{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T22:08:45Z","timestamp":1773958125128,"version":"3.50.1"},"reference-count":28,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2025,2,16]],"date-time":"2025-02-16T00:00:00Z","timestamp":1739664000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Urologia"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:sec>\n            <jats:title>Purpose:<\/jats:title>\n            <jats:p>To evaluate the association of traditional and novel nutritional measurements with survival in Fournier\u2019s gangrene (FG) patients.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>We reviewed records of FG patients from our tertiary center (Jan 2013\u2013Jan 2022). Radiomic sarcopenia parameters (Psoas Muscle Area [PMA], Roundness, Solidity, and calculated PMA-Index) were measured from admission CT scans at the L3 level using ImageJ software. We assessed sarcopenia\u2019s impact on survival through three analyses: Model 1 used a PMI below the sex-adjusted median; Models 2 and 3 used published cutoffs. Kaplan-Meier curves were used to compare survival between sarcopenic and non-sarcopenic patients. Multivariable Cox and logistic regression analyses adjusted for age and the Charlson Comorbidity Index (CCI) to assess mortality risk.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>\n              Of 130 men and 31 women (82% white), 60 patients (37.3%) had died after a median follow-up of 2.2\u2009years (IQR 0.9-4.4). Survival rates were 94% at 30\u2009days, 92% at 90\u2009days, 80% at 1 year, 77% at 2\u2009years, and 56% at 5\u2009years. Non-survivors were older (median age 63 vs 55.1\u2009years,\n              <jats:italic>p<\/jats:italic>\n              \u2009&lt;\u20090.001) and had higher median CCI (4.8 vs 3;\n              <jats:italic>p<\/jats:italic>\n              \u2009&lt;\u20090.001).\n            <\/jats:p>\n            <jats:p>\n              In Model 1, sarcopenic patients had a non-significant increased mortality risk with hazard ratio (HR 1.47, 95% CI 0.82\u20132.64,\n              <jats:italic>p<\/jats:italic>\n              \u2009=\u20090.196). Models 2 and 3 showed similar results (HR 1.41, 95% CI 0.70\u20132.84,\n              <jats:italic>p<\/jats:italic>\n              \u2009=\u20090.325; HR 1.35, 95% CI 0.70\u20132.61,\n              <jats:italic>p<\/jats:italic>\n              \u2009=\u20090.364). None of the models were significant when adjusting for CCI and age. Survivors had better traditional metabolic profiles, including higher albumin (3.1vs 2.7\u2009g\/dL), hemoglobin (12.4vs 11.4\u2009g\/dL), and lower creatinine (1.39 vs 2.1\u2009mg\/dL); however, none of these were significant when adjusting for age and CCI.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>Despite a mild trend, none of the sarcopenia models were able to predict long-term mortality in FG patients in our cohort. This well-known, cost-effective nutritional predictor still requires further research to optimize its utilization in the FG patient population.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1177\/03915603251318502","type":"journal-article","created":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T01:55:21Z","timestamp":1739757321000},"page":"484-492","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Harnessing radiomics and nutritional metrics to predict long-term survival in Fournier\u2019s gangrene patients"],"prefix":"10.1177","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4130-8987","authenticated-orcid":false,"given":"Kamil","family":"Malshy","sequence":"first","affiliation":[{"name":"The Minimally Invasive Urology Institute, The Miriam Hospital, Providence, RI, USA"},{"name":"Warren Alpert Medical School of Brown University, Providence, RI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Schmit","sequence":"additional","affiliation":[{"name":"Warren Alpert Medical School of Brown University, Providence, RI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Borivoj","family":"Golijanin","sequence":"additional","affiliation":[{"name":"The Minimally Invasive Urology Institute, The Miriam Hospital, Providence, RI, USA"},{"name":"Warren Alpert Medical School of Brown University, Providence, RI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Ahn","sequence":"additional","affiliation":[{"name":"Warren Alpert Medical School of Brown University, Providence, RI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Morgan","sequence":"additional","affiliation":[{"name":"The Minimally Invasive Urology Institute, The Miriam Hospital, Providence, RI, USA"},{"name":"Warren Alpert Medical School of Brown University, Providence, RI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Farah","sequence":"additional","affiliation":[{"name":"The Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kennon","family":"Miller","sequence":"additional","affiliation":[{"name":"The Minimally Invasive Urology Institute, The Miriam Hospital, Providence, RI, USA"},{"name":"Warren Alpert Medical School of Brown University, Providence, RI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dragan","family":"Golijanin","sequence":"additional","affiliation":[{"name":"The Minimally Invasive Urology Institute, The Miriam Hospital, Providence, RI, USA"},{"name":"Warren Alpert Medical School of Brown University, Providence, RI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madeline","family":"Cancian","sequence":"additional","affiliation":[{"name":"The Minimally Invasive Urology Institute, The Miriam Hospital, Providence, RI, USA"},{"name":"Warren Alpert Medical School of Brown University, Providence, RI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,2,16]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.18948"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1159\/000445695"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2005.042069"},{"key":"e_1_3_3_5_2","doi-asserted-by":"crossref","unstructured":"Zahid S Parker A. Nutrition management of the adult patient with necrotizing fasciitis. Top Clin Nutr 2024; 39(2). https:\/\/journals.lww.com\/topicsinclinicalnutrition\/fulltext\/2024\/04000\/nutrition_management_of_the_adult_patient_with.10.aspx","DOI":"10.1097\/TIN.0000000000000337"},{"key":"e_1_3_3_6_2","article-title":"Nutrition, anabolism, and the wound healing process: an overview","volume":"9","author":"Demling RH","year":"2009","unstructured":"Demling RH. Nutrition, anabolism, and the wound healing process: an overview. Eplasty 2009; 9: e9.","journal-title":"Eplasty"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpra.2024.01.006"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2021.07.017"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)31138-9"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afr051"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2012.350"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu13124471"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-018-2259-x"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11934-015-0548-0"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)67236-7"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.05.021"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2089"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00744.2004"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jceh.2022.12.002"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-52502-9"},{"key":"e_1_3_3_21_2","volume-title":"Python Reference Manual","author":"Van Rossum","year":"1995","unstructured":"Van Rossum, Guido, Drake FLJr. Python Reference Manual. Centrum voor Wiskunde en Informatica Amsterdam; 1995."},{"key":"e_1_3_3_22_2","unstructured":"DataTab Team. DataTab: online statistics calculator. Published online 2024. https:\/\/datatab.net"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1159\/000342407"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2077.104916"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2021.06.025"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1993.tb06940.x"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2006.01.030"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1177\/00031348231160840"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2022.01.036"}],"container-title":["Urologia Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03915603251318502","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03915603251318502","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03915603251318502","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T13:35:24Z","timestamp":1753450524000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03915603251318502"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,16]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["10.1177\/03915603251318502"],"URL":"https:\/\/doi.org\/10.1177\/03915603251318502","relation":{},"ISSN":["0391-5603","1724-6075"],"issn-type":[{"value":"0391-5603","type":"print"},{"value":"1724-6075","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,16]]}}}