acta Pol Pharm"},{"key":"bibr11-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6882-10-44"},{"issue":"4","key":"bibr12-03915603241273882","volume":"4","author":"Lee HW","year":"2021","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr13-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1186\/1742-5581-3-1"},{"key":"bibr14-03915603241273882","doi-asserted-by":"publisher","DOI":"10.54724\/lc.2022.e9"},{"key":"bibr15-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.12767"},{"issue":"10","key":"bibr16-03915603241273882","volume":"15","author":"Dagli N","year":"2023","journal-title":"Cureus"},{"key":"bibr17-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1186\/s13148-023-01603-9"},{"key":"bibr18-03915603241273882","doi-asserted-by":"publisher","DOI":"10.5195\/jmla.2022.1434"},{"issue":"1","key":"bibr19-03915603241273882","first-page":"141","volume":"67","author":"Pritish Baskaran TB","year":"2023","journal-title":"Indian J Public Health"},{"issue":"3","key":"bibr20-03915603241273882","first-page":"189","volume":"38","author":"B\u00e9rdi M","year":"2023","journal-title":"Psychiatr Hung"},{"key":"bibr21-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0045(199610)29:4<231::AID-PROS4>3.0.CO;2-E"},{"key":"bibr22-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1111\/j.1745-7262.2005.00052.x"},{"key":"bibr23-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(99)00549-X"},{"issue":"5","key":"bibr24-03915603241273882","first-page":"345","volume":"3","author":"Ugulu I","year":"2009","journal-title":"J Med Plants Res"},{"key":"bibr25-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2007.11.011"},{"key":"bibr26-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1016\/S0024-3205(02)01858-1"},{"key":"bibr27-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2005.12.015"},{"key":"bibr28-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2008.09.004"},{"key":"bibr29-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2006.02.012"},{"key":"bibr30-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2009.04.005"},{"key":"bibr31-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-020-09284-0"},{"key":"bibr32-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-02511-3_10"},{"issue":"1","key":"bibr33-03915603241273882","first-page":"41","volume":"52","author":"Nicol A","year":"2023","journal-title":"Aust J Gen Pr"},{"key":"bibr34-03915603241273882","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2023.1148834"},{"key":"bibr35-03915603241273882","doi-asserted-by":"publisher","DOI":"10.21037\/tau.2016.11.13"},{"key":"bibr36-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1016\/j.scp.2021.100484"},{"key":"bibr37-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1007\/BF02975191"},{"key":"bibr38-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9422(01)00480-0"},{"key":"bibr39-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.968"},{"key":"bibr40-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1046\/j.1472-8206.2002.00106.x"},{"key":"bibr41-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1515\/JBCPP.2003.14.3.301"},{"key":"bibr42-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1538\/expanim.46.287"},{"key":"bibr43-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.21.153"},{"key":"bibr44-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1007\/BF02976776"},{"key":"bibr45-03915603241273882","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27123799"},{"issue":"3","key":"bibr46-03915603241273882","first-page":"312","volume":"10","author":"Ehigiator B","year":"2022","journal-title":"J Trop Dis"},{"issue":"2","key":"bibr47-03915603241273882","first-page":"91","volume":"2","author":"Badgal E","year":"2023","journal-title":"Sci Phytochem"},{"key":"bibr48-03915603241273882","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28176314"},{"key":"bibr49-03915603241273882","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2022.116064"},{"key":"bibr50-03915603241273882","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11133732"}],"container-title":["Urologia Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03915603241273882","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03915603241273882","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03915603241273882","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T20:22:49Z","timestamp":1741033369000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03915603241273882"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,22]]},"references-count":50,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1177\/03915603241273882"],"URL":"https:\/\/doi.org\/10.1177\/03915603241273882","relation":{},"ISSN":["0391-5603","1724-6075"],"issn-type":[{"value":"0391-5603","type":"print"},{"value":"1724-6075","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,22]]}}}