{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:57:47Z","timestamp":1787169467962,"version":"build-2736575974"},"reference-count":4,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2016,9,21]],"date-time":"2016-09-21T00:00:00Z","timestamp":1474416000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Immunopathol Pharmacol"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:p>Treatment-related myelodysplastic syndrome (t-MDS)\/acute myeloid leukemia (AML) is a devastating early or late complication of treatment for childhood cancer related with a significant morbidity and mortality. We retrospectively studied survivors of childhood cancer. Overall, 287 patients were recorded in the databases and we identified three (1.04%) with t-MDS. The primary cancer diagnoses were Langerhans cell histiocytosis (one patient) and acute lymphoblastic leukemia (ALL; two patients). The mean age of patients was 12.1 years. All patients had received systemic antifungal treatment for invasive pulmonary aspergillosis successfully treated with voriconazole and liposomal amphotericin B before diagnosis of t-MDS. Two patients (66%) remain alive after a median follow-up period of 3.5 years.<\/jats:p>","DOI":"10.1177\/0394632016670667","type":"journal-article","created":{"date-parts":[[2016,9,19]],"date-time":"2016-09-19T20:57:56Z","timestamp":1474318676000},"page":"729-730","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Treatment-related myelodysplastic syndrome (t-MDS)\/acute myeloid leukemia (AML) in children with cancer: A single-center experience"],"prefix":"10.1177","volume":"29","author":[{"given":"Athanasios","family":"Tragiannidis","sequence":"first","affiliation":[{"name":"2nd Pediatric Department, Aristotle University of Thessaloniki, AHEPA Hospital, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaos","family":"Gombakis","sequence":"additional","affiliation":[{"name":"2nd Pediatric Department, Aristotle University of Thessaloniki, AHEPA Hospital, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Papageorgiou","sequence":"additional","affiliation":[{"name":"2nd Pediatric Department, Aristotle University of Thessaloniki, AHEPA Hospital, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Hatzipantelis","sequence":"additional","affiliation":[{"name":"2nd Pediatric Department, Aristotle University of Thessaloniki, AHEPA Hospital, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodotis","family":"Papageorgiou","sequence":"additional","affiliation":[{"name":"2nd Pediatric Department, Aristotle University of Thessaloniki, AHEPA Hospital, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Hatzistilianou","sequence":"additional","affiliation":[{"name":"2nd Pediatric Department, Aristotle University of Thessaloniki, AHEPA Hospital, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,9,21]]},"reference":[{"key":"bibr1-0394632016670667","doi-asserted-by":"publisher","DOI":"10.1080\/10428190500051042"},{"key":"bibr2-0394632016670667","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-03-643544"},{"key":"bibr3-0394632016670667","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0b013e3181ba43dc"},{"key":"bibr4-0394632016670667","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V78.11.2982.2982"}],"container-title":["International Journal of Immunopathology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0394632016670667","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0394632016670667","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0394632016670667","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:04:36Z","timestamp":1777457076000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0394632016670667"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,21]]},"references-count":4,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["10.1177\/0394632016670667"],"URL":"https:\/\/doi.org\/10.1177\/0394632016670667","relation":{},"ISSN":["0394-6320","2058-7384"],"issn-type":[{"value":"0394-6320","type":"print"},{"value":"2058-7384","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,21]]}}}