{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T08:56:45Z","timestamp":1777712205346,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2016,7,7]],"date-time":"2016-07-07T00:00:00Z","timestamp":1467849600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Immunopathol Pharmacol"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:p>We reported a case of an 11-year-old girl admitted to our hospital for goiter, tachycardia, sweating, and visible and palpable thyroid. Thyroid function tests revealed a low thyrotropin level (&lt;0.004 mIU\/L) and elevated free thyroxine level (3.4 ng\/ dL) diagnosed with Graves\u2019 disease and treated with methimazole. This anti-thyroid drug is recommended as first-line treatment in children with Graves\u2019 disease because it produces minor adverse effects with respect to propylthiouracil. She developed a lateralized exanthem mimicking figurate inflammatory dermatosis of infancy after methimazole therapy. The symptoms resolved after discontinuation of methimazole and treatment with an antihistamine and a corticosteroid. Furthermore, the treatment was changed to propylthiouracil without any adverse effects. According to current literature this is the first case of cutaneous figurate erythema related to methimazole, different from other well-known reactions such as skin eruption or urticaria.<\/jats:p>","DOI":"10.1177\/0394632016652412","type":"journal-article","created":{"date-parts":[[2016,6,7]],"date-time":"2016-06-07T22:53:17Z","timestamp":1465339997000},"page":"707-711","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Lateralized exanthem mimicking figurate inflammatory dermatosis of infancy after methimazole therapy"],"prefix":"10.1177","volume":"29","author":[{"given":"T","family":"Arrigo","sequence":"first","affiliation":[{"name":"Department of Human Pathology of Adult and Developmental Evolutive Age, University of Messina, Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PM","family":"Cutroneo","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Vaccaro","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Impollonia","sequence":"additional","affiliation":[{"name":"Department of Human Pathology of Adult and Developmental Evolutive Age, University of Messina, Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"Squadrito","sequence":"additional","affiliation":[{"name":"Department of Human Pathology of Adult and Developmental Evolutive Age, University of Messina, Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Mecchio","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Salpietro","sequence":"additional","affiliation":[{"name":"Department of Human Pathology of Adult and Developmental Evolutive Age, University of Messina, Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Altavilla","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,7,7]]},"reference":[{"key":"bibr1-0394632016652412","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra042972"},{"key":"bibr2-0394632016652412","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-2752"},{"key":"bibr3-0394632016652412","doi-asserted-by":"publisher","DOI":"10.1159\/000223414"},{"key":"bibr4-0394632016652412","doi-asserted-by":"publisher","DOI":"10.1515\/jpem.2011.194"},{"key":"bibr5-0394632016652412","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-2135"},{"key":"bibr6-0394632016652412","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2008.00646.x"},{"key":"bibr7-0394632016652412","doi-asserted-by":"publisher","DOI":"10.1006\/jaut.2000.0499"},{"key":"bibr8-0394632016652412","doi-asserted-by":"publisher","DOI":"10.1080\/00015550310016562"},{"key":"bibr9-0394632016652412","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2004.14.964"},{"key":"bibr10-0394632016652412","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2004.05.045"},{"issue":"3","key":"bibr11-0394632016652412","first-page":"185","volume":"21","author":"Vaccaro M","year":"2013","journal-title":"Acta Dermatovenerologica Croatia"},{"key":"bibr12-0394632016652412","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.06.039"},{"key":"bibr13-0394632016652412","doi-asserted-by":"publisher","DOI":"10.1111\/ced.12311"},{"key":"bibr14-0394632016652412","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1981.154"},{"key":"bibr15-0394632016652412","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2006.00901.x"},{"key":"bibr16-0394632016652412","first-page":"121","volume":"136","author":"Wing SS","year":"1987","journal-title":"CMAJ: Canadian Medical Association Journal"},{"key":"bibr17-0394632016652412","doi-asserted-by":"publisher","DOI":"10.2337\/dc05-2087"},{"key":"bibr18-0394632016652412","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2005.15.1333"},{"key":"bibr19-0394632016652412","doi-asserted-by":"publisher","DOI":"10.1186\/1687-9856-2010-176970"},{"key":"bibr20-0394632016652412","doi-asserted-by":"publisher","DOI":"10.1159\/000320028"},{"key":"bibr21-0394632016652412","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2012.04365.x"},{"key":"bibr22-0394632016652412","first-page":"474","volume":"42","author":"Ostlere S","year":"1988","journal-title":"British Journal of Clinical Practice"},{"key":"bibr23-0394632016652412","doi-asserted-by":"publisher","DOI":"10.4158\/EP09304.CR"}],"container-title":["International Journal of Immunopathology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0394632016652412","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0394632016652412","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0394632016652412","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:04:34Z","timestamp":1777457074000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0394632016652412"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,7]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["10.1177\/0394632016652412"],"URL":"https:\/\/doi.org\/10.1177\/0394632016652412","relation":{},"ISSN":["0394-6320","2058-7384"],"issn-type":[{"value":"0394-6320","type":"print"},{"value":"2058-7384","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,7]]}}}