{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T16:23:39Z","timestamp":1790871819778,"version":"4.1.0"},"reference-count":16,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Urologia"],"published-print":{"date-parts":[[2025,11]]},"abstract":"\n Introduction:<\/jats:title>\n Medical expulsive therapy (MET) has been shown to be a safe and effective option for the spontaneous passage of uncomplicated ureteric stones sizing\u2009\u2a7d10\u2009mm in selected cases. However, there is lack of evidence on the predictors of successful MET. Our objective was to identify parameters that can accurately predict the spontaneous passage of ureteral stones during MET.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n Patients receiving MET (Tamsulosin 0.4\u2009mg once daily (OD)) for a single unilateral ureteral calculi sizing\u2009\u2a7d10\u2009mm were followed after 1\u2009month using Non contrast Computed tomography (NCCT). Various parameters such as stone-related parameters (location, density, volume and transverse, longitudinal, and sagittal diameters), ureter-related parameters (diameter, density, and wall thickness at the stone site) and grade of hydronephrosis were evaluated on CT images and analyzed by using univariate, multivariate and receiver operating characteristic (ROC) curve analyses.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Of 55 patients, 31 (56.4%) passed the stone successfully within 4\u2009weeks of MET. Univariate analysis revealed these patients tended to have lower ureteric stones (\n p<\/jats:italic>\n -value- 0.048), lower longitudinal (\n p<\/jats:italic>\n -value- 0.024) and transverse stone diameters (\n p<\/jats:italic>\n -value- 0.006), lower stone volume (\n p<\/jats:italic>\n -value- 0.015) and ureteral wall thickness (UWT;\n p<\/jats:italic>\n -value- 0.001). In multivariate analysis, only UWT at the stone site (\n p<\/jats:italic>\n 0.036) was a significant predictor of the successful passage of calculus. The UWT cut-off was 2.1\u2009mm with sensitivity and specificity of 83.8% and 62.5%, respectively, with an Area Under Curve (AUC) of 0.7856.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n The most significant predictor of successful stone passage in MET of unilateral ureteral stones was maximal UWT, with an optimal cut-off point of 2.1\u2009mm.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/03915603251360160","type":"journal-article","created":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T08:38:47Z","timestamp":1755160727000},"page":"698-704","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Predictive CT-based parameters for successful medical expulsive therapy in unilateral ureteral calculi: A prospective observational study"],"prefix":"10.1177","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-5275-1899","authenticated-orcid":false,"given":"Viswas Raghavendra","family":"Marathi","sequence":"first","affiliation":[{"name":"Department of Urology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2752-6016","authenticated-orcid":false,"given":"Devashish","family":"Kaushal","sequence":"additional","affiliation":[{"name":"Department of Urology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9444-0271","authenticated-orcid":false,"given":"Kumar","family":"Madhavan","sequence":"additional","affiliation":[{"name":"Department of Urology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh","family":"Malik","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhineeth","family":"KP","sequence":"additional","affiliation":[{"name":"Department of Urology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,8,14]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2016.05.090"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2016.07.024"},{"issue":"4","key":"e_1_3_3_4_2","first-page":"641","article-title":"The role of alternative medicine and complimentary therapies in urologic disease: new horizons","volume":"91","author":"Bizzarri FP","year":"2024","unstructured":"Bizzarri FP, Campetella M, Ragonese M, et al. The role of alternative medicine and complimentary therapies in urologic disease: new horizons. Urol J 2024; 91(4): 641\u2013646.","journal-title":"Urol J"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.178.1.1780101"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000100960.08768.81"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1159\/000070133"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-018-2461-x"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1089\/end.2020.0645"},{"issue":"2","key":"e_1_3_3_10_2","first-page":"224","article-title":"Risk factors for benign uretero-enteric anastomotic strictures after open radical cystectomy and ileal conduit","volume":"92","author":"Bizzarri FP","year":"2025","unstructured":"Bizzarri FP, Campetella M, Russo P, et al. Risk factors for benign uretero-enteric anastomotic strictures after open radical cystectomy and ileal conduit. Urol J 2025; 92(2): 224\u2013230.","journal-title":"Urol J"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1089\/end.2009.0670"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.08.1545"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2016.11.046"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00240-015-0762-8"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00240-014-0724-6"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2017.04.047"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00240-020-01214-6"}],"container-title":["Urologia Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03915603251360160","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03915603251360160","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03915603251360160","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T06:24:09Z","timestamp":1774333449000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03915603251360160"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,14]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1177\/03915603251360160"],"URL":"https:\/\/doi.org\/10.1177\/03915603251360160","relation":{},"ISSN":["0391-5603","1724-6075"],"issn-type":[{"value":"0391-5603","type":"print"},{"value":"1724-6075","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,14]]}}}