{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T15:39:02Z","timestamp":1784561942910,"version":"3.55.0"},"reference-count":18,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2017,8,8]],"date-time":"2017-08-08T00:00:00Z","timestamp":1502150400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Immunopathol Pharmacol"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:p>Cloxacillin, a semisynthetic penicillin is a potent inhibitor of most penicillinase-producing Staphylococci. Use of high doses of Cloxacillin for 6\u2009weeks is recommended for the treatment of infective endocarditis caused by methicillin-susceptible Staphylococcus aureus (MSSA). Here, we report a case of Cloxacillin-induced agranulocytosis in a patient treated for MSSA native tricuspid valve endocarditis, which was resolved after discontinuation of the antibiotic. This case report highlights a rare adverse event of a commonly used antibiotic.<\/jats:p>","DOI":"10.1177\/0394632017724320","type":"journal-article","created":{"date-parts":[[2017,8,8]],"date-time":"2017-08-08T10:59:32Z","timestamp":1502189972000},"page":"297-301","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Cloxacillin induced agranulocytosis: A rare adverse event of a commonly used antibiotic"],"prefix":"10.1177","volume":"30","author":[{"given":"Selvin Sundar Raj","family":"Mani","sequence":"first","affiliation":[{"name":"Department of Medicine, Christian Medical College, Vellore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramya","family":"Iyyadurai","sequence":"additional","affiliation":[{"name":"Department of Medicine, Christian Medical College, Vellore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,8,8]]},"reference":[{"key":"bibr1-0394632017724320","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(10)70285-1"},{"key":"bibr2-0394632017724320","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1981.154"},{"key":"bibr3-0394632017724320","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1979.03300070019017"},{"key":"bibr4-0394632017724320","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.8.869"},{"key":"bibr5-0394632017724320","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.159.6.607"},{"key":"bibr6-0394632017724320","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2014-208324."},{"key":"bibr7-0394632017724320","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.2830120213"},{"key":"bibr8-0394632017724320","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.31.11.1657"},{"key":"bibr9-0394632017724320","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/152.1.90"},{"key":"bibr10-0394632017724320","doi-asserted-by":"publisher","DOI":"10.1007\/BF00117853"},{"issue":"46","key":"bibr11-0394632017724320","first-page":"1821","volume":"108","author":"Krafft T","year":"1978","journal-title":"Schweizerische Medizinische Wochenschrift"},{"key":"bibr12-0394632017724320","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.1966.tb03126.x"},{"key":"bibr13-0394632017724320","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197402212900803"},{"key":"bibr14-0394632017724320","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1400762"},{"key":"bibr15-0394632017724320","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-06-723742"},{"key":"bibr16-0394632017724320","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-12-754481"},{"key":"bibr17-0394632017724320","doi-asserted-by":"publisher","DOI":"10.1038\/gim.2016.33"},{"key":"bibr18-0394632017724320","doi-asserted-by":"publisher","DOI":"10.1097\/FPC.0000000000000172"}],"container-title":["International Journal of Immunopathology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0394632017724320","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0394632017724320","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0394632017724320","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:04:48Z","timestamp":1777457088000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0394632017724320"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,8]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["10.1177\/0394632017724320"],"URL":"https:\/\/doi.org\/10.1177\/0394632017724320","relation":{},"ISSN":["0394-6320","2058-7384"],"issn-type":[{"value":"0394-6320","type":"print"},{"value":"2058-7384","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,8]]}}}