{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T10:06:04Z","timestamp":1774346764092,"version":"3.50.1"},"reference-count":27,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2025,5,17]],"date-time":"2025-05-17T00:00:00Z","timestamp":1747440000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Urologia"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>This study aimed to assess the clinical outcomes of Fournier\u2019s gangrene and its predisposing factors in male diabetic and non-diabetic patients. We also evaluated the disease severity using the Fournier\u2019s Gangrene Severity Index and examined management outcomes, including mode of wound closure and complications related to the disease and treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Patients with Fournier\u2019s gangrene underwent admission, with detailed history collection. Disease severity was clinically and laboratory assessed. Empirical antibiotics preceded surgical management and microbial evaluation. Wound closure involved primary suturing, skin grafting, or flaps. Patients were called for regular follow-up after discharge, and complications were identified.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Our study has shown that the overall FGSI was much higher among diabetics as compared to non-diabetics, and the same goes for the mortality rate, which was much higher in diabetics, owing to the higher rate of complications among them. It was also found that the prognosis of Fournier\u2019s gangrene is worse among diabetics. The mean number of debridement\u2019s in the diabetic group (3.00\u2009\u00b1\u20091.016) was higher than the non-diabetic group (2.22\u2009\u00b1\u20091.003). The association between number of debridement\u2019s in the two groups was statistically significant (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Early diagnosis and aggressive management are crucial to reduce Fournier\u2019s gangrene mortality. Effective diabetic control and repeated debridement are necessary to successfully manage these complex cases.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03915603251338715","type":"journal-article","created":{"date-parts":[[2025,5,17]],"date-time":"2025-05-17T06:20:59Z","timestamp":1747462859000},"page":"713-720","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical spectrum and management of Fournier\u2019s gangrene among diabetics and non-diabetics: A comparative study"],"prefix":"10.1177","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-7208-7234","authenticated-orcid":false,"given":"Ashish","family":"Ranjan","sequence":"first","affiliation":[{"name":"Department of Urology and Renal Transplantation, Sanjay Gandhi Post-Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samrat","family":"Biswas","sequence":"additional","affiliation":[{"name":"Debra Super Speciality Hospital, Midnapore, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nidhi","family":"Bhatnagar","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Dr. Ram Manohar Lohia Hospital, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debabrata","family":"Kundu","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Medical College, Kolkata, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,5,17]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"Leslie SW Rad J Foreman J. Fournier gangrene. Treasure Island FL: StatPearls Publishing. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK549821\/ (2024 accessed 5 June 2023)."},{"key":"e_1_3_3_3_2","first-page":"353","article-title":"Fournier gangrene in the emergency department: diagnostic dilemmas, treatments and current perspectives","volume":"12","author":"Auerbach J","year":"2020","unstructured":"Auerbach J, Bornstein K, Ramzy M, et al. Fournier gangrene in the emergency department: diagnostic dilemmas, treatments and current perspectives. 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