{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T02:50:39Z","timestamp":1788922239631,"version":"build-2803163510"},"reference-count":39,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T00:00:00Z","timestamp":1739491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Urologia"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:sec>\n            <jats:title>Objective:<\/jats:title>\n            <jats:p>The present study aimed to compare the effects of suppository diclofenac (an example of NSAIDs) and oral administration of the combination of oxycodone (an example of an opioid) and acetaminophen in managing pain in patients with renal colic after SWL treatment.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Method:<\/jats:title>\n            <jats:p>The current study is a double-blind clinical trial involving individuals scheduled to receive elective SWL therapy for kidney and ureteral stones. Participants were randomly assigned to one of two groups using the block randomization technique: suppository Diclofenac (100\u2009mg) or a combination of 325\u2009mg Acetaminophen\u2009+\u20095\u2009mg oxycodone administered orally for pain relief following SWL. Pain intensity was measured immediately after the SWL procedure, and analgesics were then given to the patients. After 30\u2009min, pain severity was reassessed. The severity of pain in patients was documented before and after drug administration at 24, 48, and 72\u2009h after the SWL intervention.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>\n              154 renal stone patients (63 females) underwent SWL with a mean age of 41.52\u2009\u00b1\u200910.52\u2009years. The two groups were similar in terms of age (\n              <jats:italic>p<\/jats:italic>\n              \u2009=\u20090.572), sex (\n              <jats:italic>p<\/jats:italic>\n              \u2009=\u20090.212), location of the stone (\n              <jats:italic>p<\/jats:italic>\n              \u2009=\u20090.868), size of the stone (\n              <jats:italic>p<\/jats:italic>\n              \u2009=\u20090.762), and occurrence of complication (\n              <jats:italic>p<\/jats:italic>\n              \u2009=\u20090.302). There was no significant difference in the reduction of pain severity between the two groups after 30\u2009min (\n              <jats:italic>p<\/jats:italic>\n              \u2009=\u20090.224), 2\u2009days (\n              <jats:italic>p<\/jats:italic>\n              \u2009=\u20090.501), and 3\u2009days (\n              <jats:italic>p<\/jats:italic>\n              \u2009=\u20090.229) following SWL intervention. However, after a 24-h follow-up, pain severity decreased more in the diclofenac group compared to the other group (\n              <jats:italic>p<\/jats:italic>\n              \u2009=\u20090.002).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion:<\/jats:title>\n            <jats:p>The combination of oxycodone and acetaminophen, including a multimodal analgesic approach, can be considered a preferred option in the clinical setting for pain management of patients undergoing SWL. It provides relief for patients as effectively as NSAIDs, with the same safety profile, leading to high patient satisfaction.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1177\/03915603251317046","type":"journal-article","created":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T05:42:36Z","timestamp":1739511756000},"page":"439-445","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Evaluation of the analgesic effect of a combination of oral acetaminophen and oxycodone after extracorporeal shock wave lithotripsy (SWL)"],"prefix":"10.1177","volume":"92","author":[{"given":"Leila","family":"Zareian Baghdadabad","sequence":"first","affiliation":[{"name":"Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdolreza","family":"Mohammadi","sequence":"additional","affiliation":[{"name":"Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2983-0485","authenticated-orcid":false,"given":"Iman","family":"Menbari Oskouie","sequence":"additional","affiliation":[{"name":"Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farshid","family":"Alaeddini","sequence":"additional","affiliation":[{"name":"Tehran Heart Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirad","family":"Farajidavar","sequence":"additional","affiliation":[{"name":"Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran"},{"name":"Department of Clinical Pharmacy, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2092-414X","authenticated-orcid":false,"given":"Leonardo","family":"Oliveira Reis","sequence":"additional","affiliation":[{"name":"UroScience and Department of Surgery (Urology), School of Medical Sciences, University of Campinas, Unicamp, and Pontifical Catholic University of Campinas, PUC-Campinas, Campinas, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1611-0362","authenticated-orcid":false,"given":"Seyed Mohammad Kazem","family":"Aghamir","sequence":"additional","affiliation":[{"name":"Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,2,14]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1590\/s1677-5538.ibju.2016.0630"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2021.102829"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.207.2.9577473"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2015.04.010"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.4111\/kju.2015.56.1.56"},{"issue":"4","key":"e_1_3_3_7_2","first-page":"127","article-title":"A comparison of minimally invasive surgery ureterolithotomy and transurethral lithotripsy in combination with retrograde intrarenal surgery: a randomized clinical trial","volume":"2","author":"Aghamir SMK","year":"2020","unstructured":"Aghamir SMK, Khorrami MH, Saatchi M, et al. 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