{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T08:38:49Z","timestamp":1777711129232,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Immunopathol Pharmacol"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:p>Introduction: During COVID-19 pandemic, the massive use of Personal Protective Equipment could provoke severe adverse reactions in latex allergy patients and could negatively affect their quality of life. Methods: Trough a survey the study aimed: (a) to evaluate the incidence of allergic reactions in patients with latex allergy during the SARS-CoV-2 pandemic; (b) to evaluate the protective role of continuous latex sublingual immunotherapy (SLIT) during this period; and (c) to evaluate quality of life of natural rubber latex allergy (NRLA) patients during the pandemic. Results: 67 patients (9 males and 58 females, mean age of 45.9 \u00b1 11.4\u00a0years) suffering from latex allergy were included in the present study. We recorded among our patients 13 cases (34.2%) of urticarial\/angioedema (U\/A), 9 cases (23.6%) of respiratory symptoms (dyspnoea, shortness of breath and wheezing) and 7 cases (18.4%) of anaphylaxis. In patients who underwent continuous SLIT, we observed less cases of U\/A ( p &lt; 0.001), respiratory symptoms ( p &lt; 0.001), anaphylaxis ( p = 0.003), hospitalizations ( p = 0.014) and a lower therapy administration. We compared the results of SF-36 questionnaire in patients who underwent continuous and not-continuous SLIT with a significance differences score between these two groups. Conclusions: Our study is the first that investigated the clinical and quality of life effects of COVID-19 pandemic in NRLA patients.<\/jats:p>","DOI":"10.1177\/03946320221100367","type":"journal-article","created":{"date-parts":[[2022,5,18]],"date-time":"2022-05-18T18:58:29Z","timestamp":1652900309000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinical and quality of life assessment in patients with latex allergy during COVID-19 pandemic: Possible protective role of continuous latex immunotherapy"],"prefix":"10.1177","volume":"36","author":[{"given":"Alessia","family":"Di Rienzo","sequence":"first","affiliation":[{"name":"Allergy Unit of Fondazione Policlinico Universitario A.Gemelli IRCCS, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Urbani","sequence":"additional","affiliation":[{"name":"Allergy Unit of Fondazione Policlinico Universitario A.Gemelli IRCCS, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Longhino","sequence":"additional","affiliation":[{"name":"Allergy Unit of Fondazione Policlinico Universitario A.Gemelli IRCCS, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caterina","family":"Sarnari","sequence":"additional","affiliation":[{"name":"Allergy Unit of Fondazione Policlinico Universitario A.Gemelli IRCCS, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Buonomo","sequence":"additional","affiliation":[{"name":"Allergy Unit of Fondazione Policlinico Universitario A.Gemelli IRCCS, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Rizzi","sequence":"additional","affiliation":[{"name":"Allergy Unit of Fondazione Policlinico Universitario A.Gemelli IRCCS, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6746-9044","authenticated-orcid":false,"given":"Arianna","family":"Aruanno","sequence":"additional","affiliation":[{"name":"Allergy Unit of Fondazione Policlinico Universitario A.Gemelli IRCCS, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleonora","family":"Nucera","sequence":"additional","affiliation":[{"name":"Allergy Unit of Fondazione Policlinico Universitario A.Gemelli IRCCS, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,5,15]]},"reference":[{"key":"bibr1-03946320221100367","doi-asserted-by":"publisher","DOI":"10.1038\/s41423-020-0372-4"},{"key":"bibr2-03946320221100367","doi-asserted-by":"publisher","DOI":"10.1539\/joh.15-0275-RA"},{"key":"bibr3-03946320221100367","doi-asserted-by":"publisher","DOI":"10.29262\/ram.v64i4.289"},{"issue":"1","key":"bibr4-03946320221100367","first-page":"30","volume":"114","author":"Parisi CAS","year":"2016","journal-title":"Archivos Argentinos de Pediatria"},{"issue":"5","key":"bibr5-03946320221100367","first-page":"1212","volume":"5","author":"Kelly KJ","year":"2017","journal-title":"Journal of Allergy and Clinical 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