{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:11:47Z","timestamp":1790691107456,"version":"4.1.0"},"reference-count":15,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T00:00:00Z","timestamp":1790467200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Urologia"],"abstract":"<jats:p>\n                    Urethral stricture recurrence after optical internal urethrotomy (OIU) is well documented, with published rates of 40%\u201368% at 1\u2009year. This prospective randomised controlled trial assigned 50 male patients with primary short-segment (&lt; 2\u2009cm) inflammatory bulbar urethral strictures to OIU augmented by intralesional triamcinolone acetonide 40\u2009mg (Group A,\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u200925) or OIU alone (Group B,\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u200925) at a tertiary urology unit in Chennai, India (January\u2013December 2024). Primary outcome was maximum urinary flow rate (Qmax) at 1\u2009month post-catheter removal; secondary outcome was cumulative stricture recurrence at 8\u2009months. Baseline characteristics were comparable between groups. At 1\u2009month, mean Qmax was 15.76\u2009\u00b1\u20091.98\u2009ml\/s in Group A versus 14.24\u2009\u00b1\u20091.98\u2009ml\/s in Group B (mean difference\u2009+\u20091.52\u2009ml\/s, 95% CI 0.39\u20132.65;\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009=\u20090.0092; Cohen\u2019s\n                    <jats:italic toggle=\"yes\">d<\/jats:italic>\n                    \u2009=\u20090.767). Cumulative 8-month recurrence was 12% (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u20093) in Group A and 40% (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u200910) in Group B (relative risk 0.30, 95% CI 0.09\u20130.96; absolute risk reduction 28%; number needed to treat 3.6; Fisher exact\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009=\u20090.051). No serious adverse events were attributable to triamcinolone. Intralesional triamcinolone acetonide at the time of OIU improves early urinary flow and reduces short-term recurrence with a favourable safety profile.\n                  <\/jats:p>","DOI":"10.1177\/03915603261486072","type":"journal-article","created":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T17:48:21Z","timestamp":1790531301000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Optical internal urethrotomy alone versus optical internal urethrotomy with intralesional triamcinolone acetonide for short-segment anterior urethral stricture: A prospective randomised controlled trial"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-7819-3416","authenticated-orcid":false,"given":"Venkata Ramana","family":"Korrapati","sequence":"first","affiliation":[{"name":"Department of Urology, Sri Ramachandra Medical College and Research Institute, SRIHER, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lakshmi Kandhan","family":"L","sequence":"additional","affiliation":[{"name":"Department of Urology, Sri Ramachandra Medical College and Research Institute, SRIHER, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venkateshen","family":"Palanisamy","sequence":"additional","affiliation":[{"name":"Department of Urology, Sri Ramachandra Medical College and Research Institute, SRIHER, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natarajan","family":"Kumaresan","sequence":"additional","affiliation":[{"name":"Department of Urology, Sri Ramachandra Medical College and Research Institute, SRIHER, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Chandru","sequence":"additional","affiliation":[{"name":"Department of Urology, Sri Ramachandra Medical College and Research Institute, SRIHER, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rubina","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Urology, Sri Ramachandra Medical College and Research Institute, SRIHER, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,27]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"crossref","unstructured":"Mundy AR Andrich DE. Urethral strictures. BJU Int 2011; 107(1): 6\u201326. https:\/\/doi.org\/10.1111\/j.1464-410X.2010.09800.x","DOI":"10.1111\/j.1464-410X.2010.09800.x"},{"key":"e_1_3_3_3_2","doi-asserted-by":"crossref","unstructured":"Bullock TL Brandes SB. Adult anterior urethral strictures: a national practice patterns survey of board certified urologists in the United States. J Urol 2007; 177(2): 685\u2013690. https:\/\/doi.org\/10.1016\/j.juro.2006.09.052","DOI":"10.1016\/j.juro.2006.09.052"},{"key":"e_1_3_3_4_2","doi-asserted-by":"crossref","unstructured":"Santucci RA Joyce GF Wise M. Male urethral stricture disease. J Urol 2007; 177(5): 1667\u20131674. https:\/\/doi.org\/10.1016\/j.juro.2007.01.041","DOI":"10.1016\/j.juro.2007.01.041"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)65942-1"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)65296-0"},{"key":"e_1_3_3_7_2","article-title":"Improving predictive utility of urethral stricture classification systems based on survival analysis of stricture-specific variables (LERNS)","volume":"210","author":"Rourke K.","year":"2023","unstructured":"Rourke K. Improving predictive utility of urethral stricture classification systems based on survival analysis of stricture-specific variables (LERNS). J Urol 2023; 210(Suppl): Abstract MP78-10.","journal-title":"J Urol"},{"key":"e_1_3_3_8_2","first-page":"1055","volume-title":"Campbell-Walsh Urology","author":"Jordan GH","year":"2007","unstructured":"Jordan GH, Schlossberg SM. Surgery of the penis and urethra. In: Wein AJ, Kavoussi LR, Novick AC (eds) Campbell-Walsh Urology. 9th ed. Saunders, 2007, pp.1055\u20131075.","edition":"9"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000154347.24230.f1"},{"key":"e_1_3_3_10_2","doi-asserted-by":"crossref","unstructured":"Kumar S Garg N Singh SK et al. Efficacy of optical internal urethrotomy and intralesional injection of Vatsala-Santosh PGI Tri-Inject (Triamcinolone Mitomycin C and Hyaluronidase) in the treatment of Anterior Urethral Stricture. Adv Urol 2014; 2014: 192710. https:\/\/doi.org\/10.1155\/2014\/192710","DOI":"10.1155\/2014\/192710"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1159\/000473209"},{"key":"e_1_3_3_12_2","doi-asserted-by":"crossref","unstructured":"Mazdak H Izadpanahi MH Ghalamkari A et al. Internal urethrotomy and intraurethral submucosal injection of triamcinolone in short bulbar urethral strictures. Int Urol Nephrol 2010; 42(3): 565\u2013568. https:\/\/doi.org\/10.1007\/s11255-009-9663-5","DOI":"10.1007\/s11255-009-9663-5"},{"issue":"2","key":"e_1_3_3_13_2","first-page":"132","article-title":"Triamcinolone injection following internal urethrotomy for treatment of urethral stricture","volume":"8","author":"Tabassi KT","year":"2011","unstructured":"Tabassi KT, Yarmohamadi A, Mohammadi S. Triamcinolone injection following internal urethrotomy for treatment of urethral stricture. Urol J 2011; 8(2): 132\u2013136.","journal-title":"Urol J"},{"key":"e_1_3_3_14_2","doi-asserted-by":"crossref","unstructured":"Beheruk K Maiti K Sarkar D. Role of intralesional steroid and hyaluronidase injection in reducing recurrence of urethral stricture after direct visual internal urethrotomy: a prospective study. Urologia 2025; 93. https:\/\/doi.org\/10.1177\/03915603251387896","DOI":"10.1177\/03915603251387896"},{"key":"e_1_3_3_15_2","doi-asserted-by":"crossref","unstructured":"Ghose A Haque MMU Mazumder MKU et al. Outcome of triamcinolone injection following optical internal urethrotomy in short segment anterior urethral stricture. IAHS Med J 2024; 6(1): 20\u201324. https:\/\/doi.org\/10.3329\/iahsmj.v6i1.75545","DOI":"10.3329\/iahsmj.v6i1.75545"},{"issue":"10","key":"e_1_3_3_16_2","first-page":"685","article-title":"Assessment of predictive factors in endoscopic internal urethrotomy for bulbar urethral strictures","volume":"48","author":"Bizzarri FP","year":"2024","unstructured":"Bizzarri FP, Campetella M, Ragonese M, et al. Assessment of predictive factors in endoscopic internal urethrotomy for bulbar urethral strictures. Actas Urol Esp 2024; 48(10): 685\u2013687.","journal-title":"Actas Urol Esp"}],"container-title":["Urologia Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03915603261486072","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03915603261486072","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03915603261486072","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T13:49:35Z","timestamp":1790689775000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03915603261486072"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,27]]},"references-count":15,"alternative-id":["10.1177\/03915603261486072"],"URL":"https:\/\/doi.org\/10.1177\/03915603261486072","relation":{},"ISSN":["0391-5603","1724-6075"],"issn-type":[{"value":"0391-5603","type":"print"},{"value":"1724-6075","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,27]]},"article-number":"03915603261486072"}}