{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T05:04:01Z","timestamp":1789621441419,"version":"build-2803163510"},"reference-count":9,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Urologia"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Multiparametric magnetic resonance imaging (mp-MRI) has emerged as a promising technique for evaluating the extent of bladder cancer, particularly for assessing muscle invasion. The Vesical Imaging Reporting and Data System (VI-RADS), introduced in 2018, aims to standardize the interpretation of mp-MRI for staging bladder tumors. This study investigates the diagnostic accuracy of VI-RADS in predicting detrusor muscle involvement preoperatively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To assess the diagnostic performance of VI-RADS scoring in determining muscle invasion in bladder cancer patients prior to surgical intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This prospective study enrolled 62 patients between June 2021 and April 2023 who presented with bladder masses. Each underwent mp-MRI followed by surgical treatment, including either TURBT or radical cystectomy. Two radiologists independently evaluated images using VI-RADS scoring. The results were compared with final histopathological findings to determine diagnostic accuracy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>VI-RADS scores of 4 and 5 were observed in 10 (16%) and 19 (30.6%) patients respectively; scores of 3, 2, and 1 were assigned to 3 (4.8%), 25 (40.3%), and 5 (8.0%) patients, respectively. Histopathological evaluation confirmed muscle invasion in 29 patients (46.77%) and non-muscle-invasive disease in 33 (53.22%). The mp-MRI demonstrated a sensitivity of 93.10%, specificity of 93.94%, and an overall accuracy of 93.54% in detecting muscle invasion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Mp-MRI interpreted using the VI-RADS system offers more than 90% sensitivity and specificity for detecting muscle invasion in bladder cancer. VI-RADS may serves as a valuable tool for preoperative staging, potentially optimizing treatment planning and reducing unnecessary restaging TURBT.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03915603261429445","type":"journal-article","created":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T10:35:37Z","timestamp":1773398137000},"page":"364-369","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Diagnostic accuracy and reliability of VI-RADS in assessing muscle invasion in bladder cancer: Insight from a prospective tertiary care study"],"prefix":"10.1177","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-3277-6977","authenticated-orcid":false,"given":"Anupam","family":"Shukla","sequence":"first","affiliation":[{"name":"Department of Urology and Renal Transplantation, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Hiralal","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-5481-9860","authenticated-orcid":false,"given":"Himanshu","family":"Raj","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjoy","family":"Surekha","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uday Pratap","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplantation, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,3,13]]},"reference":[{"key":"e_1_3_2_2_2","unstructured":"Del Giudice F et al. Accuracy of the VI-RADS score for predicting muscle-invasive bladder cancer: results from a prospective study. Eur Radiol 2020; 30(10). 5404\u20135414. https:\/\/doi.org\/10.1007\/s00330-020-06912-9"},{"key":"e_1_3_2_3_2","unstructured":"Barchetti F et al. Multiparametric MRI of the bladder: interobserver agreement and accuracy using the VI-RADS score. Radiology 2019; 291(1). 117\u2013127. https:\/\/doi.org\/10.1148\/radiol.2019181920"},{"key":"e_1_3_2_4_2","unstructured":"Wang H et al. Diagnostic performance of VI-RADS for detecting muscle-invasive bladder cancer: a systematic review and meta-analysis. Eur Radiol 2021; 31(6). 4606\u20134616. https:\/\/doi.org\/10.1007\/s00330-020-07603-3"},{"key":"e_1_3_2_5_2","unstructured":"van der Pol CB et al. VI-RADS score for staging bladder cancer: a systematic review and meta-analysis of diagnostic accuracy. AJR Am J Roentgenol 2020; 215(6). 1234\u20131243. https:\/\/doi.org\/10.2214\/AJR.20.22942"},{"key":"e_1_3_2_6_2","unstructured":"Ueno Y et al. Usefulness of diffusion-weighted imaging and dynamic contrast-enhanced MRI for preoperative staging of bladder cancer. Eur Radiol 2018; 28(10). 4160\u20134169. https:\/\/doi.org\/10.1007\/s00330-018-5397-2"},{"key":"e_1_3_2_7_2","doi-asserted-by":"crossref","unstructured":"Takeuchi M et al. Differentiation of bladder tumor recurrence from post-treatment changes using multiparametric MRI. AJR Am J Roentgenol 2014; 202(3). W280\u2013W289. https:\/\/doi.org\/10.2214\/AJR.13.11327","DOI":"10.2214\/AJR.13.11327"},{"key":"e_1_3_2_8_2","unstructured":"Barentsz JO et al. Role of dynamic contrast-enhanced MRI in oncologic imaging: principles and clinical applications. Eur Radiol 2012; 22(9). 2016\u20132029. https:\/\/doi.org\/10.1007\/s00330-012-2462-8"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.21037\/tau-19-671"},{"key":"e_1_3_2_10_2","doi-asserted-by":"crossref","unstructured":"Panebianco V et al. Vesical Imaging\u2013Reporting and Data System (VI-RADS): standardized reporting for multiparametric MRI of the urinary bladder. Eur Urol 2018; 74(3). 294\u2013306. https:\/\/doi.org\/10.1016\/j.eururo.2018.04.014","DOI":"10.1016\/j.eururo.2018.06.029"}],"container-title":["Urologia Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03915603261429445","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03915603261429445","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03915603261429445","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T04:34:50Z","timestamp":1789619690000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03915603261429445"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,13]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1177\/03915603261429445"],"URL":"https:\/\/doi.org\/10.1177\/03915603261429445","relation":{},"ISSN":["0391-5603","1724-6075"],"issn-type":[{"value":"0391-5603","type":"print"},{"value":"1724-6075","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,13]]}}}