{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T08:29:29Z","timestamp":1769675369232,"version":"3.49.0"},"reference-count":17,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T00:00:00Z","timestamp":1760486400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Urologia"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>Assessing the association between Testosterone (T)-level in patients with urethral stricture (US) and its effect on surgery outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This prospective study includes 70 cases of developing US disease and anastomotic Urethroplasty. All patients underwent retrograde and voiding urethrography, pelvi-abdominal ultrasound, and T (free and total) measurements.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A significant negative association was found between free T, age, and post-void residual volume (PVR) pre. Also, a positive association between free T and Hemoglobin (Hb) levels. Besides, an association between wound infection and total T. There was a significant lower in PVR and higher in Q-max post-urethroplasty than pre-urethroplasty. International prostate symptom score (IPSS) showed a significant decrease in post-urethroplasty and at 3\u2009months follow up than pre-urethroplasty (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Diabetes mellitus, free, and total T showed significant differences between the studied groups. Also, it can predict failure results respectively at cut-off\u2009\u2a7d123.75 and \u2a7d765.8 with 85.70% sensitivity, 98.40%, and 88.90% specificity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Diabetic status, wound infection, and free and total T significantly affect the success rate in patients with the US, while preoperative PVR, Q-max, and IPSS did not affect the success rate.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03915603251367566","type":"journal-article","created":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T13:42:13Z","timestamp":1760535733000},"page":"114-120","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of the relationship between testosterone level in patients with urethral stricture and its effect on outcome of surgery"],"prefix":"10.1177","volume":"93","author":[{"given":"Mohamed Abdelwahab","family":"Ismail","sequence":"first","affiliation":[{"name":"Urology Department, Faculty of Medicine, Cairo University, Cairo, Cairo Governorate, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-0488-5092","authenticated-orcid":false,"given":"Muhammed Abdullah Hussein","family":"Khedr","sequence":"additional","affiliation":[{"name":"Urology Department, Military Medical Academy, Cairo, Giza, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed Amr","family":"Lotfi","sequence":"additional","affiliation":[{"name":"Urology Department, Faculty of Medicine, Cairo University, Cairo, Cairo Governorate, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amr Abdelkhalek","family":"Elkady","sequence":"additional","affiliation":[{"name":"Urology Department, Faculty of Medicine, Cairo University, Cairo, Cairo Governorate, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,10,15]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/9046430"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12041495"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.5489\/cuaj.1661"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2017.10.057"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcte.2024.100365"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2017.02.037"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000133083.54934.ae"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.28042"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/andr.13554"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.21608\/eju.2024.240754.1006"},{"key":"e_1_3_3_12_2","first-page":"103178","article-title":"Dynamics of serum testosterone and biological aging in men: insights from Chinese, American, and British populations","volume":"82","author":"Huang W","year":"2025","unstructured":"Huang W, Deng L, Wen Q, et al. Dynamics of serum testosterone and biological aging in men: insights from Chinese, American, and British populations. med 2025; 82: 103178.","journal-title":"med"},{"key":"e_1_3_3_13_2","article-title":"Diabetic wound-healing science","volume":"57","author":"Burgess JL","year":"2021","unstructured":"Burgess JL, Wyant WA, Abdo Abujamra B, et al. Diabetic wound-healing science. Medicinar 2021; 57: 1072.","journal-title":"Medicinar"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1515\/hmbci-2015-0014"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61717-7"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2010.09800.x"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri2925"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-015-0972-6"}],"container-title":["Urologia Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03915603251367566","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03915603251367566","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03915603251367566","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T21:47:22Z","timestamp":1769636842000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03915603251367566"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,15]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1177\/03915603251367566"],"URL":"https:\/\/doi.org\/10.1177\/03915603251367566","relation":{},"ISSN":["0391-5603","1724-6075"],"issn-type":[{"value":"0391-5603","type":"print"},{"value":"1724-6075","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,15]]}}}