{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T18:31:52Z","timestamp":1788201112011,"version":"build-2803163510"},"reference-count":28,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Urologia"],"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To describe the clinical and epidemiological characteristics of patients diagnosed with penile cancer in a hospital-based cohort from southwestern Colombia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective cross-sectional study was conducted using medical records from the Urology Department of a tertiary hospital in Cali, Colombia, between January 2013 and February 2024. Patients with confirmed penile cancer were identified through ICD-10 codes. Sociodemographic, clinical, pathological, and treatment data were extracted and analyzed descriptively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Eighty-nine patients were included. The median age was 61\u2009years (range: 34\u201395), with most residing in Cali or nearby departments. At diagnosis, 53.2% had cT3-stage tumors, 61.2% had advanced nodal involvement (cN2 or cN3), and 15.1% presented distant metastases. Pathologically, 72.2% had pT3 tumors, while 43% were pN0 after lymphadenectomy. Surgical treatment was performed in 95.2% of patients, mainly partial or radical penectomy. Postoperative complications occurred in 19.5%, primarily Clavien-Dindo grade II. Adjuvant radiotherapy and chemotherapy were administered to 11.6% and 13.5% of patients, respectively. Disease-related mortality was 10.1%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>A high proportion of patients presented with locally advanced or metastatic disease, reflecting delayed diagnosis and access barriers. These findings highlight the need for public health interventions focused on early detection, sexual health education, and improved referral systems to reduce the burden of penile cancer in Colombia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03915603261481569","type":"journal-article","created":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T23:54:20Z","timestamp":1787961260000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical and epidemiological characteristics of penile cancer in a hospital-based cohort from southwestern Colombia"],"prefix":"10.1177","author":[{"given":"Nicol\u00e1s","family":"Guerr\u00f3n Morales","sequence":"first","affiliation":[{"name":"UROGIV Research Group, School of Medicine, Universidad del Valle, Cali, Colombia"},{"name":"Division of Urology\/Urooncology, Department of Surgery, School of Medicine, Universidad del Valle, Cali, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe E.","family":"Spiess","sequence":"additional","affiliation":[{"name":"Department of Genitourinary Oncology and Tumor Biology, H. Lee Moffitt Cancer Center &amp; Research Institute, Tampa, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6945-8261","authenticated-orcid":false,"given":"Herney Andr\u00e9s","family":"Garc\u00eda-Perdomo","sequence":"additional","affiliation":[{"name":"UROGIV Research Group, School of Medicine, Universidad del Valle, Cali, Colombia"},{"name":"Division of Urology\/Urooncology, Department of Surgery, School of Medicine, Universidad del Valle, Cali, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,8,28]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","unstructured":"Genes WP Fierro MC Guerrero AE et al. Guia de c\u00e1ncer de pene de la Sociedad Colombiana de Urolog\u00eda. Urol Colomb 2022; 31(01): e32\u2013e40. https:\/\/doi.org\/10.1055\/s-0041-1740533","DOI":"10.1055\/s-0041-1740533"},{"key":"e_1_3_2_3_2","volume-title":"Cancer site ranking","author":"GLOBOCAN","year":"2022","unstructured":"GLOBOCAN. Cancer site ranking. GLOBOCAN, 2022."},{"key":"e_1_3_2_4_2","unstructured":"Chipollini J De la Rosa AH Azizi M et al. Patient presentation differential diagnosis and management of penile lesions. Can Urol Assoc J 2019; 13(2 Suppl 1): S2\u2013S8. https:\/\/doi.org\/10.5489\/cuaj.5712"},{"key":"e_1_3_2_5_2","doi-asserted-by":"crossref","unstructured":"Vieira CB Feitoza L Pinho J et al. Profile of patients with penile cancer in the region with the highest worldwide incidence. Sci Rep 2020; 10(1): 2965. https:\/\/doi.org\/10.1038\/s41598-020-59831-5","DOI":"10.1038\/s41598-020-59831-5"},{"key":"e_1_3_2_6_2","doi-asserted-by":"crossref","unstructured":"Brouwer OR Rumble RB Ayres B et al. Penile cancer: EAU-ASCO collaborative guidelines update q and A. JCO Oncol Pract 2024; 20(1): 33\u201337. https:\/\/doi.org\/10.1200\/op.23.00585","DOI":"10.1200\/OP.23.00585"},{"key":"e_1_3_2_7_2","doi-asserted-by":"crossref","unstructured":"Sanchez DF Soares F Alvarado-Cabrero I et al. Pathological factors behavior and histological prognostic risk groups in subtypes of penile squamous cell carcinomas (SCC). Semin Diagn Pathol 2015; 32(3): 222\u2013231. https:\/\/doi.org\/10.1053\/j.semdp.2014.12.017","DOI":"10.1053\/j.semdp.2014.12.017"},{"key":"e_1_3_2_8_2","doi-asserted-by":"crossref","unstructured":"Rengifo LM Herrera MDM Rincon-Jimenez AL et al. Penile cancer in Cali Colombia: 10 years of casuistry in a tertiary referral center of a middle-income country. Int J Med Stud 2014; 2(3): 109\u2013114. https:\/\/doi.org\/10.5195\/ijms.2014.98","DOI":"10.5195\/ijms.2014.98"},{"key":"e_1_3_2_9_2","unstructured":"Engelsgjerd JS Leslie SW LaGrange CA. Penile cancer and penile intraepithelial neoplasia. 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